Goal: Empower students to win awards, create Innovative products and start companies
        Prof. Phani Kumar Pullela

        PhD, Postdoc, MBA (Pharma)

        E-mail ID: phanikumar.p@cmrit.ac.in
        Mobile No: +91-9902005868/9480573868
      
   
Experience

Seven years of experience in Biomedical diagnostics  company as Head-Chemistry
Four and half years experience as postdoctoral fellow at Marquette University, USA
Five international awards, More than 10 research grants, more than 12 awards for PKP's students
10 International Patents, 15 research publications, Four products in the market
Experience & enthusiasm in working in any branch of Science or Engineering.
4 years as professor in CMRIT, Innovation and Entrepreneurship faculty.

Areas of Interest in Teaching

Engineering Chemistry

Supplementary: Any area of Chemistry, Grant writing, Idea generation, Product development, Patent Drafting and Entrepreneurship.



Areas of Interest in Research

Chemical Biology, Fluorescence, Biomedical devices, Fluorescent sensors, Societal research( Water exploratory projects)  and Product development in any field/branch of Science and engineering.


Mentor ship

current PhD students under his guidance: 5



Grants

  • Department of Defense, USA, Breast Cancer Concept Award (2005-2006) - First postdoctoral fellow in USA to receive the BCRP concept award
  • Department of Biotechnology (SBIRI scheme, 2007-2008)
  • Defense Research Development Establishment (DRDE, 2008-2009)
  • DRDE (2010-2014)-Development of fluorescent gas sensor for nerve agents
  • Part of the team which obtained international grants; Grand challenges Canada Phase II,FIND Grant.
  • Part of the team which also obtained Indian grants ICMR, BIPP (DBT), NPMASS: , NMITLI Phase II.
  • VGST SMYSR 2015
  • DST Nanomission 2016
  • IsquareD Water exploratory research fellow, 2016
  • AICTE SPDP 2017
  • DST Texas Instruments 2017
  • Karnataka Govt Grand challenge( 2 grants), 2018
  • Govt Of India BIRAC SOCH 2018
  • DBT Foldoscope 2018
Research Publications

Effect of Hofmeister series salts on Absorptivity of aqueous solutions on Sodium polyacrylate
IOP Conference Series: Materials Science and Engineering 263 (2), 022028 (2017)

Efficient bulk scale synthesis of popular pesticide synthon: tetrachlorothiophene
Catalysis, Structure & Reactivity 3 (3), 138-145 (2017)

Objective measurement of isoniazid levels: practical approach for monitoring tuberculosis drug treatment adherence
S Korrapati, C Muneppa, PK Pullela, GK Shivashankar, U Vijayalakshmi
IET Nanobiotechnology 11 (7), 821-826 2017

M Chandrappa, GVS Reddy, R Fazlur, BN Murthy, PK Pullela, SG Kumar
 Chemical Papers, 1-9 2017

Bulk Synthesis of Thermally Unstable 5-Amino-3-methylisoxazole Using Silica Coated Magnetite Nanoparticles (Fe^ sub 3^ O^ sub 4$@ SiO^ sub 2^)

GVS Reddy, M Chandrappa, F Rahaman, BN Murthy, PK Pullela
Asian Journal of Chemistry 29 (1), 124 2017

SPA enhanced FPIA-based detection of pesticide residue with ppb/ppt level detection limit
S Korrapati, PK Pullela, U Vijayalakshmi
IET nanobiotechnology 11 (1), 24-31 2016

Differential diagnosis of malaria on truelab Uno®, a portable, real-time, MicroPCR device for point-of-care applications
CB Nair, J Manjula, PA Subramani, PB Nagendrappa, MN Manoj, ...
PloS one 11 (1), e0146961 2016

Effect of Hofmeister series salts and BSA on fluorescein compounds
S Korrapati, SK Sanjeeva, U Vijayalakshmi, PK Pullela
International Journal of Chemical Technology Research 8 (12), 348-359 2015

