UTC001 MICROCURRÍCULO DE VIROLOGÍA MÉDICA Docente Alvaro Alvarez Coneo Lic Biologia, Bacteriología Uni. Andes, Médico General y Ms Microbiologia, Espec Gest Gerencial U de Cartagena.

UNIVERSIDAD DE CARTAGENA  UNIDAD ACADÉMICA DE MICROBIOLOGÍA    ASIGNATURA  VIROLOGÍA.    DOCENTE: DR ALVARO ALVAREZ CONEO. DOCENTES INVITADOS AL EQUIPO: UNAM, HUNT, WONG, VARGAS, F.DIAZ. VILLAMIL W, B ARROYO, U.WISCOUNSIN, TODAR, KAYSER, CDC, OMS, MIN PROT SOC COL, UDEC, U N CAROLINA, UNAL, ORLANDO BORRE, LIA BARRIOS,  CESAR REDONDO.

CURSO: Agenda para planeación :
 El estudiante aprenderá a utilizar el Project  Planner de Microsoft para aprender a planificar sus actividades y a  implementar sus procesos para optimizar la calidad y el logro de sus objetivos, emejorar su eficiencia y eficacia.Aprenderá a utilizar agendas electrónicas.

 

 

 Microcurrículo  Programa y Planeación con Project Planner : 

 Objetivos:Conocer la biología ,patogénesis, clinica diagnóstico y control epidemiologica de los virus humanos.

Competencias a desarrollar:          SER(APC), Diagnósticas , Argumentativas, Propositivas, Comunicativas, Terapeúticas, Preventivas.

Mapa:               Ecología, biología, epidemiología,  Virus ADN, ARN, oncovirus,   Clínica, Control, Terapéutica, Vacunas, Prevención 

Biologia:     Estructura, microscopia comparada, replicación, transmisión.

Patogénesis: Receptores, antireceptores, invasion intracelular, replicación y sus efectos citopáticos, respuesta inmune de defensa y dañina, evasión , citoquinas, eosinofilia, lesiones por aparatos y sistemas

Epidemiología y control

Evaluación de Estilos de aprendizaje, conocimientos previos Test de entrada verbal o escrito

    Metodología pedagógica: Aprendizaje significativo, conceptual. Constructivismo. Metodología de la investigación.

      Trabajos en casa: Lecturas complementarias de textos y artículos científicos, solución de problemas, ABP, Mentefactos y Mapas Conceptuales.  Elaboración de Proyecto de Investigación,

        Guía texto

        Diapositivas

        Resúmenes

        Historias clínicas

        Artículos científicos

        ABP

        Preguntas y casos problema

        Videos:   VER  1.KAYSER  VIDEOS DE VIROLOGIA

         

        Search YouTube

        VIDEOS VIRUS Y VIROLOGIA MEDICA:

        https://www.youtube.com/results?search_query=virologia+medica

        1.BIOLOGIA MOLECULAR

        2.INMUNOLOGÍA

        3.VIROLOGÍA

        3.1.UTC01
        3.2.UTC02
        3.3.
        OTROS:

        4.BACTERIOLOGÍA

        5.MICOLOGÍA

        6.PARASITOLOGÍA

        7.INFECTOLOGÍA

        8..ECOLOGIA
         

         

         

         

         

         

        UdeC. Moodle

        Evaluaciones

        Diccionario de microbiología

        Tutorías

        Instrucciones Laboratorio

        Informes de Laboratorio

        /

        CURSO BÁSICO DE VIROLOGÍA MÉDICA

        PROYECTO DOCENTE

        Proyecto docente 2017


        Proyecto VIROLOGIA md 2P 2015 ED 230815 5030PM julio cisnero wwwaaccom.xls


        TABLA DE CONTENIDOS   ( SILLABUS)

        Generalidades.

        Virus ADN.

        Virus ARN.

        Virus  ONCOGÉNICOS

        Infecciones lentas:

          1. Por virus convencionales

          2. Priones

        Laboratorios.

        Seminarios

        Biblioteca de Microbiología e Inmunología.

        Evaluaciones. Calificaciones.

        SIGUC. Encuestas de calidad. Buzón de sugerencias.




        ADC UTC

        Objetivos  Generales  de la Clase
         Conocer la virología médica, su importancia epidemiologica y sus  fuentes de información
         Competencias

        Competencias del ser: A P C    Asistir a todas las clases  , Presentacion personal excelente, Conducta humana de respeto,  respetuosa de la normatividad laboral para disminuir los riesgos.

        Fomentar competencias del ser indispensables  como bases para el desarrollo de competencias del saber y saber hacer.Estudios familiares de marketin. Motivación. DOFA personal. Proyectos definidos.  Organización de la agenda personal. Nutrición  balanceada para ejecutivos. Administración optima del tiempo para Trabajo-descanso -trabajo-sueño. Responsabilidad. Etica. Tolerancia. Saber escuchar. Respeto a los demás. Uso correcto y mejoramiento contínuo del idioma. Aprender Ingles, Frances, Chino-Mandarín, Aleman y Ruso.  Aprender a trabajar en equipo.
        Competencias del Saber:
        Conocer Estructura, genetica,morfología,  taxonomía, ecología, transmisión, replicación viral, patogénesis, clínica
        Objetivos  Específicos de la Clase
         Conocer las principales familias virales ,  estructura viral, su replicación, patogénesis, respuesta inmune , patogénesis, diagnóstico, control terapéutica.
         Competencias
        Desarrollar competencias argumentativas propositivas, comunicativas,
         Competencias del saber hacer:
        Diagnósticas: Diagnóstico clínico y de laboratorio
        Terapéuticas. Conocer los procesos de mutaciones y generacion de resistencia, resistencia cruzada y reversión de resistencia por segunda mutacion.Seleccionar el medicamento adecuado. Valorar riesgos de efectos secundarios
        PROGRAMA DEL CURSO DE VIROLOGÍA CLÍNICA:
        Específicos de la Clase: 
        Programa de la clase  
        Biología-Patogénesis- Clínica-Diagnóstico-Control-Epidemiología.
        Mapa de la clase 
        Taxonomía, estructura, genética,  ecología, transmisión, replicación, efecto citopático,  patogénesis, clínica, diagnóstico, terapeútica,  epidemiología.
        Evaluación de conocimientos previos    prerrequisitos para la clase
         Acidos nucleicos, mutación, replicación, transcripción,
        Metodología pedagógica 
        Clases constructivistas con orientación del docente y participación significativa de los estudiantes, para el desarrollo de sus competencias
        GUÍA:
        Los estudiantes  estudian el tema de clase previamente para poder hacer su participación en clase elaboran PVCs , hacen preguntas para el  quiz de grupo. Se les informa en el programa el tema a tratar
         
        Texto sobre tema de clase para leer previamente y posteriormente a la clase 
         
         
         
         

        AUDIO DE DIAPOSITIVAS:

        VIDEO DE CLASE:
         
        VIDEOS PARA EL CURSO DE VIROLOGIA -LINKS

          KAYSER   VIDEOS  DE VIROLOGIA

        http://student.ccbcmd.edu/~gkaiser/MYANIMATIONS.pdf

         
         
        Plan de trabajo
         
         
        Trabajo Independiente post clase
         
        Resúmenes  en mf  mc:
        El estudiante debe bajar el CMAPTOOLS 5.03  (ver link http://cmap.ihmc.us  en esta pagina columna derecha cuarto inferior)
        para elaborar mentefactos para mejorar la comprensión de conceptos y mapas conceptuales para ver la elaboración de los mismos y posteriormente
        Debe conmsultar en las fuentes recomendadas los videos sobre los temas de clase que le ayuden a mejorar la comprensión de loc conceptos expuestos en el material didáctico.
         
        Trabajo Independiente post clase
         

        Historias clínicas 

        ABP 

        Preguntas y casos problema 

            
                                  
        Artículos científicos
        Links
        UDEC MOODLE
        Bases de datos
        DICCIONARIO DE MICROBIOLOGIA
         
        Evaluaciones por Competencias:  A, P, C , PVC,  PVI,  QG, QI, QP ETC, RTEE, RTEV,   HC,    Revisión por Aparatos y Sistemas (RAPS),  ABP PIAS, TALLER, RTE 
         
        A  (ASISTENCIA), P(PRESENTACION, C(CONDUCTA).-Competencias del SER que se evalúan diariamente.
         
        PVC: Preguntas Verbales en clase. Realizadas por estudiantes o docentes, para verificar comprención y memorización dela clase anterior o actual y desarrollar las competencias comunicativas y de procesamiento de conceptos para elaborar preguntas.
         
        QG: Quices de grupos. Se realizan diariamente para repasar la clase, verificar la comprensión de la misma, desarrollar competencias comunicativas escritas conceptuales de edición de preguntas (5 a 50). Duración 5 a 30 minutos.  
         
        QI: Quices individuales  o en Pareja QP para verificar comprención , memorización, desarrollo de competencias.
         
        PIAS:Preguntas de Investigación para actualización en tópicos específicos de biología molecular para mejorar la comprensión de la patogénesis a nivel molecular.  Se le dan  al estudiante los temas a investigar en el libro texto y deben complementarlos en revistas cientificas y en las bases de datos de la universidad. Hacen las diapositivas con mapas conceptuales  y presentan en 10 minutos sus conceptos importantes. Cada uno de los cinco grupos tiene sus respectivas PIAs.
        Se evalúa :   competencias comunicativas,verbal, escritura,  artísticas (diapositivas),manejo de mentefactos y mapas conceptuales, argumentativas, propositivas, interpretativas, manejo de tiempo, comprensión del artículo,evaluación estadística, traducción, trabajo de equipo, presentación .
        PIAS  1ER PERIODO  2011  4SEM MD :
         
         
         
