Hyun-Lim Yang (양현림), Ph.D.
Research Assistant Professor / Dept. of Anesthesiology and Pain Medicine,
Deputy Head / Division of Medical Device Evaluation and Licensing,
@ Seoul National University Hospital
Ph.D. in Computer Science (Artificial Intelligence)
hlyang@snu.ac.kr ; hly@snuh.org
[Google Scholar] [ORCID]
I am a Research Assistant Professor at Biomedical Research Institute and a Research Fellow member of VitalLab at Dept. of Anesthesiology and Pain Medicine of Seoul National University Hospital (SNUH). I am also a deputy head of a Division of medical device evaluation and licensing of SNUH. I currently conducting research on analyzing vital signal from real world medical practice and developing medical AI systems. I am interested in AI transformation of clinical decision support systems.
I obtained Ph.D. in Computer Science (major in Artificial Intelligence) at the Daegu Gyeongbuk Institute of Science and Technology (DGIST) where I was greatly fortunate to be advised by Min-Soo Kim (currently at KAIST) and co-advised by Daehoon Kim. Before that, I obtained M.S. and B.S. in Industrial Engineering at the Kyonggi University where I was blessed to be advised by Tai-Woo Chang.
Latest News
[2024.01] Our AI-based SaMD, APCONet, has been approved as a software medical device by the Ministry of Food and Drug Safety of Korea! (품목인증번호: 제인 24-113호)
[2024.01] A new co-authored paper was accepted to EClinicalMedicine (SCIE, IF=15.1, JCR top 8.28%). "Deep learning-based long-term risk evaluation of incident type 2 diabetes using electrocardiogram in a non-diabetic population: a retrospective, multicentre study"
[2023.11] A new co-authored paper was accepted to npj Digital Medicine (SCIE, IF=15.2, JCR top 0.94%, rank #1). "Real-time machine learning model to predict in-hospital cardiac arrest using heart rate variability in ICU"
Publications
# : co-first / ⁎ : corresponding
[J15] J. Kim, H.-L. Yang, S.-H. Kim, S. Kim, J. Lee, J. Ryu, K. Kim, Z. Kim, G. Ahn, D. Kwon, H.-J. Yoon, "Deep learning-based long-term risk evaluation of incident type 2 diabetes using electrocardiogram in a non-diabetic population: a retrospective, multicentre study", EClinicalMedicine, 2024 (SCIE, IF=15.1, JCR top 8.28%), https://doi.org/10.1016/j.eclinm.2024.102445
[J14] D. Yun, H.-L. Yang, S.K. Kwon, S.-R. Lee, K. Kim, K. Kim, H.-C. Lee, C.-W. Jung, Y.S. Kim, S.S. Han*, "Automatic segmentation of atrial fibrillation and flutter in single-lead electrocardiograms by self-supervised learning and Transformer architecture", Journal of the American Medical Informatics Association, 2024. (SCIE, IF=6.4, JCR top 9.43%), https://doi.org/10.1093/jamia/ocad219
[J13] H. Lee, H.-L. Yang, H.G. Ryu, C.-W. Jung, Y.J. Cho, S.B. Yoon, H.-K. Yoon, H.-C. Lee*, "Real-time machine learning model to predict in-hospital cardiac arrest using heart rate variability in ICU", npj Digital Medicine, 2023. (SCIE, IF=15.2, JCR top 0.94%, #1), https://doi.org/10.1038/s41746-023-00960-2
[J12] D. Yun, H.-L. Yang, S.G. Kim, K. Kim, D.K. Kim, K.-H. Oh, K.W. Joo, Y.S. Kim, S.S. Han*, "Real-time dual prediction of intradialytic hypotension and hypertension using an explainable deep learning model", Scientific Report, 2023. (SCIE, IF=4.6), https://doi.org/10.1038/s41598-023-45282-1