SK Sanjeeva, MP Pinto, MM Narayanan, GM Kini, CB Nair, PV SubbaRao, ...
Renewable energy 71, 81-88 2014

SK Sanjeeva, S Korrapati, CB Nair, PVS Rao, PK Pullela, U Vijayalakshmi, ...
Journal of fluorescence 24 (4), 1297-1306 2014
C McCullough, PK Pullela, SC Im, L Waskell, D Sem
Cytochrome P450 Protocols, 51-59 2013
MM Narayanan, CB Nair, SK Sanjeeva, PVS Rao, PK Pullela, CJ Barrow
Advances and applications in bioinformatics and chemistry: AABC 6, 47 2013
CR McCullough, PK Pullela, SC Im, L Waskell, DS Sem
Journal of biomolecular NMR 43 (3), 171-178 2009
H Yao, CR McCullough, AD Costache, PK Pullela, DS Sem
Proteins: Structure, Function, and Bioinformatics 69 (1), 125-138 2007
T Chiku, PK Pullela, DS Sem
Journal of biomolecular screening 11 (7), 844-853 2006
PK Pullela
MARQUETTE UNIV MILWAUKEE WI 2006
PK Pullela, T Chiku, MJ Carvan III, DS Sem
Analytical biochemistry 352 (2), 265-273 2006
AD Costache, PK Pullela, P Kasha, H Tomasiewicz, DS Sem
Molecular Endocrinology 19 (12), 2979-2990 2005
R Paramashivappa, PP Kumar, PVS Rao, AS Rao
Bioorganic & medicinal chemistry letters 13 (4), 657-660 2003
R Paramashivappa, PP Kumar, PVS Rao, AS Rao
Tetrahedron letters 44 (5), 1003-1005 2003
R Paramashivappa, P Phani Kumar, PV Subba Rao, A Srinivasa Rao
Journal of agricultural and food chemistry 50 (26), 7709-7713 2002
P Phani Kumar, R Paramashivappa, PJ Vithayathil, PV Subba Rao, ...
Journal of Agricultural and Food Chemistry 50 (16), 4705-4708 2002
PP Kumar, SC Stotz, R Paramashivappa, AM Beedle, GW Zamponi, ...
Molecular pharmacology 61 (3), 649-658 2002
R Paramashivappa, PP Kumar, PJ Vithayathil, AS Rao
Journal of Agricultural and Food Chemistry 49 (5), 2548-2551 2001
A novel method for isolation of all major phenolic constituents from cashew (Anacardium occidentale) nut shell liquid  
J. Agric. Food Chem. 49, 2548- 2551, 2001.
Authors: R. Paramshivappa, Phani Kumar Pullela, P.J.Vithayathil, A.Srinivasa Rao
Current citations: 95, Journal Impact Factor: 2.823


Process for isolation of cardanol from technical cashew (Anacardium occidentale) nut shell liquid
J. Agric. Food Chem. 50, 4705-4708, 2002.
Authors: Phani Kumar Pullela, R. Paramshivappa, P.J.Vithayathil, P. V. Subba Rao, A.Srinivasa Rao
Current citations: 84, Journal Impact Factor: 2.823


Synthesis of sildenafil analogues from anacardic acid and their phosphodiesterase-5 (PDE5) Inhibition
J. Agric. Food Chem. 50, 7709-7713, 2002.
Authors: R. Paramashivappa, Phani Kumar Pullela, P. V. Subba Rao, A. Srinivasa Rao.
Current citations: 20, Journal Impact Factor: 2.823
 
Synthesis and evaluation of a new class of nifedipine analogs with T-type calcium channel activity 
Molecular Pharmacology 61, 649-658, 2002.
Authors: Phani Kumar Pullela, Stephanie C Stotz, R. Paramashivappa, Aaron M Beedle, Gerald W. Zamponi, A. Srinivasa Rao
Current citations: 55, Journal Impact Factor: 6.58