        RTE(Revisiones de Temas por Estudiantes. Equivalentes a los Seminarios). Desarrollo de competencias comunicativas orales y escritura, revisión y actualización de conocimiento .
        Se asignan temas, o artículos científicos específicos , para su lectura, comprensión, elaboracion de mentefactos y mapas conceptuales que resuman y relacionen los conceptos claves  . Cuando el tema es una enfermedad infecciosa, debe conocer la taxonomía, estructura del virus, cápside, genoma, antireceptor, receptor, factores de virulencia, ciclo, replicación ,  ecologia, transmisión, patogénesis, ECP, respuesta inmune, evolución de la enfermedad, síntomas y signos, clínica, diagnóstico clínico y de laboratorio , diagnóstico diferencial, Epidemiología en Colombia, Boletines del SIVIGILA, , CONTROL, bioseguridad, desinfección,   Antivirales, tratamiento segun la OMS, dosis, duración, vías de administración, pruebas de sensibilidad alergica, interacciones medicamentosas, contraindicaciones, sinergia y antagonismo, terapia HAART,Resistencia, Medicina alternatiova, homeopatia,  VACUNAS-PAI. Prevención epidemiológica. Medidas profilacticas pertinentes. Debe presentar un caso clínico de ilustración del marco teórico y un artículo científico que actualice uno de los conceptos claves mas importantes del tema, Exponen 20 minutos, hacen 10 minutos de PVC y deben entregar trabajo escrito grabado en DVD (haga permanentemente backups padre hijo nieto padre hijo nieto y actualice antivirus). El trabajo escrito debe contener PS-TX-IM-MF-MC-MM-EPCOL-10-HC, 10-AC, DP-RTEV-CS-BGF-( un objetivo es el desarrollo de competencias diagnosticas, terapéuticas, leptoescritura y trabajo en equipo : 
        RTEV:    
        GRUPO 1.ENF.VIRAL EN PIEL Y MUCOSA:                         VER UTC No.:
        GRUPO 2.ENFERMEDAD VIRAL DE CCCCC (CABEZA, CARA, CUERO CABELLUDO, CUELLO,  CRANEO),
        GRUPO 3. ENF.VIRAL RESPIRATORIA.                               VER UTC 
        GRUPO 4.SIST CARDIOVASCULAR 
        GRUPO 5 SISTEMA  SANGUINEO ENDOTELIO, MEDULA, BAZO .ENFERMEDADES VIRALES QUE AFECTAN PLAQUETAS-ENDOTELIO-HEMORRAGICAS. VER UTC
        GRUPO 4.SISTEMA ENDOCRINO: Parotidas, páncreas, testículos,
        GRUPO 5.virus que afectan apto y SISTEMA DIGESTIVO: BOCA ESOFAGO ESTOMAGO INTESTINO HIGADO  HEPATITIS, A, B, C, D, E, F, G, H,  TTV,      VER  UTC.    
        GRUPO 6.VIRUS EN TRANSITO TGI Y V PRODUCTORES DE EDA.     VER UTC 
        GRUPO 7.virus que afectan apto y SISTEMA RENAL , Y VIAS  Urinariasl.
        GRUPO 8.Enfermedades virales de SISTEMA GENITAL  transmisión sexual  EVTS, LOCALIZADAS:VHS1, HPV, CMV, HBV, HCV, KHSV/HHV-8, HIV, HTLV,MOLUSCO CONTAGIOSO, ADENOVIRUS, TTO OMS. 2.GENERALIZADAS: VHA, VHE, VHD, VIH, HTLV I/II, CMV.  
        GRUPO 9.ENF VIRAL CONGENITAS INTRAUTERINAS, EMBARAZO: RUBEOLA(Familia Togaviridae), CMV, VIH , VZV, PARVOVIRUS B-19, V.  LCM..     PERINATALES(infeccion durante el parto) HSV, VZV, HPV, VIH.    TORCHS.  OTRAS.                    VER UTC
        GRUPO 10. VIRUS QUE AFECTAN SISTEMA MUSCULAR     POLIO
        GRUPO 11  VIRUS QUE AFECTAN SISTEMA OSTEOARTICULAR   POLIO
        GRUPO 12 . Enfermedades virales que afectan SNC (Cap 30 Lesly Collier pag 222.). GRUPO 1: Infecciones agudas que afectan directamente el SNC: 1.Meningitis(inflamación de meninges con o sin cierto grado de ENCEFALITIS) por Enterovirus (ECHO, Coxsakie A, B, Enterovirus 70,71, Poliovirus, Parotiditis, CorioMeningitis Linfocitaria, Enfermedad de Louping,   VEB, VHS-2, VVZ,  Poliomielitis.   
        GRUPO 2: Enfermedades agudas del SNC no causadas directamente por un virus  
        GUPO 3: Enfermedades crónicas letales  causadas por reacciones generales  anormales  contra virus convencionales o PIONES .              
         
        GRUPO 11.VIRUS ONCOGENOS,  HEPATOCARCINOMA, LEUCEMIA, CARCINOMA DE CERVIX, VEB LINFOMA BURKIT , SARCOMA DE KAPOSI,  MIRANDA,                                           VER UTC.  
        GRUPO 12 ENFERMEDADES EMERGENTES Y REEMERGENTES, ENFERMEDADES VIRALES ZOONOTICAS
        GRUPO 13 VACUNAS-PROFILAXIAS-BIOSEGURIDAD




         
        RTEE: PS-TX-IM-RE(MF-MC-MM)-ICB(10HC(+2ABP)-10AC)-SPRI)- EPIDEMIOLOGIA BOLETINES  INAS SIVIGILA   DP-CS-BFG:
        1.0.PS=Presentacion de acuerdo a las normas de Incontex. Titulo autores docente universidad fecha de edicion profacion introduccion agradecimientos ìndice de contenido , de graficas y tablas
        2.0.TX= Textos= contenido. Fichas bibliográficas organizadas coherentemente de acerdo al a tabla de conmtenidos. Norma Icontex
        3.0.IM= imágenes.  De cada  virus, Patogénesis, ECP,lesión tisulares,  de signos, radiológicas, ecográficas, de hallazgos en  autopsia.
        4.0.RE=resúmenes 
        4.1En mentefactos(CMAPTOL),
        4.2.En Mapas Conceptuales(CMAPTOOL),   Mapas Mentales  (FreeMind-ver Pagina del CREAD)
        5.0.IBC: Integración de Básica con Clínica.
        5.1.ABP , 1 EJERCICIO DE APRENDIZAJE BASADO EN PROBLEMAS CON 1 HC. LA PRESENTADA EN EL SEMINARIO.
        5.2.HC: 10-HISTORIAS CLÍNICAS,  
        5.3.AC: 10-ARTICULOS CIENTIFICOS )
        5.4.ATD    Algoritmos de Toma de Decisiones para diagnóstico y terapéutica.
        6.0. EP=EPIDEMIOLOGIA EN COLOMBIA. SIVIGILA. INS. PROCESO DE REPORTE OBLIGATORIO AL SIVIGILA: Por ejemplo de DE FIEBRE AMARILLA, DENGUE, RABIE, ETC. 
        7.0. DP=Diapositivas de clase -SEMINARIO-RTEV
        8.0. CS=Conclusiones
        9.0. BF=Bibliografía
        10.0 creditos a las imagenes (bibliografia)
        10. DVD=Presentación al docente en DVD. Compartir copias con los compañeros de los otros grupos de trabajo.
        11. Prevención de pérdida de archivos: Sacar a lo largo del trabajo Backups (copias) ( en otro disco o memoria o CPU, o discos virtuales ADRIVE,  Gmail, Hotmail) de seguridad por el sistema Padre-Hijo-Nieto, actuaizar antivirus.
         
        UTC: Unidad de Tema de Clase
         
         REVISION DE TEMAS POR ESTUDIANTES  EXPOSICIONES VERBALES (RTEV) Y   TRABAJOS ESCRITOS (RTEE ) 
        Temas y Guia de trabajo
        1.Virus y Enfermedades virales que producen lesion en PIEL Y MUCOSAS    y diagnóstico diferencial. 
        2.Virus y Enfermedades virales que producen lesion en Cabeza, Craneo, Cuero Cabelludo y Cuello  (CCCCC) y diag diferencial
        3.Virus y Enfermedades virales que producen lesion en SISTEMA RESPIRATORIO  y diagnóstico diferencia
        4.Virus y Enfermedades virales que producen lesion en sistema cardio vascular   y diagnóstico diferencia
        5.Virus y Enfermedades virales que producen lesion en SISTEMA SANGUINEO Y ENDOTELIO VASCULAR  y diagnóstico diferencia
        6.Virus y Enfermedades virales que producen lesion en SISTEMA DIGESTIVO  y diagnóstico diferencia
        7.Virus y Enfermedades virales que producen lesion en SISTEMA RENAL Y VIAS URINARIAS  y diagnóstico diferencia
        8.Virus y Enfermedades virales que producen lesion en SISTEMA GENITAL (ETS, ENFERMEDADES CONGENITAS, DURANTE EL EMBARAZO,    PERINATALES, )  y diagnóstico diferencia
        9.Virus y Enfermedades virales que producen lesion en SISTEMA OSEO    y diagnóstico diferencia
        10.Virus y Enfermedades virales que producen lesion en SISTEMA MUSCULAR   y diagnóstico diferencia
        11.Virus y Enfermedades virales que producen lesion en SISTEMA NERVIOSO PERIFERICO  Y CENTRAL y diagnóstico diferencia
        12.Virus y Enfermedades virales que producen lesion en SISTEMA ENDOCRINO   y diagnóstico diferencia


         

        Familias Virales de Interés Médico





        Virología ETC 2P Nov2013



         

        Virología ETC Timothy Murray. Alumnos 1P 2015

         
        UTC: Unidad de Tema de Clase
         
        AGENDA: El estudiante aprenderá a utilizar el project planner de micrsoft para aprender a planificar sus actividades y a  implementar sus procesos para optimizar la calidad y el logro de sus objetivos, emejorar su eficiencia y eficacia.Aprenderá a utilizar agendas electrónicas.
         
        TUTORIAS
        INSTRUCCIONES LAB

        INFORMES LAB
         1. Pprocedimientos de diagnostico en VIROLOGÍA CLÍNICA. Laboratorio clinico, Paraclinicos: Laboratorio de patologia  (biopsia, autopsia), Imagenologia: RX, TAC, RNM, Ecografia, Ecocardiograma,  
         2.Diagnóstico de enfermedades VIRALES que producen lesion en PIEL Y MUCOSAS    y diagnóstico diferencial. 
        3..Diagnóstico de enfermedades VIRALES que producen lesion en Cabeza, Craneo, Cuero Cabelludo y Cuello  (CCCCC) y diag diferencial
        4..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA RESPIRATORIO  y diagnóstico diferencia. PRACTICA EN LABORATORIO DE VSR.
        5..Diagnóstico de enfermedades VIRALES que producen lesion en sistema cardio vascular   y diagnóstico diferencia
        6..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA SANGUINEO Y ENDOTELIO VASCULAR  y diagnóstico diferencia
        7..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA DIGESTIVO  y diagnóstico diferencia. PRACTICA EN LABORATORIO DE ROTAVIRUS.    AgSHB      AcHB.
        8..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA RENAL Y VIAS URINARIAS  y diagnóstico diferencia
        9..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA GENITAL (ETS, ENFERMEDADES CONGENITAS, DURANTE EL EMBARAZO, PERINATALES, )  y diagnóstico diferencia
        10..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA OSEO    y diagnóstico diferencia
        11..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA MUSCULAR   y diagnóstico diferencia
        12..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA NERVIOSO PERIFERICO  Y CENTRAL y diagnóstico diferencia
        13..Diagnóstico de enfermedades VIRALES que producen lesion en SISTEMA ENDOCRINO   y diagnóstico diferencia
         14.DIAGNOSTICO DE ENFERMEDADES VIRALES QUE PRODUCEN CANCER ,   VPH    COILOCITOSIS  P16 INK 4A,  
          
         
        TALLER:
         

        AGENDA:

         

         

        TUTORIAS

        UDEC MOODLE

         

        INSTRUCCIONES LAB
        INFORMES LAB
         
         
         
          

         Bibliografía  

        1.Leslie Collier, John Oxford. Virología Humana. 3era edición.McGrawHill 2008.

        2.Manuel Vargas Córdoba. Virología Médica. U.Nacional. 2016. 2da edición.

        3.MANDEL,  DOUGLAS, BENNET , ENFERMEDADES INFECCIOSAS  3 TOMOS. 6TH EDIT 2006. 

        3.Timothy J. Bos,  Microbiologia  y Enfermedades Infecciosas  USML 2008, McGraw Hill

        4.Francisco Diaz  Microbiología de las Enfermedades Infecciosas.2009. CIB.Medellin.

        5.Angela Restrepo . Enfermedades Infecciosas. Fundamentos de Medicina . CIB. 4ed 2003.

        6.Patrick Murray Microbiología Médica 7 ed 2016

        7.Mimms  Microbiología Médica 2004

        8.Ernts Jawetz Microbiologia Médica. Manuales Modernos. 28 ed 2016.

