Lab. of Molecular Neurobiology and BioPhysics
Mechanisms of ion channels and membrane proteins in neuro-glia-vascular physiology
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Every cell is enclosed by a thin, highly selective membrane that serves as both a protective barrier and a dynamic interface with the extracellular environment. Membrane proteins embedded in this boundary are essential for cellular life, controlling the movement of ions and solutes and generating the electrical signals that underlie nervous system function.
Our laboratory investigates membrane proteins in the nervous system, with a focus on ion channels and transporters. By integrating electrophysiology, membrane protein biochemistry, cell biology, and cryo-electron microscopy, we seek to define their structures, elucidate their mechanisms, and understand their roles in physiology and disease.
Recent events
Recent events
GI2RC Signboard Unveiling Ceremony
('26.10.15, KBRI)
Global Ion Channel Innovation Research Center (GI2RC) Opening Ceremony
('26.10.12, DGIST)
Visit of NIPS Director General Tadashi Isa to KBRI
('26.10.12, KBRI)
2025 SGP meeting
('25.9.3~7, Woods Hole, MA)
2025 KSBNS, CJK Neuroscience
('25.8.24~27, Songdo)
International Ion Channel Conference ('25.7.14~18., Guiyang, China)
Functional characterization of PIP2-dependent PAC channel activation at the single channel level was published in "Nature Communications" (Euna and Hyun-Ho; as co-authors) in collaboration with Prof. Suh, BC at the DGIST.
Structural and functional studies on mouse Best1 channel was recently published in "Mol. Cells" (Kun-Woo, Euna, and Ara; as co-first authors).
A study on the development of a synthetic ion channel by using G-quadruple in collaboration with Prof. Oh, Seung-soo at the POSTECH was recently published in "Advanced Materials"(Kunwoong and Hyun-Ho*, *co-corresponding author).
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