Design, synthesis and biological evaluation of benzimidazole / benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors
Biorg. Med. Chem. Lett. 13, 657-660, 2003.
Authors: R. Paramashivappa, Phani Kumar Pullela, P. V. Subba Rao, A. Srinivasa Rao.
Current citations: 126, Journal Impact Factor: 2.66

Simple and efficient method for the synthesis of 2', 3'-didehydro-3'-deoxy- thymidine (d4T) 
Tetrahedron Lett. 44, 1003-1005, 2003.
Authors: R. Paramashivappa, Phani Kumar Pullela, P. V. Subba Rao, A. Srinivasa Rao.
Current citations: 14, Journal Impact Factor: 2.683

Homology modeled ligand-binding domains of zebrafish estrogen receptors #, #1, and #2: from insilico to invivo studies of estrogen interactions in Danio rerio as a model system
Mol. Endocrinol. 19, 2979- 2990, 2005.
Authors: Aurora D. Costache, Phani Kumar Pullela, Purnachandar Kasha, Daniel S. Sem.
Current citations: 17, Journal Impact Factor: 4.54

Fluorescence based detection of thiols in vitro and in vivo with DSSA probe
Anal. Biochem 352, 265-273, 2006.
Authors: Phani Kumar Pullela, Taurai Chiku, Michael J. Caravan III, Daniel S. Sem
Current citations: 65, Journal Impact Factor: 2.996

A dithio coupled kinase and ATPase assay  
J. Biomol. Screen. 11, 844-853, 2006. 
Authors: Taurai Chiku, Phani Kumar Pullela, Daniel S. Sem
Current citations: 6, Journal Impact Factor: 2.5


Structural Evidence for a Functionally Relevant Second Camphor Binding Site in P450cam: Model for Substrate Entry into a P450 Active Site
Proteins: Structure, Function, and Bioinformatics 69, 125- 138, 2007.
Authors: Huili Yao, Christopher R. McCullough, Aurora D. Costache, Phani Kumar Pullela, Daniel S. Sem.
Current citations: 20, Journal Impact Factor: 3.392

13C-Methyl isocyanide as an NMR probe for cytochrome P450 active site
Journal of Biomolecular NMR 43, 171-178, 2009.
Authors: Christopher R. McCullough, Sang-Choul Im, Lucy Waskell, Phani Kumar Pullela, and Daniel S. Sem.
Currently cited: 3, Journal Impact Factor: 3.047

Design of multiligand inhibitors for the swine flu H1N1 neuraminidase binding site
Advances and Applications in Bioinformatics and Chemistry 6, 47-53, 2013
Authors: Manoj M Narayanan, Chandrasekhar B Nair, Shilpa K Sanjeeva, PV Subba Rao, Phani K Pullela, Colin J Barrow.


Reviews


Books

NMR driven Chemical Proteomics

CRC press 2006, Authors: Phani Kumar Pullela and Daniel Sem

Book article in "Separation methods in proteomics", Current citations: 9


The Synthesis, Characterization, and Application of 13C-Methyl Isocyanide as an NMR Probe of Heme Protein Active Sites


Springer Protocols, 2013, Christopher McCullough, Phani Kumar Pullela, Sang-ChoulIm, Lucy Waskell, Daniel Sem. Book Article in “Cytochrome P450 Protocols”





PK Pullela, P Rangappa, SR Alapati, PV Subbarao, JA Bibbs

US Patent 6,852,742 2005

DS Sem, PK Pullela
US Patent 7,820,833 2010

PK Pullela, P Rangappa, SR Alapati, PV Subbarao

US Patent 7,687,511 2010

CB Nair, PV Subbarao, P Pullela, GM Kini
US Patent 8,282,692 2012

A Kumar, J Sinha, PK Pullela

US Patent App. 13/126,204 2011

PK Pullela, MN Manoj, SK Gandhavalla, MP Pinto, CB Nair, PV Subbarao

US Patent 8,986,976 2015

CB Nair, PV Subbarao, PK Pullela, GM Kini
US Patent 9,228,144 2016

1,4- dihydropyridine and pyridine compounds as calcium channel blocker
United States Patent 6,852,742
Inventors: Phani Kumar Pullela, R. Paramashivappa, A Srinivasa Rao, P.V. Subbarao, Jeffrey A. Bibbs
This project was coined to develop a dihydropyridine based T-type calcium channel blocker and the product PPK-5 was licensed
 to Diakron Pharmaceuticals, San Diego and it is under clinical trials