        9.Luis Fidel Avendaño .Virología clínica.   Editorial Mediterraneo. Chile, 2ed 2016. Valor $157.000oo

        10.N.J.Dimmock. Introduction to Modern Virology. 4ed 2007 https://docs.google.com/a/alvaroalvarezconeo.com/viewer?a=v&pid=explorer&chrome=true&srcid=0B5GYbcCmYHGdYThkNDdmNDItNGNiNy00YjY5LTk0MjctMDZmMzY2YmMwZmY1&hl=en

         10 Robbins    Patología Clínica

        11. Unam. Manual departamental de Virología, curso 2009 - 2010

        12.  Comité Internacional de Taxonomía de Virus -en inglés International Committee on Taxonomy of Viruses (ICTV).

        http://www.ictvonline.org/virusTaxonomy.asp?bhcp=1


        http://es.wikipedia.org/wiki/Comit%C3%A9_Internacional_de_Taxonom%C3%ADa_de_Virus     

         The origin of ICTVdB, webpage, retrieved 22nd June 2006

         

        13. RICHARD HUNT, MARGARET HUNT, PATRICK MURRAY. VIROLOGIA ON LINE.
        UNIVERSIDAD SOUTH CAROLINA.         
        MICROBIOLOGIA    


        INMUNOLOGIA   

        VIROLOGIA

        BACTERIOLOGIA
        MICOLOGIA
        PARASITOLOGIA
        INFECTOLOGIA, PATOGENESIS MICROBIANA, INMUNOPATOLOGIA,  POR APARATOS Y SISTEMAS  DIAGNOSTICO DIFERENCIAL
        CHAPTER ONE
        INTRODUCTION

        PIEL Y MUCOSAS
        CHAPTER FOUR
        INFECTIONS OF THE SKIN AND ITS APPENDAGES, MUSCLE AND BONE
         CCCCC CABEZA CRANEO CUERO CABELLUDO Y CUELLO
        CHAPTER TWO
        UPPER RESPIRATORY TRACT INFECTIONS AND INFECTIONS OF THE HEAD AND NECK

        RESPIRATORIO
        CHAPTER TWO
        UPPER RESPIRATORY TRACT INFECTIONS AND INFECTIONS OF THE HEAD AND NECK
        CHAPTER THREE
        LOWER RESPIRATORY TRACT INFECTIONS

        CHAPTER FIVE
        MYCOBACTERIAL INFECTIONS
        CARDIOVASCULAR Y SANUINEO Y ENDOTELIO VASCULAR

        SISTEMA DIGESTIVO , GASTROINTESTINAL, BOCA, ESOFAGO, INTESTINO DELGADO, HIGADO, PANCREAS
        CHAPTER SIX
        GASTROINTESTINAL TRACT INFECTIONS

        CHAPTER SEVEN
        URINARY TRACT INFECTIONS
        TEST YOUR KNOWLEDGE


        CHAPTER EIGHT
        SEXUALLY TRANSMITTED DISEASES



        CHAPTER TEN 
        CENTRAL NERVOUS SYSTEM INFECTIONS
        http://www.microbiologybook.org/Infectious%20Disease/CNS%20infections.htm

        CHAPTER ELEVEN
        INFECTIOUS DISEASE EMERGENCIES



         
        14. institute for molecular virology U.Winscousin
         
        15.http://www.virology.net/
        16.http://www.virology.net/Big_Virology/BVHomePage.html

        18.    CLINICAL AND DIAGNOSTIC VIROLOGY.   MUY BUENO. COMPRAR.      http://docs.google.com/a/alvaroalvarezconeo.com/fileview?id=0B5GYbcCmYHGdMTNhNDFjYmEtYWRiMS00MWI4LTkwM2EtMmNkMjhmZDA4NjNk&hl=en

        19. N.J.Dimmoc.  INTRODUCTION TO ODERN VIROLOGY. 4 ed 2007.

        https://docs.google.com/a/alvaroalvarezconeo.com/viewer?

        a=v&pid=explorer&chrome=true&srcid=0B5GYbcCmYHGdYThkNDdmNDItNGNiNy00YjY5LTk0MjctMDZmMzY2YmMwZmY1&hl=en

        20.-ASOCIACION PANAMERICANA DE INFECTOLOGIA

        http://www.apinfectologia.org/?module=noticias_congreso

        21. DEREK WONG´S VIROLOGY COURSE



        This site contains notes on various aspects of virology. It is designed as a study aid for undergraduate and postgraduate students. Besides general information on virology and individual viruses, this site also contains suggested answers to some likely examination questions in virology as well as some ready-to-use slide sets. My name is Derek Wong and I am a medical virologist working in Hong Kong. I worked in the laboratory that detected the first ever human avian influenza infection in May 1997 and was involved during the avian influenza crisis later that year, and the SARS crisis in 2003. Previously I have worked in the U.K. I have an M.Sc degree in virology from the London School of Hygiene and Tropical Medicine as well as membership of the Royal College of Pathologists MRCPath(UK). I am extensively involved in teaching virology to medical students and laboratory technologists. I would like to dedicate this site to my mother Elaine Li Yee Ling.


        General Information

        Individual Viruses

        Exam Questions and Answers

        Ready-to-use slide sets

         


        Mail to: derekwong28@hotmail.com

        All the Virology on the World Wide Web

            

        22.   CURSO DE VIROLOGIA UNAM 2010.

        25. SITIOS DE INTERNET CON INFORMACIÓN CONFIABLE SOBRE VIROLOGÍA MÉDICA General:

        www.cdc.gov

        www.who.int

        www.virology.net

        Particular

        25.5. Ébola

        http://www.who.int/csr/disease/ebola/es/

        http://www.cdc.gov/vhf/ebola/

        25.6. INS Protocolos de notificación

        http://www.ins.gov.co/lineas-de-accion/Subdireccion-Vigilancia/sivigila/Paginas/protocolos.aspx

        25.7.Hepatitis

        www.hepnet.com

        25.8. Herpes

        www.herpeszone.com

        25.9. Esquemas de Vacunación

        http://www.minsalud.gov.co/salud/Paginas/EsquemasdeVaunaci%C3%B3n.aspx

        http://revistainfectio.org/site/portals/0/ojs/index.php/infectio/article/viewFile/521/500

        25.10. Sida

        www.aidsinfonet.org

        25.11 Fiebre Amarilla

        http://www.msal.gov.ar/observatorio/images/stories/documentos_institucional/materiales-didacticos/2-3-3-F-modulofamarilla.pdf

        http://www.minsalud.gov.co/comunicadosprensa/documents/fiebre_amarilla.pdf


        Toda la virología en el Web

        26.    http://www.journals.elsevier.com/virology/recent-articles/

             http://www.journals.elsevier.com/virology/open-access-articles/

                http://www.hindawi.com/journals/av/


        27. EGI ETV 2012-2021

        http://www.proyectomalariacolombia.co/files/msps/EGIETVNacionalversion26demarzode2013.pdf

         

        Kenneth TodarVirology. U.Wiscounsin.

        Introduction to Virology: Bacteriophages             123

        Animal Viruses     1.2 The Big Picture Book of Viruses  provide images and links and describes viral morphology and classification  www.virology.net/Big_Virology

        RNA Viruses

        Picornaviridae
        includes enteroviruses, Hepatoviruses (hepatitis A), rhinoviruses, foot and-mouth disease virus

        Togaviridae
        includes rubella

        Flaviviridae
        includes "hepatitis C-type virus" and dengue

        Retroviridae
        Includes HIV, FLV, and MMTV

        Paramyxoviridae
        measles, mumps

        Rhabdoviridae
        rabies, vesicular stomatitis virus

        Orthomyxoviridae
        influenza

        Filoviridae
        Marburg and Ebola

        Bunyaviridae
        Hanta virus

        Arenaviridae
        Includes lymphocytic choriomeningitis virus

        Coronavirus
        SARS


        DNA viruses

        Adenoviridae
        common cause of the common cold

        Herpesviridae
        includes HSV, VZV, Cyotmegalovirus and Epstein-Barr Virus

        Poxviridae
        smallpox, variola, cowpox (Vaccinia)

        Papovaviridae
        polyoma and human papilloma virus

        Hepadnaviridae
        Hepatitis B Virus

        Parvoviridae
        Canine parvovirus

         




        Human Diseases caused by Viruses

        Acute hemorrhagic conjunctivitis - Coxsackie A-24 virus (Picornavirus: Enterovirus), Enterovirus 70 (Picornavirus: Enterovirus)

        Acute hemorrhagic cystitis - Adenovirus 11 and 21 (
        Adenovirus)

        AIDS / Acquired Immune Deficiency Syndrome - human immunodeficiency virus (
        Retrovirus)

        Bronchiolitis - Respiratory syncytial virus (
        Paramyxovirus), Parainfluenza virus (Paramyxovirus)

        California encephalitis - California encephalitis virus (
        Bunyavirus)

        Cervical cancer - human papilloma virus (
        Papovavirus)

        Chickenpox - varicella zoster virus (
        Herpesvirus)

        Colorado tick fever - Colorado tick fever virus (
        Reovirus)

        Conjunctivitis - Herpes Simplex Virus (
        Herpesvirus)

        Cowpox - vaccinia virus (
        Poxvirus)

        Croup, infectious - parainfluenza viruses 1-3 (
        Paramyxovirus)

        Dengue - dengue virus (
        Flavivirus)

        "Devil's grip" (pleurodynia) - Coxsackie B (
        Picornavirus: Enterovirus)

        Eastern equine encephalitis - EEE virus (
        Togavirus)

        Ebola hemorrhagic fever - Ebola virus (
        Filovirus)

        Gastroenteritis - Norwalk virus (
        Calicivirus), rotavirus (Reovirus), or various bacterial species

        Genital HSV - Herpes Simplex Virus (
        Herpesvirus)

        Gingivostomatitis - HSV-1 (
        Herpesvirus)

        Hantavirus hemorrhagic fever / Hantaan-Korean hemorrhagic fever - Hantavirus (
        Bunyavirus)

        Hepatitis:
        Hepatitis A - hepatitis A virus (
        Picornavirus: Enterovirus)
        Hepatitis B - hepatitis B virus (
        Hepadnavirus)
        Hepatitis C - hepatitis C virus (
        Flavivirus)
        Hepatitis D - hepatitis D virus (Deltavirus)
        Hepatitis E - hepatitis E virus (
        Calicivirus)

        Herpangina - Coxsackie A (
        Picornavirus: Enterovirus), Enterovirus 7 (Picornavirus: Enterovirus)

        Herpes, genital - HSV-2 (
        Herpesvirus)

        Herpes labialis - HSV-1 (
        Herpesvirus)

        Herpes, neonatal - HSV-2 (
        Herpesvirus)

        HIV - human immunodeficiency virus (
        Retrovirus)

        Infectious myocarditis - Coxsackie B1-B5 (
        Picornavirus: Enterovirus)

        Infectious pericarditis - Coxsackie B1-B5 (
        Picornavirus: Enterovirus

        Influenza - Influenza viruses A, B, and C (
        Orthomyxovirus)

        Keratoconjunctivitis - Adenovirus (
        Adenovirus), HSV-1 (Herpesvirus)

        Lassa hemorrhagic fever - Lassavirus (
        Arenavirus)

        Marburg hemorrhagic fever - Marburg virus (
        Filovirus)

        Measles - rubeola virus (
        Paramyxovirus)

        Meningitis, aseptic - Coxsackie A and B (
        Picornavirus: Enterovirus), Echovirus (Picornavirus: Enterovirus), lymphocytic choriomeningitis virus (Arenavirus), HSV-2 (Herpesvirus)

        Mononucleosis - Epstein-Barr virus (
        Herpesvirus)

        Mumps - mumps virus (
        Paramyxovirus)

        Pharyngitis:
        Respiratory Syncytial Virus (
        Paramyxovirus: Pneumovirus)
        Influenza Virus (
        Orthomyxovirus)
        Parainfluenza Virus (
        Paramyxovirus)
        Adenovirus (
        Adenovirus)
        Epstein-Barr Virus (
        Herpesvirus)

        Pleurodynia - Coxsackie B (
        Picornavirus: Enterovirus)

        Pneumonia, viral - respiratory syncytial virus (
        Paramyxovirus), CMV (Herpesvirus)

        Polio, Poliomyelitis - Poliovirus (
        Picornavirus: Enterovirus)

        Progressive multifocal leukencephalopathy - JC virus (
        Papovavirus)

        Rabies - rabies virus (
        Rhabdovirus)

        Roseola - HHV-6 (
        Herpesvirus)

        Rubella - rubivirus (
        Togavirus)

        Severe Acute Respiratory Syndrome (SARS) - a human coronavirus (
        Coronavirus)

        Shingles (zoster) - varicella zoster virus (
        Herpesvirus)

        Smallpox - variola virus (
        Poxvirus)

        Urethritis - Herpes Simples Virus (
        Herpesvirus)