[J11] J.-B. Park, H.-J. Lee, H.-L. Yang, E.-H. Kim, H.-C. Lee, C.-W. Jung, H.-S. Kim*, "Machine learning-based prediction of intraoperative hypoxemia for pediatric patients", PLoS One, 2023. (SCIE, IF=3.752), https://doi.org/10.1371/journal.pone.0282303
[J10] H.-Y. Cho#, K. Lee#, H.-J. Kong, H.-L. Yang, C.-W. Jung, H.-P. Park, J.-Y. Hwang, H.-C. Lee*, "Deep-learning model associating lateral cervical radiographic features with Cormack–Lehane grade 3 or 4 glottic view", Anaesthesia, 2022 (SCIE, IF=12.893, JCR top 1.47%, #1), https://doi.org/10.1111/anae.15874
[C4] S.-A Park, H.-C. Lee, C.-W. Jung, H.-L. Yang*, "Attention mechanisms for physiological signal deep learning: which attention should we take?", MICCAI 2022 (top conference in medical AI area). (acceptance rate=31%), http://arxiv.org/abs/2207.06904, https://doi.org/10.1007/978-3-031-16431-6_58
[J9] H.-K. Yoon, H.-L. Yang, C.-W. Jung, H.-C. Lee*, "Artificial intelligence in perioperative medicine: a narrative review", Korean Journal of Anesthesiology, 2022 (SCIE, IF=5.167), https://doi.org/10.4097/kja.22157
[J8] H.-L. Yang, C.-W Jung, S.-M. Yang, M.-S. Kim, S. Shim, K.-H. Lee, H.-C. Lee*, "Development and validation of an arterial pressure-based cardiac output algorithm using a convolutional neural network: Retrospective study based on prospective registry data", JMIR Medical Informatics, 2021 (SCIE, IF=3.231) ;9(8):e24762, https://doi.org/10.2196/24762
[J7] J.G. Nam#, J.W. Kim#, K. Noh, H. Chio, D.S. Kim, S.-J. Yoo, H.-L. Yang, E.J. Hwang, J.M. Goo, E.-A. Park, H.Y. Sun, M.-S. Kim*, C.M. Park*, "Automatic Prediction of Left Cardiac Chamber Enlargement from Chest Radiographs using Convolutional Neural Network", European Radiology, 2021. (SCIE, IF=7.034, JCR top 15%), https://doi.org/10.1007/s00330-021-07963-1
[C3] H.-L. Yang, H.-C. Lee, C.-W. Jung, M.-S. Kim*, "A Deep Learning Method for Intraoperative Age-agnostic and Disease-specific Cardiac Output Monitoring from Arterial Blood Pressure" (Full paper track), IEEE International conference on bioinformatics and bioengineering (IEEE BIBE) 2020, https://doi.org/10.1109/BIBE50027.2020.00112
[J6] H.-L. Yang, J.J. Kim, J.H. Kim, Y.K. Kang, D.H. Park, H.S. Park, H.K. Kim*, M.-S. Kim*, "Weakly supervised lesion localization for age-related macular degeneration detection using optical coherence tomography images", PLOS ONE, 2019. (SCIE, IF=2.766) https://doi.org/10.1371/journal.pone.0215076
[C2] 양현림, 이형철, 김민수, 정철우, "딥러닝 기반의 동맥압파형에서 심박출량을 추정하는 알고리즘 - VitalDB를 이용하여", 대한의료정보학회 추계학술대회 심포지엄, 2019
[J5] H.-L. Yang, T.W. Chang* and Y. Choi, "Exploring the Research Trend of Smart Factory with Topic Modeling", Sustainability, 10(8), 2018. (SCIE, SSCI, IF=2.592) https://doi.org/10.3390/su10082779
[J4] T.W. Chang* and H.-L. Yang, "Latent Semantic Analysis of Research Papers on Smart Factory", ICIC Express Letters, 11(4), 2017.
[C1] 양현림, 장태우, "텍스트마이닝을 이용한 스마트팩토리 관련 연구동향 분석", 한국스마트미디어학회&한국전자거래학회 공동추계학술대회, 2016.
[J3] H.L. Yang, H.Y. Oh, H.J. Lee, T.W. Chang*, "A Study on Mobile Service through Analysis of Business Model Patents", Journal of the Korea Management Engineers Society, 21(4), 2016.
[J2] H.L. Yang and T.W. Chang*, "Development of Multiple Visual Devices for 3D Surveillance of Big Structure", ICIC Express Letters Part B: Applications, 7(9), 2016.
[J1] H.L. Yang and T.W. Chang*, "An R-based Genetic Algorithm for Placement of Surveillance Cameras", ICIC Express Letters, 10(6), 2016.
