THE PAYUMO LAB
Cardiac Regenerative Biology
Cultured cardiomyocytes, sarcomeres labeled in red, nuclei in blue; Cover art by Alex Payumo.
Welcome to the Payumo Lab!
Welcome to the Payumo Lab!
We are located at San Jose State University in Duncan Hall Room 445. Our lab aims to provide a comprehensive training environment for SJSU undergraduate and graduate students interested in conducting scientific research.
We are located at San Jose State University in Duncan Hall Room 445. Our lab aims to provide a comprehensive training environment for SJSU undergraduate and graduate students interested in conducting scientific research.
Our research program focuses on understanding the molecular and cellular mechanisms limiting the proliferative capacity of cardiomyocytes, specialized cells responsible for heart contractility. After a heart attack, cardiomyocytes die and are permanently lost resulting in pathological cardiac remodeling, heart disease, and human death. By understanding cardiomyocyte cell-cycle regulation, our lab hopes to identify new therapeutic targets that may guide strategies in cardiac regenerative medicine to better treat ischemic injury and protect against heart disease.
Our research program focuses on understanding the molecular and cellular mechanisms limiting the proliferative capacity of cardiomyocytes, specialized cells responsible for heart contractility. After a heart attack, cardiomyocytes die and are permanently lost resulting in pathological cardiac remodeling, heart disease, and human death. By understanding cardiomyocyte cell-cycle regulation, our lab hopes to identify new therapeutic targets that may guide strategies in cardiac regenerative medicine to better treat ischemic injury and protect against heart disease.
Neonatal rat cardiomyocytes spontaneously contracting in culture. Video by Alex Payumo.