        Varicella - varicella zoster virus (
        Herpesvirus)

        Western equine encephalitis - WEE virus (
        Togavirus)

        Yellow fever - Yellow fever virus (
        Flavivirus)

        Zoster - varicella zoster virus (
        Herpesvirus)                        

        30.  The Common Cold                      Websites for the Common Cold
        Cardiff(UK): General Common Cold Information
        NIAID: The Common Cold
        Quanta-Gaia: Beating Colds and Flu
        Stanford Coronavirus Group

         

        31. Influenza                               Influenza Websites
        CDC: Avian Influenza Infections in Humans
        CDC: Influenza (Flu).
        CDC: The Influenza Viruses
        Stanford: The Influenza pandemic of 1918
        University of Capetown: Influenza
        University of Maryland: Avian Influenza Virus Program
        WHO: Avian Influenza

        32.N SARS (Severe Acute Respiratory Syndrome)

        33. Measles Measles Websites
        CDC National Immunization Program: Measles
        CDC Yellow Book: Measles (Rubeola)
        MedlinePlus: Measles

        34.Mumps

        35. Rubella (German Measles)                                                    CDC website: Rubella (German Measles) and the                                                              NIH website: Rubella (German Measles)

        36.Varicella (Chickenpox and Shingles)

        37. Polio (poliomyelitis)

        38. Viral Hepatitis Viral Hepatitis Resources
        CDC: Hepatitis Vaccines
        CDC: Viral Hepatitis
        MedlinePlus: Hepatitis
        National Center for Infectious diseases: Viral Hepatitis Resource Center: Take a Closer Look
        National Digestive Diseases: Viral Hepatitis: A through E and Beyond
        Department of Health and Human Services: Viral Hepatitis

        39.Herpes Viruses  Herpes Links
        CDC Epstein-Barr Virus and Infectious Mononucleosis
        CDC Genital Herpes (Fact Sheet)
        Department of Health and Human Services - Genital Herpes
        Expert Views in Molecular Medicine: Epstein-Barr Virus (EBV) infections in normal healthy virus carriers
        Genital Herpes, NIAID Fact Sheet
        Genome News Network: Small Genes May Help Mono Virus Hide in Humans
        Herpes - Minnesota Dept. of Health
        Science News Online.: New studies suggest how Epstein Barr virus infects and persists
        University of South Carolina School of Medicine: Herpes Viruses

        40.Smallpox (Variola)

        41.Rabies        Web-rabies
        CDC National Center for Infectious Diseases: Rabies
        Immunization Action Coalition: Rabies Information
        ACIP: Rabies Prevention
        eMedicine - Rabies : Article by Mark Merlin, DO, FACEP
        WHO: Rabies Vaccines                                                        http://www.virology.net/Big_Virology/


        12-31-09

        42.  VACUNAS (Ejercicio realizado en 2007).

         
         
        19.Artículos científicos
        Links
        44.Bases de datos  U de C:
        EBSCO
        HINARY
        SCIENCEDIRECT
        Freemedical journals
        Pubmed
         
         
        45. DICCIONARIO DE MICROBIOLOGIA
         

         46.. Bioquímica y Biología Molecular en línea. Instituto de Química, UNAM. Dr. Edgar Vázques Contreras, 2003

         Francisco Díaz  Microbiología de las enfermedades infecciosas. 2007

         

        47. OPS. Tratamiento de las enfermedades infecciosas 2007-2008:

         

        http://docs.google.com/a/alvaroalvarezconeo.com/fileview?

        id=0B20ap4mysHV8YTA5MmFlMWEtZjJlNS00MjkwLWFhNGYtOWUzNzY5ZDY5NjIx

         
         
         
         
         50.Recursos y Bases de Datos de Virología General
        • 50.1.   26.The Viremia Page - La Página de la Viremia de Alistair Kidd, Departamento de Virología de la Universidad de Umeå, Suecia. La página está diseñada de modo interactivo para los estudiantes en el campo de la virología médica. Hay enlaces de interés, cuidadosamente seleccionados a otras WWW. El material interactivoe stá escrito en  Javascript.
        • 50.2.     27. Medical Virology - de Human Virology Educational Series : 1997-1998 por JN-Internatioanl, Inc. esta WEB contiene descripciones básicas de ciertas infecciones víricas.
        • 450.3.   28. Term database for human virology - Base de datos de términos en virología human - si no conoce lo que significan algunas palabras sobre virología, ésta es su página. Editada por Jonas Blomberg en Lund, Suecia.
        • 50.4.     29. Virologia y Analisis Clinicos para Enfermeria - Virología y Laboratorio, especialmente dirigida a Enfermería, con enlaces, bibliografía, formación...
        • 50.5.   30. Virology Down Under - un gran recurso en Virología, su información incluye enlaces y mucho más...
        • 50.6.    31. Honey Bee Viruses - Virus de las Abejas - Resumen de una tesis de PhD respecto a las interacciones de Varroa jacobsoni  y los virus de las abejas.
        • 50.7.    32. Información de Virología patrocinada por SCIENCE.ORG ª, gran información sobre virología general. Es un recurso en expansión para quién esté intersado en el estudio de virus animales.
        • 50.8.    33. Bases de Datos de Virus de la Australian National University's Bioinformatics Facility de la Escuela de Investigación de Ciencias Biológicas. En esta página puede encontrar: nomenclatura, caracterización e información sobre virus. Hay también información sobre el genoma y microfotografías de microscopio electrónico. 
          • 50.9.   34. Clasificación y nomenclatura de los virus - The Index Virum presenta listas de taxonomía viral que reflejan la clasificación aprobada por el International Committee on Taxonomy of Viruses (ICTV). El ICTV tiene ahora un mirror en el servidor de NCBI.
          • 50.10    35. Descripciones - Las descripciones son la traducción al lenguaje natural de los datos codificados almacenados en el  ICTVdB, la base de datos universal del ICTV. El código es DELTA, the DEscription Language for TAxonomy desarrollado por M. Dallwitz.
          • 50.11.   36. Viruses of Plants in Australia - Virus de las plantas en Australia. Una selección de virus descrita en el VIDEdB (Virus Idetification Data Exchange Project), desarrollada por A.J. Gibbs, usando DELTA.

          50.11.   37. Type Culture Collection - La Colección America de Cultivos Patrón (ATCC) es una entidad privada sin ánimo de lucro, dedicada a la colección, preservación y distribución de cultivos auténticos de microorganismos, virus, células animales y humanas... La organización patrocina investigaciones para asegurar la autenticidad de los materiales de su colección y para estandarizar los métodos de caracterización, mantenimiento, preservación y distribución de estos materiales.
        • 50.11.    38. Información sobre Estructura Viral y Biología en la World Wide Web
        •  50.12.     39.  CELLS alive! - Células vivas. Imágenes microscópicas de células y organismos vivos desde Quill Graphics contiene información sobre virus, parásitos y bacterias. Muy informativa.  
        • 50.13.   The "Bad Bug Book" de la U. S. Food & Drug Administration Center for Food Safety & Applied Nutrition ha puesto en la Red su listado de Microorganismos patógenos y toxinas naturales. Este manual proporciona las directrices básicas sobre el tema.
        • La verdad sobre los virus de The Health Gazette. Algunos comentarios generales sobre los virus, desde una perspectiva médica.
        • Human Virtual Virus de la página -- It's Epidemic.
        • Los Virus: La Frontera Desconocida - desarrollado por una alumno de high school  fascinado por la virología.
        • Animal Virus Information System (AVIS) está desarrollado por Bioinformatics Distributed Information Centre, Universidad de Pune, Pune, India. Describe Virus animales. Más de 1300 virus disponibles. . AVIS incluye una seccion de identificación de virus -- un método para determinar e identificar las familias de virus animales basado la implementación a de Willcox del teorema de Bayes.



          • 51.0. Recursos de Fármacos anti-Virales

            (Para información sobre fármacos anti-VIH y SIDA, ver la sección 
            Enlaces de SIDA.)



            52.0.   Inmunología Viral
            • Lymphocyte Recirculation - Recirculación de linfocitos - Un recurso de inmunología de interés para los virólogos. Recirculación de los linfocitos, la inmunofisiología que interviene. Importante debido a que muchas de estas estructuras linfáticas son diana de los virus, que evaden su detección o destruyen su efectividad.
             
             
             
             82.0. El Portal de la Virología
            La atención médica hospitalaria estándar puede ayudar a disminuir el riesgo de complicaciones en ... Enlace a otra página WEB. Presentación de MS-Powerpoint ...
            www.virologia.org/2005/west_nile.htm -
            82.1.
            82.2.
            82.3.
            82.4
            82.5
            82.6
            82.7
            82.8
            82.9
            82.10.
            82.11.
            82.12.
            82.13.
            ¿Qué virus quieres ver publicado en estas página
            83.0.PROTOCOLOS
             

            84.0. Protocolos de     ACCIDENTE BORRO TODO LO SIGUIENTE





            VIDEOS

            DR VICENTE RACANIELLO   LECTURAS 1 A 22     EDICION 2018

            YOUTUBE   VIROLOGY  RACNIELLO 2018


            YOUTUBE   VIROLOGY  RACNIELLO 2018

             

            Virology Lectures 2018       https://www.youtube.com/playlist?list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir

            Vincent Racaniello

             

             

            VER LISTA DE REPRODUCCIÓN COMPLETA (21 VIDEOS)

             

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            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

             

             

            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            https://www.youtube.com/watch?v=3olXpSqEOmY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and fundamental properties, and discuss whether or not they are alive.

             

            ttps://www.youtube.com/watch?v=3olXpSqEOmY&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22&t=0s

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

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            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

             

             

             

            3.3 K vistasHace 3 meses

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this

             

             

            https://www.youtube.com/watch?v=eYngrYhklII&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=21

             

             

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this lecture we define the infectious cycle and discuss how to study it. We cover assay of infectious virus particles by plaque assay, multiplicity of infection, and the particle to pfu ratio. We also discuss physical methods for detecting viruses including hemagglutination, polymerase chain reaction, and deep, high-throughput sequencing.

            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

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            Virology Lectures 2018 #3: Genomes and Genetics    

            Vincent Racaniello

            https://www.youtube.com/watch?v=Fcoz0RnJ364&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=20

            Viruses are unusual because their genome can be DNA or RNA, and they can occur in seven different configurations. In this lecture we review each type of viral genome and trace the pathway to mRNA. We discuss the largest and smallest genomes, what is and is not encoded in the genome, and how to manipulate the viral genome to facilitate their study and their use as vectors.

             

            https://www.youtube.com/watch?v=Fcoz0RnJ364

             

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            Virology Lectures 2018 #4: Structure of Viruses

            Vincent Racaniello

            https://www.youtube.com/watch?v=pWXzT-1gn7E&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

             

             

            Virology Lectures 2018 #4: Structure of Viruses

            2.112 visualizaciones

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            Vincent Racaniello

            Publicado el 30 ene. 2018

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            A key function of the virus particles is to protect the genome in its journey among hosts. In this lecture we describe the two major forms of symmetry for building virus particles, helical and icosahedral. We discuss how to make larger and larger viruses, the triangulation number, quasiequivalence, and metastability, and end with a discussion of the lipid envelope derived from the host cell that is embedded with viral glycoproteins.

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            https://www.youtube.com/watch?v=pWXzT-1gn7E&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

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            Virology Lectures 2018 #5: Attachment and Entry

            Virology Lectures 2018 #5: Attachment and Entry

            Vincent Racaniello

            1.9 K vistasHace 2 meses

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell

             

            2.042 visualizaciones

            Vincent Racaniello

             

            240COMPARTIR

            Vincent Racaniello

            Publicado el 1 feb. 2018

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            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell membrane. In this lecture we discuss how icosahedral and enveloped viruses attach to cell receptors, how the virus particle is destabilized, allowing the nucleic acid to enter the cell, and how membrane fusion is regulated.