[P3] 김희수, 정철우, 이형철, 양현림, "소아환자용 일회박출량 인덱스 추정 시스템 및 방법" (KR: 10-2447962)
[P2] 정철우, 이형철, 양현림, 김민수, "AI를 이용한 일회박출량 산출 장치 및 방법" (KR; PCT: 10-2377609)
[P1] 장태우, 문준영, 양현림, 임준형, 정지운, "감시장비 배치장치 및 방법" (KR: 10-1711521)
[D1] APCONet, 제인 24-113호, 생체신호 분석 소프트웨어 E052020.01(2), 대한민국 식품의약품안전처
Related Works: "Development and validation of an arterial pressure-based cardiac output algorithm using a convolutional neural network: Retrospective study based on prospective registry data", JMIR Medical Informatics, 2021;9(8):e24762, https://doi.org/10.2196/24762
Related Patents: "AI를 이용한 일회박출량 산출 장치 및 방법" (KR; PCT: 10-2377609)
Press Article: https://www.etoday.co.kr/news/view/2340154
https://www.dailymedi.com/news/news_view.php?wr_id=909531
[Ph.D. Thesis] "Exploiting the Intermediate Layers of Convolutional Neural Networks for Medical Deep Learning", DGIST, 2021.02
[M.S. Thesis] "A Study on Research Trends of Smart Factory using Keyword Analysis and Topic Modeling", Graduate School in Kyonggi University, 2017.02
Research Projects
[On-going]
암흑데이터 극한활용 연구센터 (주관: 대구경북과학기술원)
참여연구원, 선도연구센터사업, 한국연구재단 (NRF)
인공지능기반 예측지표 활용 가능한 원격지원형 융복합 환자감시장치 개발 (주관: 서울대학교병원)
참여연구원, 범부처전주기의료기기연구개발사업, KMDF
한국형 중환자 특화 빅데이터 (K-MIMIC) 구축 및 AI-CDSS 개발 IMPACT 컨소시엄 (주관: 서울대학교병원)
참여연구원, 중환자 특화 빅데이터 구축 및 AI기반 CDSS 개발 컨소시엄, 보건복지부
ECG와 PPG 기반 딥러닝 모델을 이용한 실시간 비침습적 심박출량 예측 시스템 개발
연구책임자, 의생명연구원 일반연구과제, 서울대학교병원, 2023-2024
[Past]
환자감시장치의 클라우드 연결을 통한 지능형 의료사물인터넷 플랫폼 구축 (주관: 서울대학교)
참여연구원, 범부처전주기의료기기연구개발사업, KMDF
딥러닝 기반의 수술 중 최소침습형 심박출량 예측 알고리즘에 대한 전향적 관찰 연구
연구책임자, 혁신의료기술 연구과제, 서울대학교병원, 2021-2022
Academic Experiences
Lecturer @ K-MOOC (with KOHI)
Course: 의료 인공지능 개론
Topic: 의료인공지능기술 2: 생체신호 데이터 분석 기법 (RNN, Transformer)
Lecturer (Team teaching) @ 서울대학교 의과대학
Date: Nov. 7, 2023
Course: 의료와 데이터사이언스 (의예과 전공선택)
Topic: 인공지능을 활용한 데이터 분석
Lecturer (Team teaching) @ 서울대학교 의과대학 대학원
Date: Nov. 1, 2023
Course: 의생명 빅데이터를 활용한 인공지능의 이해와 실습
Topic: 병원 생체신호 빅데이터 수집 및 활용
Lecturer (Team teaching) @ 서울대학교 의과대학 대학원
Date: Oct. 25, 2023
Course: Data Science in Perioperative Medicine
Topic: Machine Learning - Tree-based models
Lecturer @ 전북대학교 컴퓨터공학부 전공심화교육
Date: Nov. 19, 2022 ~ Dec. 4, 2022
Course: 의료 데이터 분석 교육
Topic: 의료 영상 기초, 의료영상 분석 및 실습, EMR/생체신호 기초, EMR/생체신호 분석 및 실습
Team mentor @ KOHI (한국보건복지인력개발원)
Date: Sep. 2022 ~ Nov. 2022
Course: 의료 인공지능 전문가 양성과정 (2022) 팀프로젝트
Lecturer @ 대한마취약리학회 2022 Vital Recorder Workshop
Date: Sep. 17, 2022
Course: 생체신호 이용 연구사례
Lecturer @ KOHI (한국보건복지인력개발원)
Date: Aug. 13, 2022 / Sep. 3, 2022
Course: 의료 인공지능 전문가 양성과정 (2021)
Topic: 생체신호 데이터 전처리 및 분석 실습 / 인공지능을 활용한 생체신호 데이터 분석 실습
Lecturer @ 서울대학교 의과대학 대학원
Date: May. 12, 2022
Course: 의료데이터사이언스의 이해와 실습
Topic: 생체신호 분석 실습
Team mentor @ KOHI (한국보건복지인력개발원)
Date: Oct. , 2021 ~ Dec. 2021
Course: 의료 인공지능 전문가 양성과정 (2021) 팀프로젝트
Lecturer (Team teaching) @ 서울대학교 융합과학기술대학원 헬스케어융합학과
Date: Oct. 19, 2021
Course: 생체신호 분석을 위한 기계학습
Topic: 수술장 생체신호 데이터의 임상적 해석과 분석 (실습)
Lecturer @ KOHI (한국보건복지인력개발원)
Date: Jul. 31, 2021 / Sep. 4, 2021
Course: 의료 인공지능 전문가 양성과정 (2021)
Topic: 인공지능을 이용한 생체신호 분석 사례 / 인공지능을 활용한 생체신호 데이터 분석 실습
Lecturer @ KoSAIM 2021 춘계학술대회
Date: May. 21, 2021
Course: Hands-on session 2: Medical Signal
Topic: 생체 신호 분석의 실제 (2) 심전도
Visiting Ph.D Student @ Seoul National University Hospital (SNUH)
Period: 2018.09 ~ 2021.01
Collaborate with:
Dept. of Anesthesiology and Pain Medicine, Seoul National University Hospital