Dithio Compounds
United States Patent 7,820,833
Inventors: Phani Kumar Pullela, Daniel S Sem
These molecules are the first FRET based probes for intracellular thiol quantitation and the molecules were licensed to a company 
in Milwaukee, USA and the work was published in "Analytical Biochemistry".



awards of phani students


 PROJECT AWARDED PROJECT TITLE NAME OF STUDENTS

IEEE Aleyhum July 2014

 
Desalination of water to increase farming water for farmers. First of its kind in the world, developed to reduce suicide deaths of farmers.Rushingwa Grance, Raazia Fathima, Syed Abrar Hussaini

Ideas for India 1st prize, November- 2014

  
Crowd funding for farmers to provide interest and risk free farming loans.  Manideepa, Sai Apoorva, Juhi Joseph 
 Ideas for India 3rd prize , November- 2014Government programs for rural women and for their empowerment Priyanka G, Kavya K 

Ideas  for India, Consolation prize, November- 2014

  
Indian MSME is the most vulnerable class due to globalization and this project tries to provide technological guidance for them. Mrunalini Srinivas, Aishwarya Jakka 
 

CMR IMS Eureka 2K15 December-2015


 

Develop near zero-cost bricks for non-critical structures.

 
Pawani Tungana, Pavan Kondoji , Shruthi Rajendran 

Ideathon 2.0

January-2015 

“Smart Hat” which will record photos & videos “hands-free”.

  
Pavan Kondoji, Shruthi Rajendran 
ideathon 2.0
january 2015 

A platform to auction bank mortgaged houses for obtaining optimum prices for the home owners and elimination brokers and artificial spiking of prices.

  
Prabesh Khadka 
 FKCCI Manthan october 2014

Slim Pizza & uses a Karnataka ‘slocal substitute of tamarind Kokum (Garcinia Indica) for making pizza sauce.

  
 Aishwarya Jakka, Mrunalini Srinivas, Nikita Sara Sunil 
 TP Pitch off  march 2015

“Slim Pizza”. Some of the investors came for competition have taken the CMRIT MOUs for consideration.

  
 Aishwarya Jakka, Mrunalini Srinivas, Nikita Sara Sunilsrishti 
 shristi, 1st prize , swaach bharat , april 2015 Create a reuse for every plastic packaging material, say for example a washing powder sachet will expand to become a garbage bag. An additional secondary use for every packaging material. Tarun Bhaskar 
 KSCST - March 2015 Dismantlable houses for urban & rural slums & use recycled plastic, flyash and sand for building the same.  Prof. Srinivas Reddy, Pranav, Sayak Bhattacharya, Kourshik Reddy, Prof. Joseph Sajan 
Srishti, 1st Prize, Rural Development, April  2015Women Empowerment application.  Rachana K, Kavya K, Chandini Singh 
 Srishti, 1st Prize, Affordable healthcare April 2015

“Sodium polyacrylate” to concentrate gold nanoparticles enabling very cheap lateral flow diagnostic devices.