             

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            Ciencia y tecnología

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            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

             

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            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

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            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

            Vincent Racaniello

             

            Vincent Racaniello

            Publicado el 10 feb. 2018

            SUSCRIBIRSE 13 MIL

             

            The genomes of RNA viruses encode RNA polymerase for replication and mRNA synthesis. In this lecture you will learn about the principles and mechanisms of RNA synthesis by RNA dependent RNA polymerases. We'll consider priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and what controls the switch from synthesis of mRNAs to genomes, in cells infected with negative strand RNA viruses, positive strand RNA viruses, and double-stranded RNA viruses.

             

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            https://www.youtube.com/watch?v=GpaCOPOfnFI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=17

             

             

             

             

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            Virology Lectures 2018 #7: Transcription and RNA Processing

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            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            https://www.youtube.com/watch?v=xDsQearF-BE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=16

             

             

            1.4 K vistasHace 2 meses

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein.

             

            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 13 feb. 2018

            SUSCRIBIRSE 13 MIL

            SUSCRIBIRSE 13 K

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein. Not all DNA viral genomes are ready for transcription and must be made into dsDNA. In this lecture, we discuss DNA dependent RNA polymerase, regulation of the process by viral proteins, positive feedback loops and transcriptional cascades, and RNA processing, the addition of 5'-cap, poly(A) tail, splicing, and RNA export.

             

             

             

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            https://www.youtube.com/watch?v=xDsQearF-BE

             

             

             

             

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            Virology Lectures 2018 #8: Viral DNA Synthesis

            Vincent Racaniello

             

            Virology Lectures 2017 #8: Viral DNA Synthesis

            Vincent Racaniello

            4.2 K vistasHace 1 año

             

            https://www.youtube.com/watch?v=zdFGRjqk_to&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=15

             

             

            DNA viruses must make at least one protein, sometimes many, for genome replication to take place. In this lecture we cover the mechanisms of DNA replication, including how viral DNA genomes recruit the host synthetic apparatus, replication by strand displacement or a replication fork, solving the 5'-end problem caused by RNA priming, how genomes of different structures are copied, and how viruses ensure that cells are actively duplicating their DNA to provide access to the DNA synthesis machinery.

             

            Every known DNA virus must make at least one protein to allow genome replication to take place. In this lecture we cover how DNA

             

             

             

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            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0r05cded9FI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=14

             

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus, and some plant viruses. In this lecture we discuss the discovery of reverse transcriptase, the mechanism of reverse transcription and integration, and its role in the cycles of retroviruses and hepatitis B virus. We also introduce retroelements, which are mobile DNA sequences that move about through the action of reverse transcriptase and constitute about 42% of the human genome.

            993 vistasHace 2 meses

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus,

             

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

            Virology Lectures 2018 #10: Assembly

            Vincent Racaniello

            971 vistasHace 2 meses

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging

            https://www.youtube.com/watch?v=YiLTCaRNboY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=13

             

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging of nucleic acids, acquisition of an envelope, and release from the infected cell.

             

             

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            Virology Lectures 2018 #11: The Infected Cell

            Vincent Racaniello

            https://www.youtube.com/watch?v=LaOaquGrydo&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=12

            Virus reproduction depend on the host cell's biosynthetic and metabolic capabilities, signal transduction pathways, and trafficking systems. In this lecture we present an integrated description of how virus infection redirects and often compromises normal cell physiology.

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

            Virology Lectures 2018 #12: Infection Basics

            Vincent Racaniello

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

            https://www.youtube.com/watch?v=JVap9YtzIrA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=11

             

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral pathogenesis the process by which viruses cause disease in their hosts. In this lecture we discuss infection basics: how viruses enter hosts, spread to different tissues, and transmit to new hosts. We also consider how geography and season may affect virus infections.

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

             

            Virology Lectures 2018 #13: Intrinsic and Innate Defenses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=mt4SeN6RTuw&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=10

             


            Vincent Racaniello

            Publicado el 13 mar. 2018

            SUSCRIBIRSE 13 K

            Many host defenses have evolved to prevent virus infections. If a virus gets past the chemical and physical defenses, next in its way stands intrinsic defenses (always present in the cell), and then innate defenses (which must be induced by infection). Both are highly effective antiviral systems, but are antagonized by many different viral proteins - one reason why viruses are successful at being maintained in populations.

             

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

             

            Virology Lectures 2018 #14: Adaptive Immunity

            Vincent Racaniello

            https://www.youtube.com/watch?v=92815jlNODE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=9


            Vincent Racaniello

            Publicado el 20 mar. 2018

            SUSCRIBIRSE 13 K

            The adaptive immune system, consisting of antibodies and T cells, is tailored to the pathogen. In this lecture we examine how the innate immune system engages the adaptive immune system, how antibodies and T cells are made, and how they prevent and resolve virus infections.

             

             

             

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            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=va2eTNKZGdE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=8

             

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how to measure it and how to identify the genes involved; various mechanisms by which the immune response causes disease; and host determinants of virus susceptibility.

             

            640 vistasHace 3 semanas

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how

             

             

             

             

             

             

             

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            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=o9xNX4J1IcI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=7


            Vincent Racaniello

            Publicado el 31 mar. 2018

            SUSCRIBIRSE 13 K

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by resolution. In this lecture we define the properties of acute infections, and illustrate them with five examples: influenza virus, poliovirus, measles virus, norovirus, and West Nile virus.

             

             

            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            565 vistasHace 3 semanas

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by

             

            59:53

             

             

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            Virology Lectures 2018 #17: Persistent Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=N-dLXrSYI2Y&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=6

            Persistent viral infections last the lifetime of the host. In this lecture we discuss the mechanisms and consequences of viral persistence, illustrated with examples of measles virus, polyomaviruses, hepatitis B and C viruses, and herpesviruse

             

             

             

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            Virology Lectures 2018 #18: Transformation and Oncogenesis

            Vincent Racaniello

            https://www.youtube.com/watch?v=BZL6Ubqy_5g&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=5

            Virus infections can lead to transformation of cells, making them immortal and placing them on the road to cancer. In this lecture we review the discovery of RNA and DNA tumor viruses and how an understanding of how they transform cells lead to an understanding of the mechanisms of cell growth control.

             

             

             

             

             

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            Virology Lectures 2018 #19: Vaccines

            Vincent Racaniello

            https://www.youtube.com/watch?v=U5Dg5-5RSuc&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=4

             

            Vaccines are a proven way to prevent viral infections. In this lecture we discuss examples of different types of vaccines, including inactivated vaccines, subunit vaccines, and replication competent, infectious vaccines. We illustrate these concepts with existing vaccines for poliovirus, influenza virus, hepatitis B virus, human papillomavirus, yellow fever virus, and dengue virus. We also consider the many experimental vaccines that are being developed for Zika virus.

             

             

             

             

             

             

             

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            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0IDoECtB0WA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=3

             

             

            381 vistasHace 1 semana

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this

             

             

            Vincent Racaniello

            Publicado el 17 abr. 2018

            SUSCRIBIRSE 13 K

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this lecture we discuss antiviral drug discovery, how some currently licensed compounds work, and the origin and mechanisms of drug resistance.

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            Ciencia y tecnología

            Licencia

            Licencia estándar de YouTube

             

             

            XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVirology Lectures 2018 #21: Evolution

            Vincent Racaniello

            ·         Virology Lectures 2018 #21: Evolution1:13:33

             

             

            https://www.youtube.com/watch?v=q7cXxcHKlvk&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=2

             

             

            191 vistasHace 3 días

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main

            Nuevo

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main drivers of viral evolution: large numbers of progeny, mutation, selection, and quasispecies effects, and discuss where viruses came from and where they are going.

             

             

            Virology Lectures 2018 #21: Evolution

            Vincent Racaniello

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            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=VfhIEwUR9e8&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=1

             

             

             

            Sin vistasHace 21 horas

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive

            Nuevo

             

             

             

             

             

             

            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 24 abr. 2018

            SUSCRIBIRSE 13 K

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive virus emergence, followed by a description of emerging virus infection including those caused by poliovirus, Nipah and Hendra viruses, Ebolavirus, SARS and MERS coronavirus and Zika virus.

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            MOSTRAR MENOS

             

             YOUTUBE   VIROLOGY  RACNIELLO 2018

             

            Virology Lectures 2018       https://www.youtube.com/playlist?list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir

            Vincent Racaniello

             

             

            VER LISTA DE REPRODUCCIÓN COMPLETA (21 VIDEOS)

             

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            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

             

             

            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            https://www.youtube.com/watch?v=3olXpSqEOmY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and fundamental properties, and discuss whether or not they are alive.

             

            ttps://www.youtube.com/watch?v=3olXpSqEOmY&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22&t=0s

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

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            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

             

             

             

            3.3 K vistasHace 3 meses

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this

             

             

            https://www.youtube.com/watch?v=eYngrYhklII&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=21

             

             

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this lecture we define the infectious cycle and discuss how to study it. We cover assay of infectious virus particles by plaque assay, multiplicity of infection, and the particle to pfu ratio. We also discuss physical methods for detecting viruses including hemagglutination, polymerase chain reaction, and deep, high-throughput sequencing.

            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

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            Virology Lectures 2018 #3: Genomes and Genetics    

            Vincent Racaniello

            https://www.youtube.com/watch?v=Fcoz0RnJ364&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=20

            Viruses are unusual because their genome can be DNA or RNA, and they can occur in seven different configurations. In this lecture we review each type of viral genome and trace the pathway to mRNA. We discuss the largest and smallest genomes, what is and is not encoded in the genome, and how to manipulate the viral genome to facilitate their study and their use as vectors.

             

            https://www.youtube.com/watch?v=Fcoz0RnJ364

             

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            Virology Lectures 2018 #4: Structure of Viruses

            Vincent Racaniello

            https://www.youtube.com/watch?v=pWXzT-1gn7E&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

             

             

            Virology Lectures 2018 #4: Structure of Viruses

            2.112 visualizaciones

            290COMPARTIR

            Vincent Racaniello

            Publicado el 30 ene. 2018

            SUSCRIBIRSE 13 MIL

            A key function of the virus particles is to protect the genome in its journey among hosts. In this lecture we describe the two major forms of symmetry for building virus particles, helical and icosahedral. We discuss how to make larger and larger viruses, the triangulation number, quasiequivalence, and metastability, and end with a discussion of the lipid envelope derived from the host cell that is embedded with viral glycoproteins.

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            Licencia de YouTube estándar

            https://www.youtube.com/watch?v=pWXzT-1gn7E&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

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            Virology Lectures 2018 #5: Attachment and Entry

            Virology Lectures 2018 #5: Attachment and Entry

            Vincent Racaniello

            1.9 K vistasHace 2 meses

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell

             

            2.042 visualizaciones

            Vincent Racaniello

             

            240COMPARTIR

            Vincent Racaniello

            Publicado el 1 feb. 2018

            SUSCRIBIRSE 13 K

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell membrane. In this lecture we discuss how icosahedral and enveloped viruses attach to cell receptors, how the virus particle is destabilized, allowing the nucleic acid to enter the cell, and how membrane fusion is regulated.

             

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            Licencia

            Licencia de YouTube estándar

            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

             

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            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

            1.794 visualizaciones

            230COMPARTIR

            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

            Vincent Racaniello

             

            Vincent Racaniello

            Publicado el 10 feb. 2018

            SUSCRIBIRSE 13 MIL

             

            The genomes of RNA viruses encode RNA polymerase for replication and mRNA synthesis. In this lecture you will learn about the principles and mechanisms of RNA synthesis by RNA dependent RNA polymerases. We'll consider priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and what controls the switch from synthesis of mRNAs to genomes, in cells infected with negative strand RNA viruses, positive strand RNA viruses, and double-stranded RNA viruses.

