MyoSim is computer software for modeling the mechanical properties (force, shortening, power output) of striated muscles.

The software models the behavior of half-sarcomeres by extending Huxley-based cross-bridge distribution techniques with Ca2+ activation and cooperative effects. MyoSim can also simulate arbitrary cross-bridge schemes set by the researcher.

You can download all of the software on the Download pageThe easiest way to learn how to use MyoSim is to follow the Getting Started instructions.

MyoSim was developed in the Campbell Lab at the University of Kentucky. All of the code is freely available under the GNU General Public License.

The underlying theory is described in a 2014 article published in the Journal of General Physiology.

Please get in touch if we can be of help or you are interested in collaborating.

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Key points about MyoSim
1) The software is is free to use and very flexible
2) No programming is required
3) You can fit models to your experimental data
4) Tutorials and support are available online
Want to learn more? Go to Getting Started