Devision of Clinical Bioinformatics, Biomedical Research Institute, Seoul National University Hospital
Dept. of Radiology, Seoul National University Hospital
Lecturer @ KOHI (한국보건복지인력개발원)
Date: Oct. 24, 2020 / Oct. 26, 2019
Course: 의료 인공지능 전문가 양성과정 (2020, 2019)
Topic: ML models for waveform analysis
Lecturer @ KoSAIM 2020 Summer School (대한의료인공지능학회 여름학교)
Date: Aug. 22, 2020
Course: Hands-on session 2: Medical Signal
Topic: CNN
Awards and Honors
The 2023 Excellence In Technology Award @STA 2023 Best Abstract Awards
Society for Technology in Anesthesia (STA) 2023, Las Vegas, Nevada. (12, Jan., 2023)
Presenter: Seong-A Park, Corresponding Author: Hyun-Lim Yang.
"A Non-invasive Algorithm for Predicting Cardiac Output Using a Convolutional Neural Network"
First Runner Up Awards (rank 3 among selected 21 teams) @ Singapore Healthcare AI Datathon & Expo (SHADE) 2022
Singapore Healthcare AI Datathon & Expo (SHADE) 2022, National University Singapore (NUS) and National University Health System (NUHS)
"Development of an AI model for non-invasive prediction of cardiac output"
3rd Prize @ MAIC Challenge
SNUH Medical AI Challenge, Seoul National University Hospital
"CDM AI challenge: Forecasting AKI"
Second Runner Up Awards (rank 4 among 57 teams) @ Singapore Healthcare AI Datathon 2021
Singapore Healthcare AI Datathon & Expo 2021, National University Singapore (NUS) and National University Health System (NUHS)
"AI model for Intraoperative Hypoxemia Prediction"
Full government scholarship (Ph.D. program)
The Best Research Awards (Abstract competition) @ KoreAnesthesia 2020
The 97th Annual Scientific Meeting of the Korean Society of Anesthesiologist (대한마취통증의학회 국제학술대회), [11/2020]
"Development of an uncalibrated arterial pressure-based cardiac output algorithm on using a convolutional neural network and transfer learning technique"
제 5회 산업융합 활성화 방안 및 사례연구 논문공모전 장려(한국생산기술연구원장상)
국가산업융합지원센터 / 대한산업공학회 [11/2016]
한국 SCM학회 대학생 경진대회 동상
한국 SCM학회 [06/2015]
"수출컨테이너 적입량 증대방안"
Invited Talks and Seminar
Invited talk @ 대한전자공학회 2022 추계학술대회
Date: Nov. 25, 2022
Topic: Attention mechanisms for physiological signal deep learning: which attention should we take? (MICCAI 2022 presented)
Seminar @ Chungnam National University Biomedical Research Institute
Date: Jun. 16, 2022
Topic: 병원 생체신호 빅데이터의 수집 및 활용 사례 - 중환자실과 수술실을 중심으로
Special talk @ Kyonggi University (산업인공지능 전문인력 양성사업 특강)
Date: Apr. 12, 2022
Topic: 의료 인공지능 데이터 분석 사례
News and Updates
[2024.01] Our AI-based SaMD, APCONet, has been approved as a software medical device by the Ministry of Food and Drug Safety of Korea! (품목인증번호: 제인 24-113호)
[2024.01] A new co-authored paper was accepted to EClinicalMedicine (SCIE, IF=15.1, JCR top 8.28%). "Deep learning-based long-term risk evaluation of incident type 2 diabetes using electrocardiogram in a non-diabetic population: a retrospective, multicentre study"
[2023.11] A new co-authored paper was accepted to npj Digital Medicine (SCIE, IF=15.2, JCR top 0.94%, rank #1). "Real-time machine learning model to predict in-hospital cardiac arrest using heart rate variability in ICU"
[2023.11] A new co-authored paper was accepted to Journal of the American Medical Informatics Associations (SCIE, IF=6.4, JCR top 9.43%). "Automatic segmentation of atrial fibrillation and flutter in single-lead electrocardiograms by self-supervised learning and Transformer architecture"