             

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            https://www.youtube.com/watch?v=GpaCOPOfnFI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=17

             

             

             

             

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            Virology Lectures 2018 #7: Transcription and RNA Processing

            1.521 visualizaciones

            150COMPARTIR

            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            https://www.youtube.com/watch?v=xDsQearF-BE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=16

             

             

            1.4 K vistasHace 2 meses

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein.

             

            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 13 feb. 2018

            SUSCRIBIRSE 13 MIL

            SUSCRIBIRSE 13 K

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein. Not all DNA viral genomes are ready for transcription and must be made into dsDNA. In this lecture, we discuss DNA dependent RNA polymerase, regulation of the process by viral proteins, positive feedback loops and transcriptional cascades, and RNA processing, the addition of 5'-cap, poly(A) tail, splicing, and RNA export.

             

             

             

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            https://www.youtube.com/watch?v=xDsQearF-BE

             

             

             

             

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            Virology Lectures 2018 #8: Viral DNA Synthesis

            Vincent Racaniello

             

            Virology Lectures 2017 #8: Viral DNA Synthesis

            Vincent Racaniello

            4.2 K vistasHace 1 año

             

            https://www.youtube.com/watch?v=zdFGRjqk_to&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=15

             

             

            DNA viruses must make at least one protein, sometimes many, for genome replication to take place. In this lecture we cover the mechanisms of DNA replication, including how viral DNA genomes recruit the host synthetic apparatus, replication by strand displacement or a replication fork, solving the 5'-end problem caused by RNA priming, how genomes of different structures are copied, and how viruses ensure that cells are actively duplicating their DNA to provide access to the DNA synthesis machinery.

             

            Every known DNA virus must make at least one protein to allow genome replication to take place. In this lecture we cover how DNA

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

             

            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0r05cded9FI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=14

             

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus, and some plant viruses. In this lecture we discuss the discovery of reverse transcriptase, the mechanism of reverse transcription and integration, and its role in the cycles of retroviruses and hepatitis B virus. We also introduce retroelements, which are mobile DNA sequences that move about through the action of reverse transcriptase and constitute about 42% of the human genome.

            993 vistasHace 2 meses

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus,

             

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

            Virology Lectures 2018 #10: Assembly

            Vincent Racaniello

            971 vistasHace 2 meses

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging

            https://www.youtube.com/watch?v=YiLTCaRNboY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=13

             

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging of nucleic acids, acquisition of an envelope, and release from the infected cell.

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

             

            Virology Lectures 2018 #11: The Infected Cell

            Vincent Racaniello

            https://www.youtube.com/watch?v=LaOaquGrydo&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=12

            Virus reproduction depend on the host cell's biosynthetic and metabolic capabilities, signal transduction pathways, and trafficking systems. In this lecture we present an integrated description of how virus infection redirects and often compromises normal cell physiology.

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

            Virology Lectures 2018 #12: Infection Basics

            Vincent Racaniello

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

            https://www.youtube.com/watch?v=JVap9YtzIrA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=11

             

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral pathogenesis the process by which viruses cause disease in their hosts. In this lecture we discuss infection basics: how viruses enter hosts, spread to different tissues, and transmit to new hosts. We also consider how geography and season may affect virus infections.

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

             

            Virology Lectures 2018 #13: Intrinsic and Innate Defenses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=mt4SeN6RTuw&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=10

             


            Vincent Racaniello

            Publicado el 13 mar. 2018

            SUSCRIBIRSE 13 K

            Many host defenses have evolved to prevent virus infections. If a virus gets past the chemical and physical defenses, next in its way stands intrinsic defenses (always present in the cell), and then innate defenses (which must be induced by infection). Both are highly effective antiviral systems, but are antagonized by many different viral proteins - one reason why viruses are successful at being maintained in populations.

             

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

             

            Virology Lectures 2018 #14: Adaptive Immunity

            Vincent Racaniello

            https://www.youtube.com/watch?v=92815jlNODE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=9


            Vincent Racaniello

            Publicado el 20 mar. 2018

            SUSCRIBIRSE 13 K

            The adaptive immune system, consisting of antibodies and T cells, is tailored to the pathogen. In this lecture we examine how the innate immune system engages the adaptive immune system, how antibodies and T cells are made, and how they prevent and resolve virus infections.

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=va2eTNKZGdE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=8

             

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how to measure it and how to identify the genes involved; various mechanisms by which the immune response causes disease; and host determinants of virus susceptibility.

             

            640 vistasHace 3 semanas

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how

             

             

             

             

             

             

             

            xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=o9xNX4J1IcI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=7


            Vincent Racaniello

            Publicado el 31 mar. 2018

            SUSCRIBIRSE 13 K

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by resolution. In this lecture we define the properties of acute infections, and illustrate them with five examples: influenza virus, poliovirus, measles virus, norovirus, and West Nile virus.

             

             

            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            565 vistasHace 3 semanas

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by

             

            59:53

             

             

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            Virology Lectures 2018 #17: Persistent Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=N-dLXrSYI2Y&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=6

            Persistent viral infections last the lifetime of the host. In this lecture we discuss the mechanisms and consequences of viral persistence, illustrated with examples of measles virus, polyomaviruses, hepatitis B and C viruses, and herpesviruse

             

             

             

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            Virology Lectures 2018 #18: Transformation and Oncogenesis

            Vincent Racaniello

            https://www.youtube.com/watch?v=BZL6Ubqy_5g&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=5

            Virus infections can lead to transformation of cells, making them immortal and placing them on the road to cancer. In this lecture we review the discovery of RNA and DNA tumor viruses and how an understanding of how they transform cells lead to an understanding of the mechanisms of cell growth control.

             

             

             

             

             

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            Virology Lectures 2018 #19: Vaccines

            Vincent Racaniello

            https://www.youtube.com/watch?v=U5Dg5-5RSuc&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=4

             

            Vaccines are a proven way to prevent viral infections. In this lecture we discuss examples of different types of vaccines, including inactivated vaccines, subunit vaccines, and replication competent, infectious vaccines. We illustrate these concepts with existing vaccines for poliovirus, influenza virus, hepatitis B virus, human papillomavirus, yellow fever virus, and dengue virus. We also consider the many experimental vaccines that are being developed for Zika virus.

             

             

             

             

             

             

             

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            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0IDoECtB0WA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=3

             

             

            381 vistasHace 1 semana

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this

             

             

            Vincent Racaniello

            Publicado el 17 abr. 2018

            SUSCRIBIRSE 13 K

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this lecture we discuss antiviral drug discovery, how some currently licensed compounds work, and the origin and mechanisms of drug resistance.

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            XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVirology Lectures 2018 #21: Evolution

            Vincent Racaniello

            ·         Virology Lectures 2018 #21: Evolution1:13:33

             

             

            https://www.youtube.com/watch?v=q7cXxcHKlvk&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=2

             

             

            191 vistasHace 3 días

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main

            Nuevo

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main drivers of viral evolution: large numbers of progeny, mutation, selection, and quasispecies effects, and discuss where viruses came from and where they are going.

             

             

            Virology Lectures 2018 #21: Evolution

            Vincent Racaniello

            3

             

             

             

             

             

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            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=VfhIEwUR9e8&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=1

             

             

             

            Sin vistasHace 21 horas

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive

            Nuevo

             

             

             

             

             

             

            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 24 abr. 2018

            SUSCRIBIRSE 13 K

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive virus emergence, followed by a description of emerging virus infection including those caused by poliovirus, Nipah and Hendra viruses, Ebolavirus, SARS and MERS coronavirus and Zika virus.

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            Virology Lectures 2018       https://www.youtube.com/playlist?list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir

            Vincent Racaniello

             

             

            VER LISTA DE REPRODUCCIÓN COMPLETA (21 VIDEOS)

             

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            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

             

             

            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            https://www.youtube.com/watch?v=3olXpSqEOmY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and fundamental properties, and discuss whether or not they are alive.

             

            ttps://www.youtube.com/watch?v=3olXpSqEOmY&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22&t=0s

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

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            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

             

             

             

            3.3 K vistasHace 3 meses

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this

             

             

            https://www.youtube.com/watch?v=eYngrYhklII&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=21

             

             

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this lecture we define the infectious cycle and discuss how to study it. We cover assay of infectious virus particles by plaque assay, multiplicity of infection, and the particle to pfu ratio. We also discuss physical methods for detecting viruses including hemagglutination, polymerase chain reaction, and deep, high-throughput sequencing.

            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

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            Virology Lectures 2018 #3: Genomes and Genetics    

            Vincent Racaniello

            https://www.youtube.com/watch?v=Fcoz0RnJ364&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=20

            Viruses are unusual because their genome can be DNA or RNA, and they can occur in seven different configurations. In this lecture we review each type of viral genome and trace the pathway to mRNA. We discuss the largest and smallest genomes, what is and is not encoded in the genome, and how to manipulate the viral genome to facilitate their study and their use as vectors.

             

            https://www.youtube.com/watch?v=Fcoz0RnJ364

             

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            Virology Lectures 2018 #4: Structure of Viruses

            Vincent Racaniello

            https://www.youtube.com/watch?v=pWXzT-1gn7E&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

             

             

            Virology Lectures 2018 #4: Structure of Viruses

            2.112 visualizaciones

            290COMPARTIR

            Vincent Racaniello

            Publicado el 30 ene. 2018

            SUSCRIBIRSE 13 MIL

            A key function of the virus particles is to protect the genome in its journey among hosts. In this lecture we describe the two major forms of symmetry for building virus particles, helical and icosahedral. We discuss how to make larger and larger viruses, the triangulation number, quasiequivalence, and metastability, and end with a discussion of the lipid envelope derived from the host cell that is embedded with viral glycoproteins.

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            https://www.youtube.com/watch?v=pWXzT-1gn7E&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

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            Virology Lectures 2018 #5: Attachment and Entry

            Virology Lectures 2018 #5: Attachment and Entry

            Vincent Racaniello

            1.9 K vistasHace 2 meses

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell

             

            2.042 visualizaciones

            Vincent Racaniello

             

            240COMPARTIR

            Vincent Racaniello

            Publicado el 1 feb. 2018

            SUSCRIBIRSE 13 K

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell membrane. In this lecture we discuss how icosahedral and enveloped viruses attach to cell receptors, how the virus particle is destabilized, allowing the nucleic acid to enter the cell, and how membrane fusion is regulated.

             

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            Ciencia y tecnología

            Licencia

            Licencia de YouTube estándar

            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

             

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            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

            1.794 visualizaciones

            230COMPARTIR

            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

            Vincent Racaniello

             

            Vincent Racaniello

            Publicado el 10 feb. 2018

            SUSCRIBIRSE 13 MIL

             

            The genomes of RNA viruses encode RNA polymerase for replication and mRNA synthesis. In this lecture you will learn about the principles and mechanisms of RNA synthesis by RNA dependent RNA polymerases. We'll consider priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and what controls the switch from synthesis of mRNAs to genomes, in cells infected with negative strand RNA viruses, positive strand RNA viruses, and double-stranded RNA viruses.

             

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            https://www.youtube.com/watch?v=GpaCOPOfnFI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=17

             

             

             

             

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            Virology Lectures 2018 #7: Transcription and RNA Processing

            1.521 visualizaciones

            150COMPARTIR

            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            https://www.youtube.com/watch?v=xDsQearF-BE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=16

             

             

            1.4 K vistasHace 2 meses

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein.

             

            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 13 feb. 2018

            SUSCRIBIRSE 13 MIL

            SUSCRIBIRSE 13 K

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein. Not all DNA viral genomes are ready for transcription and must be made into dsDNA. In this lecture, we discuss DNA dependent RNA polymerase, regulation of the process by viral proteins, positive feedback loops and transcriptional cascades, and RNA processing, the addition of 5'-cap, poly(A) tail, splicing, and RNA export.

