For Researchers‎ > ‎NEFS Substudies‎ > ‎

Longitudinal Effects on Aging Perinatal Project (LEAP)

Study dates: 2009-2012

Funding provided by NIA (1RC2AG036666-01)

Co-PIs: Eric Loucks, Stephen Buka, and Charles Eaton

 

Overall Aim: To explore how conditions during pregnancy and early life may impact epigenetic alterations and aging processes that could subsequently appear in midlife.

 

Sample: 1487 selected, 400 interviewed

 

Key Documentation

Codebook

Project Summary and Specific Aims

Sources of Questionnaire Items

 

Measures

Home survey

Background (age, race/ethnicity, socioeconomic status)

Physical activity

Health history (family and personal)

Sleep

Childhood experiences

Social networks

Mindfulness

Hostility

Optimism

Food and drinks

 

Clinic survey

Smoking

Cognitive assessment

Depressive symptomatology

Respiratory tract infection

Sexual preference

Self-efficacy

Parental Bonding Instrument

Perceived stress

Altruism scale

Religiosity

Social support

Medications

 

Clinical assessment

Blood pressure

Anthropometric measures (height, weight, waist circumference, hip circumference)

Phlebotomy (lipids, glucose, C-reactive protein, adiponectin)

Carotid Intima Media Thickness (IMT)

Regional adiposity (DXA scan)

 

Additional Documentation

None

 

Publications

Under review