  
Samata R, Priyanka Purva, Lavanya 
 IEEE UPP mini project- August 2015Developing a Vehicle safety module (VSM) which will inform about an accident  remotely without human interference Pavan R, Anoop CJ, Kushal I 
 Ideas for India November 2015, 1st prizeMultimetal catalyst to clean Bellandur lake &  treat  industrial polluted water Nithin Kumar, Shashank, Avinash,  
Ideas for India November 2015, 2nd prize Polymer- flyash bricks for non-critical structures 

Pavan R

Anoop CJ

Naren M


Ideas for India November 2015, 3rd prize A smart mouth imaging tool Sayak Bhattacharya, Asher John Sathya 
 Ideas for India November 2015, 3rd prizeA neem bandage for plants organic pesticides for vegetable growth Nidhi Poddar, Sujana M, Komal, Pavithra 
 GE Edison challenge January- March 2016 finalistVehicle Safety Module (VSM), finals on March 16th and 17th 2016 Anoop CJ, Kushal I, Pavan R 
Srishti April 2015 CMRIT Overall Runners 64 students from Chemistry department participated with 19 different projects 
Srishti May 2016 CMRIT Overall Runners 200 students with over 50 projects from Chemistry Departments 
 Srishti May 2016 Technical paper presentation, Mechanical: Dismantlable houses: A technology innovation for slums, 2nd prize Koushik Reddy, Sayak Bhattacharya 
Srishti May 2016  Technical paper Oral presentation: Monitoring Tuberculosis Drug Adherence in patients, 3rd prizeAnjali N, Darshan R 
 Srishti May 2016Water tap That- ICT in rural development, 2nd prize Ayush Gupta, Fisba samreen 
 Srishti May 2016ICT in Healthcare,  Indigenous Nucleic Acid Extraction Device from clinical samples, 1st Prize Anjali N, Vandana, Deepika  
Srishti May 2016 Avishkar: Smart MOP, consolation Prize  Chandni Singh, Bhanupriya, Bharat Kumar, Akshita D 
 Srishti May 2016Waste O Mania, Polymer- flyash bricks for non-critical structures, 2nd Prize 

Pavan R

Anoop CJ

Naren M

 
Stanford University UIF September 2016  University Innovation Fellows program, Google’s US $ 4000 scholarshipAsher John Sathya, Priyanka Srivastava, Abhay Rangan 
 Grace Hopper Celebration of Women in Computing India (GHCI) Scholarship Applied July 2016, Selected September 2016Rs 7000 scholarship, All paid (food, accommodation, etc) 3 Days, 2 Nights stay at Taj Vivanta, Bangalore, Free admission to internship & networking meetings  Manogna M, Priyanka Srivastava
 FKCCI Manthan Challenge October 2015, Prize distribution April 2016Veganarke (Prize Rs 50,000/-) Abhay Rangan 
 Indian Innovation Fair, Bangalore, September 2016 Utility of Flyash- Gold Medal 

Pavan R

Anoop CJ

Naren M

Pranav Bhat

Vinay

 
 Arihant Trust- Awards for Rural, Meritorious Girl Students- Applied June 2016, August 2016Total of 1,20,000/- (one lakh twenty thousand rupees) given to ten deserving CMRIT  Rakshita Bhat, Shilpa HV, Kavya S, Manjusha C, Varsha S, Deeksha, Sindhura M Nadgir, Vedashree, Lakshmi Shravya, Ravali 
 Universe Trust Ideas for India 2016Solar Photosynthesis Anindita Ghosh (ECE), Ambadasu Keerthana (ECE), Sagarika Shah (ECE) 
 Water Consolation PrizeUV based Hand-held Bacteria Killer Sai Ganesh (ECE), Rini Jacob (ECE) 
 Water Consolation PrizeSelf Watering Pot Sudarshan MS (TCE), Thejas K Murthy (EEE), Gururaj R (ECE 

Universe Trust Ideas for India 2016

Solar 2nd Prize  
Solar Umbrella Shivani KJ (ISE), Roshan C Thomas (ECE), Deepti Hegde (ISE), Anjali N (ECE) 
Grand challenge Karnataka 2017 Water Aerosol ( 10,00,000 INR grant) mohammed rifas, shubham goyal, vaibhav padmanabha
Grand challenge Karnataka 2017 Purification of  Sewage water ( 10,00,000 INR grant)abhinab mishra, hitesh bhalotia,souptik 





STUDENTS UNDER PROJECT MENTOR SHIP