             

             

             

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            https://www.youtube.com/watch?v=xDsQearF-BE

             

             

             

             

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            Virology Lectures 2018 #8: Viral DNA Synthesis

            Vincent Racaniello

             

            Virology Lectures 2017 #8: Viral DNA Synthesis

            Vincent Racaniello

            4.2 K vistasHace 1 año

             

            https://www.youtube.com/watch?v=zdFGRjqk_to&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=15

             

             

            DNA viruses must make at least one protein, sometimes many, for genome replication to take place. In this lecture we cover the mechanisms of DNA replication, including how viral DNA genomes recruit the host synthetic apparatus, replication by strand displacement or a replication fork, solving the 5'-end problem caused by RNA priming, how genomes of different structures are copied, and how viruses ensure that cells are actively duplicating their DNA to provide access to the DNA synthesis machinery.

             

            Every known DNA virus must make at least one protein to allow genome replication to take place. In this lecture we cover how DNA

             

             

             

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            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0r05cded9FI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=14

             

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus, and some plant viruses. In this lecture we discuss the discovery of reverse transcriptase, the mechanism of reverse transcription and integration, and its role in the cycles of retroviruses and hepatitis B virus. We also introduce retroelements, which are mobile DNA sequences that move about through the action of reverse transcriptase and constitute about 42% of the human genome.

            993 vistasHace 2 meses

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus,

             

             

             

             

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            Virology Lectures 2018 #10: Assembly

            Vincent Racaniello

            971 vistasHace 2 meses

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging

            https://www.youtube.com/watch?v=YiLTCaRNboY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=13

             

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging of nucleic acids, acquisition of an envelope, and release from the infected cell.

             

             

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            Virology Lectures 2018 #11: The Infected Cell

            Vincent Racaniello

            https://www.youtube.com/watch?v=LaOaquGrydo&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=12

            Virus reproduction depend on the host cell's biosynthetic and metabolic capabilities, signal transduction pathways, and trafficking systems. In this lecture we present an integrated description of how virus infection redirects and often compromises normal cell physiology.

             

             

             

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            Virology Lectures 2018 #12: Infection Basics

            Vincent Racaniello

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

            https://www.youtube.com/watch?v=JVap9YtzIrA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=11

             

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral pathogenesis the process by which viruses cause disease in their hosts. In this lecture we discuss infection basics: how viruses enter hosts, spread to different tissues, and transmit to new hosts. We also consider how geography and season may affect virus infections.

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

             

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            Virology Lectures 2018 #13: Intrinsic and Innate Defenses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=mt4SeN6RTuw&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=10

             


            Vincent Racaniello

            Publicado el 13 mar. 2018

            SUSCRIBIRSE 13 K

            Many host defenses have evolved to prevent virus infections. If a virus gets past the chemical and physical defenses, next in its way stands intrinsic defenses (always present in the cell), and then innate defenses (which must be induced by infection). Both are highly effective antiviral systems, but are antagonized by many different viral proteins - one reason why viruses are successful at being maintained in populations.

             

             

             

             

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            Virology Lectures 2018 #14: Adaptive Immunity

            Vincent Racaniello

            https://www.youtube.com/watch?v=92815jlNODE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=9


            Vincent Racaniello

            Publicado el 20 mar. 2018

            SUSCRIBIRSE 13 K

            The adaptive immune system, consisting of antibodies and T cells, is tailored to the pathogen. In this lecture we examine how the innate immune system engages the adaptive immune system, how antibodies and T cells are made, and how they prevent and resolve virus infections.

             

             

             

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            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=va2eTNKZGdE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=8

             

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how to measure it and how to identify the genes involved; various mechanisms by which the immune response causes disease; and host determinants of virus susceptibility.

             

            640 vistasHace 3 semanas

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how

             

             

             

             

             

             

             

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            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=o9xNX4J1IcI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=7


            Vincent Racaniello

            Publicado el 31 mar. 2018

            SUSCRIBIRSE 13 K

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by resolution. In this lecture we define the properties of acute infections, and illustrate them with five examples: influenza virus, poliovirus, measles virus, norovirus, and West Nile virus.

             

             

            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            565 vistasHace 3 semanas

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by

             

            59:53

             

             

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            Virology Lectures 2018 #17: Persistent Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=N-dLXrSYI2Y&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=6

            Persistent viral infections last the lifetime of the host. In this lecture we discuss the mechanisms and consequences of viral persistence, illustrated with examples of measles virus, polyomaviruses, hepatitis B and C viruses, and herpesviruse

             

             

             

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            Virology Lectures 2018 #18: Transformation and Oncogenesis

            Vincent Racaniello

            https://www.youtube.com/watch?v=BZL6Ubqy_5g&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=5

            Virus infections can lead to transformation of cells, making them immortal and placing them on the road to cancer. In this lecture we review the discovery of RNA and DNA tumor viruses and how an understanding of how they transform cells lead to an understanding of the mechanisms of cell growth control.

             

             

             

             

             

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            Virology Lectures 2018 #19: Vaccines

            Vincent Racaniello

            https://www.youtube.com/watch?v=U5Dg5-5RSuc&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=4

             

            Vaccines are a proven way to prevent viral infections. In this lecture we discuss examples of different types of vaccines, including inactivated vaccines, subunit vaccines, and replication competent, infectious vaccines. We illustrate these concepts with existing vaccines for poliovirus, influenza virus, hepatitis B virus, human papillomavirus, yellow fever virus, and dengue virus. We also consider the many experimental vaccines that are being developed for Zika virus.

             

             

             

             

             

             

             

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            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0IDoECtB0WA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=3

             

             

            381 vistasHace 1 semana

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this

             

             

            Vincent Racaniello

            Publicado el 17 abr. 2018

            SUSCRIBIRSE 13 K

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this lecture we discuss antiviral drug discovery, how some currently licensed compounds work, and the origin and mechanisms of drug resistance.

            Categoría

            Ciencia y tecnología

            Licencia

            Licencia estándar de YouTube

             

             

            XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVirology Lectures 2018 #21: Evolution

            Vincent Racaniello

            ·         Virology Lectures 2018 #21: Evolution1:13:33

             

             

            https://www.youtube.com/watch?v=q7cXxcHKlvk&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=2

             

             

            191 vistasHace 3 días

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main

            Nuevo

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main drivers of viral evolution: large numbers of progeny, mutation, selection, and quasispecies effects, and discuss where viruses came from and where they are going.

             

             

            Virology Lectures 2018 #21: Evolution

            Vincent Racaniello

            3

             

             

             

             

             

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            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=VfhIEwUR9e8&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=1

             

             

             

            Sin vistasHace 21 horas

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive

            Nuevo

             

             

             

             

             

             

            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 24 abr. 2018

            SUSCRIBIRSE 13 K

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive virus emergence, followed by a description of emerging virus infection including those caused by poliovirus, Nipah and Hendra viruses, Ebolavirus, SARS and MERS coronavirus and Zika virus.

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            MOSTRAR MENOS

             YOUTUBE   VIROLOGY  RACNIELLO 2018

             

            Virology Lectures 2018       https://www.youtube.com/playlist?list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir

            Vincent Racaniello

             

             

            VER LISTA DE REPRODUCCIÓN COMPLETA (21 VIDEOS)

             

            XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

             

             

            Virology Lectures 2018 #1: What is a Virus?

            Vincent Racaniello

            https://www.youtube.com/watch?v=3olXpSqEOmY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and fundamental properties, and discuss whether or not they are alive.

             

            ttps://www.youtube.com/watch?v=3olXpSqEOmY&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=22&t=0s

            5.5 K vistasHace 3 meses

            In this first lecture of my 2018 Columbia University virology course, we explore the definitions of viruses, their discovery and

            XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

             

            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

             

             

             

            3.3 K vistasHace 3 meses

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this

             

             

            https://www.youtube.com/watch?v=eYngrYhklII&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=21

             

             

            The infectious cycle is the entire sequence of events from virus binding to cells to release of new progeny virus particles. In this lecture we define the infectious cycle and discuss how to study it. We cover assay of infectious virus particles by plaque assay, multiplicity of infection, and the particle to pfu ratio. We also discuss physical methods for detecting viruses including hemagglutination, polymerase chain reaction, and deep, high-throughput sequencing.

            Virology 2018 Lecture #2: The Infectious Cycle

            Vincent Racaniello

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            Virology Lectures 2018 #3: Genomes and Genetics    

            Vincent Racaniello

            https://www.youtube.com/watch?v=Fcoz0RnJ364&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=20

            Viruses are unusual because their genome can be DNA or RNA, and they can occur in seven different configurations. In this lecture we review each type of viral genome and trace the pathway to mRNA. We discuss the largest and smallest genomes, what is and is not encoded in the genome, and how to manipulate the viral genome to facilitate their study and their use as vectors.

             

            https://www.youtube.com/watch?v=Fcoz0RnJ364

             

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            Virology Lectures 2018 #4: Structure of Viruses

            Vincent Racaniello

            https://www.youtube.com/watch?v=pWXzT-1gn7E&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

             

             

            Virology Lectures 2018 #4: Structure of Viruses

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            Vincent Racaniello

            Publicado el 30 ene. 2018

            SUSCRIBIRSE 13 MIL

            A key function of the virus particles is to protect the genome in its journey among hosts. In this lecture we describe the two major forms of symmetry for building virus particles, helical and icosahedral. We discuss how to make larger and larger viruses, the triangulation number, quasiequivalence, and metastability, and end with a discussion of the lipid envelope derived from the host cell that is embedded with viral glycoproteins.

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            https://www.youtube.com/watch?v=pWXzT-1gn7E&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=19

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            Virology Lectures 2018 #5: Attachment and Entry

            Virology Lectures 2018 #5: Attachment and Entry

            Vincent Racaniello

            1.9 K vistasHace 2 meses

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell

             

            2.042 visualizaciones

            Vincent Racaniello

             

            240COMPARTIR

            Vincent Racaniello

            Publicado el 1 feb. 2018

            SUSCRIBIRSE 13 K

            Viruses are obligate intracellular parasites and must enter cells to replicate, but they are too big to simply pass through the cell membrane. In this lecture we discuss how icosahedral and enveloped viruses attach to cell receptors, how the virus particle is destabilized, allowing the nucleic acid to enter the cell, and how membrane fusion is regulated.

             

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            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

            https://www.youtube.com/watch?v=lVpMhL8dtqE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=18

             

             

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            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

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            Virology Lectures 2018 #6: RNA Directed RNA Synthesis

            Vincent Racaniello

             

            Vincent Racaniello

            Publicado el 10 feb. 2018

            SUSCRIBIRSE 13 MIL

             

            The genomes of RNA viruses encode RNA polymerase for replication and mRNA synthesis. In this lecture you will learn about the principles and mechanisms of RNA synthesis by RNA dependent RNA polymerases. We'll consider priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and what controls the switch from synthesis of mRNAs to genomes, in cells infected with negative strand RNA viruses, positive strand RNA viruses, and double-stranded RNA viruses.

             

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            https://www.youtube.com/watch?v=GpaCOPOfnFI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=17

             

             

             

             

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            Virology Lectures 2018 #7: Transcription and RNA Processing

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            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            https://www.youtube.com/watch?v=xDsQearF-BE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=16

             

             

            1.4 K vistasHace 2 meses

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein.

             

            Virology Lectures 2018 #7: Transcription and RNA Processing

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 13 feb. 2018

            SUSCRIBIRSE 13 MIL

            SUSCRIBIRSE 13 K

            The first step in cells infected with double-stranded DNA viruses is transcription, the synthesis of mRNAs for translation into protein. Not all DNA viral genomes are ready for transcription and must be made into dsDNA. In this lecture, we discuss DNA dependent RNA polymerase, regulation of the process by viral proteins, positive feedback loops and transcriptional cascades, and RNA processing, the addition of 5'-cap, poly(A) tail, splicing, and RNA export.