[2023.10] A new co-authored paper was accepted to Scientific Report (SCIE, IF=4.6). "Real-time dual prediction of intradialytic hypotension and hypertension using an explainable deep learning model"
[2023.03] Our team member (Seong-A Park) won the 2023 Excellence In Technology Award at Society for Technology in Anesthesia (STA) 2023! "A Non-invasive Algorithm for Predicting Cardiac Output Using a Convolutional Neural Network"
[2023.02] A new co-authored paper was accepted to PLoSOne (SCIE, IF=3.752). "Machine learning-based prediction of intraoperative hypoxemia for pediatric patients"
[2022.12] Our team won the First Runner Up Awards (top 3 among selected 21 teams) at Singapore Healthcare AI Datathon & Expo (SHADE) 2022! "Development of an AI model for non-invasive prediction of cardiac output"
[2022.10] A new co-authored paper was accepted to Anaesthesia (SCIE, IF=12.893, JCR top 1.47%, #1). "A deep learning model for predicting a difficult laryngoscopy based on a cervical spine lateral X-ray image"
[2022.06] A new paper was accepted to MICCAI 2022 (top conference in medical AI area). "Attention mechanisms for physiological signal deep learning: which attention should we take?"
[2022.05] A new co-authored review paper was accepted to Korean Journal of Anesthesiology (SCIE, IF=5.167). "Artificial intelligence in perioperative medicine: a narrative review"
[2021.12] Our team won the 3rd Prize (rank 4 among 57 teams) at MAIC challenge! "CDM AI challenge: Forecasting AKI"
[2021.12] Our team won the Second Runner Up Awards (top 6 among 62 teams) at Singapore Healthcare AI Datathon 2021! "AI model for Intraoperative Hypoxemia Prediction"
[2021.09] I've been appointed as a deputy head of a Division of medical regulatory affairs, Seoul National University Hospital.
[2021.08] A new paper was accepted to JMIR Medical Informatics (SCIE, IF=3.231). "Development and validation of an arterial pressure-based cardiac output algorithm using a convolutional neural network: Retrospective study based on prospective registry data"
[2021.03] A new co-authored paper was accepted to European Radiology (SCIE, IF=7.034, JCR top 15%). "Automatic Prediction of Left Cardiac Chamber Enlargement from Chest Radiographs using Convolutional Neural Network"
[2021.02] I've started works at Seoul National University Hospital as Research Assistant Professor.
[2021.02] I graduated from the DGIST!
[2020/11] Our team won the best research award for abstract competition at KoreAnesthesia 2020. "Development of an uncalibrated arterial pressure-based cardiac output algorithm on using a convolutional neural network and transfer learning technique"
[2020/10] A new paper was presented to IEEE BIBE2020. "A Deep Learning Method for Intraoperative Age-agnostic and Disease-specific Cardiac Output Monitoring from Arterial Blood Pressure"
[2019/04] A new paper was accepted to PLOS ONE (SCIE, IF=2.766). "Weakly supervised lesion localization for age-related macular degeneration detection using optical coherence tomography images"
[2018/09] I've started doing projects at Seoul National University Hospital as Visiting PhD Student.
[2018/08] A new paper was accepted to Sustainability (SCIE, IF=2.592). "Exploring the Research Trend of Smart Factory with Topic Modeling"
[2017/03] I've joined InfoLab. at DGIST as a PhD student.