             

             

             

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            https://www.youtube.com/watch?v=xDsQearF-BE

             

             

             

             

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            Virology Lectures 2018 #8: Viral DNA Synthesis

            Vincent Racaniello

             

            Virology Lectures 2017 #8: Viral DNA Synthesis

            Vincent Racaniello

            4.2 K vistasHace 1 año

             

            https://www.youtube.com/watch?v=zdFGRjqk_to&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=15

             

             

            DNA viruses must make at least one protein, sometimes many, for genome replication to take place. In this lecture we cover the mechanisms of DNA replication, including how viral DNA genomes recruit the host synthetic apparatus, replication by strand displacement or a replication fork, solving the 5'-end problem caused by RNA priming, how genomes of different structures are copied, and how viruses ensure that cells are actively duplicating their DNA to provide access to the DNA synthesis machinery.

             

            Every known DNA virus must make at least one protein to allow genome replication to take place. In this lecture we cover how DNA

             

             

             

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            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

            Virology Lectures 2018 #9: Reverse Transcription and Integration

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0r05cded9FI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=14

             

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus, and some plant viruses. In this lecture we discuss the discovery of reverse transcriptase, the mechanism of reverse transcription and integration, and its role in the cycles of retroviruses and hepatitis B virus. We also introduce retroelements, which are mobile DNA sequences that move about through the action of reverse transcriptase and constitute about 42% of the human genome.

            993 vistasHace 2 meses

            Reverse transcriptase, an enzyme that produces DNA from RNA, is central to the reproduction cycle of retroviruses, hepatitis B virus,

             

             

             

             

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            Virology Lectures 2018 #10: Assembly

            Vincent Racaniello

            971 vistasHace 2 meses

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging

            https://www.youtube.com/watch?v=YiLTCaRNboY&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=13

             

            In this lecture we discuss how virus particles are assembled. We cover sequential or concerted assembly line processes, packaging of nucleic acids, acquisition of an envelope, and release from the infected cell.

             

             

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            Virology Lectures 2018 #11: The Infected Cell

            Vincent Racaniello

            https://www.youtube.com/watch?v=LaOaquGrydo&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=12

            Virus reproduction depend on the host cell's biosynthetic and metabolic capabilities, signal transduction pathways, and trafficking systems. In this lecture we present an integrated description of how virus infection redirects and often compromises normal cell physiology.

             

             

             

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            Virology Lectures 2018 #12: Infection Basics

            Vincent Racaniello

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

            https://www.youtube.com/watch?v=JVap9YtzIrA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=11

             

            1 K vistasHace 1 mes

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral pathogenesis the process by which viruses cause disease in their hosts. In this lecture we discuss infection basics: how viruses enter hosts, spread to different tissues, and transmit to new hosts. We also consider how geography and season may affect virus infections.

            At this point in this lecture series we move from studying virus infection in cell culture to animal hosts, and to understand viral

             

             

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            Virology Lectures 2018 #13: Intrinsic and Innate Defenses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=mt4SeN6RTuw&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=10

             


            Vincent Racaniello

            Publicado el 13 mar. 2018

            SUSCRIBIRSE 13 K

            Many host defenses have evolved to prevent virus infections. If a virus gets past the chemical and physical defenses, next in its way stands intrinsic defenses (always present in the cell), and then innate defenses (which must be induced by infection). Both are highly effective antiviral systems, but are antagonized by many different viral proteins - one reason why viruses are successful at being maintained in populations.

             

             

             

             

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            Virology Lectures 2018 #14: Adaptive Immunity

            Vincent Racaniello

            https://www.youtube.com/watch?v=92815jlNODE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=9


            Vincent Racaniello

            Publicado el 20 mar. 2018

            SUSCRIBIRSE 13 K

            The adaptive immune system, consisting of antibodies and T cells, is tailored to the pathogen. In this lecture we examine how the innate immune system engages the adaptive immune system, how antibodies and T cells are made, and how they prevent and resolve virus infections.

             

             

             

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            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

            Virology Lectures 2018 #15: Mechanisms of Pathogenesis

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=va2eTNKZGdE&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=8

             

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how to measure it and how to identify the genes involved; various mechanisms by which the immune response causes disease; and host determinants of virus susceptibility.

             

            640 vistasHace 3 semanas

            Viral pathogenesis, the development of disease, has both viral and host determinants. In this lecture we discuss viral virulence, how

             

             

             

             

             

             

             

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            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=o9xNX4J1IcI&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=7


            Vincent Racaniello

            Publicado el 31 mar. 2018

            SUSCRIBIRSE 13 K

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by resolution. In this lecture we define the properties of acute infections, and illustrate them with five examples: influenza virus, poliovirus, measles virus, norovirus, and West Nile virus.

             

             

            Virology Lectures 2018 #16: Acute Infections

            Vincent Racaniello

            565 vistasHace 3 semanas

            Virus infections are acute or persistent. An acute infection is finite: rapid onset of virus reproduction, course of disease followed by

             

            59:53

             

             

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            Virology Lectures 2018 #17: Persistent Infections

            Vincent Racaniello

            https://www.youtube.com/watch?v=N-dLXrSYI2Y&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=6

            Persistent viral infections last the lifetime of the host. In this lecture we discuss the mechanisms and consequences of viral persistence, illustrated with examples of measles virus, polyomaviruses, hepatitis B and C viruses, and herpesviruse

             

             

             

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            Virology Lectures 2018 #18: Transformation and Oncogenesis

            Vincent Racaniello

            https://www.youtube.com/watch?v=BZL6Ubqy_5g&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=5

            Virus infections can lead to transformation of cells, making them immortal and placing them on the road to cancer. In this lecture we review the discovery of RNA and DNA tumor viruses and how an understanding of how they transform cells lead to an understanding of the mechanisms of cell growth control.

             

             

             

             

             

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            Virology Lectures 2018 #19: Vaccines

            Vincent Racaniello

            https://www.youtube.com/watch?v=U5Dg5-5RSuc&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=4

             

            Vaccines are a proven way to prevent viral infections. In this lecture we discuss examples of different types of vaccines, including inactivated vaccines, subunit vaccines, and replication competent, infectious vaccines. We illustrate these concepts with existing vaccines for poliovirus, influenza virus, hepatitis B virus, human papillomavirus, yellow fever virus, and dengue virus. We also consider the many experimental vaccines that are being developed for Zika virus.

             

             

             

             

             

             

             

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            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

            Virology Lectures 2018 #20: Antivirals

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=0IDoECtB0WA&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=3

             

             

            381 vistasHace 1 semana

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this

             

             

            Vincent Racaniello

            Publicado el 17 abr. 2018

            SUSCRIBIRSE 13 K

            If no viral vaccines are available, or if an infection has taken place in a non-vaccinated individual, antiviral drugs may be used. In this lecture we discuss antiviral drug discovery, how some currently licensed compounds work, and the origin and mechanisms of drug resistance.

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            Ciencia y tecnología

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            XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVirology Lectures 2018 #21: Evolution

            Vincent Racaniello

            ·         Virology Lectures 2018 #21: Evolution1:13:33

             

             

            https://www.youtube.com/watch?v=q7cXxcHKlvk&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=2

             

             

            191 vistasHace 3 días

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main

            Nuevo

            Viral evolution is the constant change of a viral population in the face of selection pressures. In this lecture we consider the four main drivers of viral evolution: large numbers of progeny, mutation, selection, and quasispecies effects, and discuss where viruses came from and where they are going.

             

             

            Virology Lectures 2018 #21: Evolution

            Vincent Racaniello

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            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

             

            https://www.youtube.com/watch?v=VfhIEwUR9e8&t=0s&list=PLGhmZX2NKiNmB3DbuYHDLDv8Ft313tQir&index=1

             

             

             

            Sin vistasHace 21 horas

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive

            Nuevo

             

             

             

             

             

             

            Virology Lectures 2018 #22: Emerging Viruses

            Vincent Racaniello

            Vincent Racaniello

            Publicado el 24 abr. 2018

            SUSCRIBIRSE 13 K

            Emerging viruses are causative agents of new or previously unrecognized infections. In this lecture we discuss the factors that drive virus emergence, followed by a description of emerging virus infection including those caused by poliovirus, Nipah and Hendra viruses, Ebolavirus, SARS and MERS coronavirus and Zika virus.

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            86. STEPHEN HARRISON, U. Harvard

            Estructura Viral

            Parte 1 https://www.youtube.com/watch?v=KoJWuWzVgqQ

            PARTE II  https://www.youtube.com/watch?v=qcepGvFUM38

            PARTE III  https://www.youtube.com/watch?v=-1tSBwE1Wuk


            87. Coursera

            VIROLOGÍA

            https://es.coursera.org/course/virology

            https://es.coursera.org/course/virology2


            ÉBOLA

            https://www.coursera.org/learn/ebola-vaincre-ensemble

            https://www.coursera.org/learn/ebola-essentials-for-health-professionals


            LAS VACUNAS

            https://es.coursera.org/course/vaccines


            BACTERIAS

            https://es.coursera.org/course/bacteria


            RESOLUCIÓN DE PROBLEMAS CLÍNICOS

            https://es.coursera.org/course/clinprobsolv


            TUBERCULOSIS

            https://es.coursera.org/course/tbmanagement


            SIDA

            https://es.coursera.org/course/aids


            88.   CURSOS EDX

            INMUNOLOGÍA

            https://www.edx.org/course/fundamentals-immunology-part-2-ricex-bioc372-2x


            HIV

            https://www.edx.org/course/representations-hivaids-davidsonx-d002


            89. KHAN ACADEMY

            ENFERMEDADES INFECCIOSAS

            https://es.khanacademy.org/science/health-and-medicine/infectious-diseases


            90. http://webdelmaestrocmf.com/portal/

              

            91. http://webdelmaestrocmf.com/portal/docentes-3-maneras-

            de-hacer-tus-clases-mas-innovadoras/


            92. http://webdelmaestrocmf.com/portal/5-herramientas-crear-examenes-docentes/


            93   AMBOSS  https://www.amboss.com/us     Resúmenes de ciencias médicas básicas, microbiologia, virología, bacteriología, parasitologia, micologia, cuestionarios, casos clínicos, revisiones por aparatos y sistemas, historias clínicas, casos clínicos, imagenes. Materiales para el USML , para preparar especialidades medicas.  Muy utilizada por estudiantes alemanes y americanos. Abra su cuenta , haga un aporte económico y reciba los beneficios.

            94.UP TO DATE       

            UpToDate  https://itunes.apple.com/us/app/uptodate/id334265345?mt=8

            From Wikipedia, the free encyclopedia
            Jump to navigationJump to search

            UpToDate, Inc. is a company in the Wolters Kluwer Health division of Wolters Kluwer whose main product is UpToDate, a software system that is a point-of-care medical resource.

            The UpToDate system is marketed as an evidence-based clinical resource. It includes a collection of medical and patient information, access to Lexi-comp drug monographs and drug-to-drug, drug-to-herb and herb-to-herb interactions information, and a number of medical calculators. UpToDate is written by over 5,700 physician authors, editors and peer reviewers. It is available both via the Internet and offline on personal computers or mobile devices. It requires a subscription for full access.

            The company was launched in 1992 by Dr. Burton D. Rose along with Dr. Joseph Rush out of Rose's home.[1] They started with nephrology and have since added over twenty other specialties, with more in development.

            UpToDate's articles are anonymously peer reviewed and it mandates the disclosure of conflicts of interest by the authors of its articles. In 2014 an article was published in the Journal of Medical Ethics which scrutinised six articles on UpToDate and DynaMed focusing on conditions where the best means of management is contested, or which are treated mostly by branded drugs. The authors found that all six articles examined from UpToDate contained numerous potential conflicts of interest, with contributors having worked as consultants for or received research grants or speaking fees from manufacturers of drugs mentioned in the relevant UpToDate entry.[2]

            Access[edit]

            Full access to the service requires a subscription, which cost US$495 per year as of 2014.[3] UpToDate was made available for free in New Zealand after the Christchurch earthquake, in Haiti in 2010 and in Nepal in 2015 after the earthquake.[4] The Global Health Delivery Project at Harvard University administers access to UpToDate for those who offer medical care to poor or underserved populations outside the United States.[5]

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