International Journal Papers
2012.
This paper presents a cost-effective, rapid, and fully automated lab-on-a-disc for simultaneous detection of multiple protein biomarkers in raw samples such as whole blood or whole saliva.
Single suspended carbon nanowires (CNWs) integrated on carbon-MEMS (CMEMS) structures are fabricated by electrospinning of SU-8 photoresist followed by pyrolysis.
[29]
Tanmoy Maitra, Swati Sharma, Alok Srivastava, Yoon-Kyoung Cho, Marc Madou, Ashutosh Sharma* , "Improved graphitization and electrical conductivity of suspended carbon nanofibers derived from carbon nanotube/polyacrylonitrile composites by directed electrospinning", Carbon, Volume 50, Issue 5, April 2012, Pages 1753–1761
Single suspended carbon nanofibers on carbon micro-structures were fabricated by direct electrospinning and subsequent pyrolysis at 900 °C of carbon nanotube/polyacrylonitrile (CNT/PAN) composite material.
2011.
[28] Hyundoo Hwang, Seung-Hoon Kim, Tae-Hyeong Kim, Je-Kyun Park, and Yoon-Kyoung Cho*, "Paper on a disc: Balancing the capillary-driven flow with a centrifugal force",
Lab Chip, 2011, 11, 3404-3406 , Top 10 the most accessed articles in Aug. and in Sep. 2011. This paper describes the active control of the capillary-driven flow in paper using a centrifugal device.
[27] Hyundoo Hwang, Dongsik Han, Young-Jae Oh, Yoon-Kyoung Cho, Ki-Hun Jeong, Je-Kyun Park*, "In situ dynamic measurements of the enhanced SERS signal using an optoelectrofluidic SERS platform," Lab Chip, 2011, 11, 2518-2525 Top 10 the most accessed articles in June. 2011.
In situ measurements of the enhanced SERS signal are demonstrated by using dynamic SERS active sites resulted from optically induced electrokinetic mechanisms.
we present a novel pumping technique for the centrifugal microfluidic disc platform, termed the thermo-pneumatic pump (TPP), that enables fluids to be transferred the center of a rotating disc by the thermal expansion of air.
[25] Hyundoo Hwang, Hak-Hyun Kim, and Yoon-Kyoung Cho*, "Elastomeric membrane valves in a disc", Lab Chip, 2011,11 (8), 1434 - 1436, Communication (IF=6.478) Top 10 the most accessed articles in Mar. 2011.

We present elastomeric membrane valves integrated into a centrifugal microfluidic platform for precise control of fluid on a disc.
[24] Rattikan Chantiwas, Sunggook Park*, Steven A. Soper*, Byoung Choul Kim, Shuichi Takayama*, Vijaya Sunkara, Hyundoo Hwang and Yoon-Kyoung Cho*,”Flexible Fabrication and Applications of Polymer Nanochannels and Nanoslits”, Chem. Soc. Rev. 2011 (IF=20.09) 40,
3677-3702, Critical Review.

The fabrication of nanochannels in thermoplastics and elastomers is critically reviewed along with their potential applications.
[23] Vijaya Sunkara, Dong-Kyu Park, Hyundoo Hwang, Rattikan Chantiwas, Steven A Soper and Yoon-Kyoung Cho*, “Simple Room Temperature Bonding of Thermoplastics and Poly(dimethylsiloxane)“ Lab Chip, 2011, 11, 962-965 (IF=6.478), The most accessed articles in Dec. 2010. and Feb. 2011.

We report a simple, versatile, instantaneous and irreversible method for bonding thermoplastics to elastomeric polydimethylsiloxane (PDMS) at room temperature.
[22] Beom Seok Lee, Yang Ui Lee, Han-Sang Kim, Tae-Hyeong Kim, Jiwoon Park, Jeong-Gun Lee, Jintae Kim, Hanshin Kim, Wee Gyo Lee, and Yoon-Kyoung Cho*, “Fully integrated lab-on-a-disc for simultaneous analysis of biochemistry and immunoassay from whole blood”, Lab Chip, 2011, 11, 70-78
We report a fully integrated lab-on-a-disc system for simultaneous analysis of clinical chemistry and enzyme-linked immuno-sorbent assay (ELISA) from whole blood.
2010.
[21] Rattikan Chantiwas, Mateusz L. Hupert, Swathi R. Pullagurla, Subramanian Balamurugan, Jesús Tamarit López, Sunggook Park, Proyag Datta, Jost Goettert, Yoon-Kyoung Cho, and Steven A. Soper*, “Simple replication methods for producing 1D nanoslits in thermoplastics and the transport dynamics of double-stranded DNA through these slits“, Lab Chip, 2010, 10, 3255-3264 (IF=6.478)
Distinct elastic interface of surface microfluidics enables novel three-dimensional (deformable) and time-dependent (capacitive) operations of the surface flow.
We report the on-chip concentration of bacteria using a dielectrophoretic (DEP) chip with 3D electrodes and subsequent laser-based DNA extraction in the same chip.
[19] Robert Gorkin, Jiwoon Park, Jonathan Siegrist, Mary Amasia, Beom Seok Lee, Jong-Myeon Park, Jintae Kim, Hanshin Kim, Marc Madou and Yoon-Kyoung Cho*, "Centrifugal Microfluidics for Biomedical Applications" Lab Chip, 1758-1773, 2010 (IF=6.478) top 10 accessed on the web in July 2010
This paper presents an in-depth review of the centrifugal microfluidic platform for biomedical applications, while highlighting recent progress in the field and outlining the potential for future applications.
Microfabrication technologies have a high potential for novel approaches to access living cells at a cellular or even at a molecular level.
We report an insulator-based (or, electrodeless) dielectrophoresis utilizing microfabricated plastic membranes.
[16] Beom Seok Lee, Jung-Nam Lee, Jong-Myeon Park, Jeong-Gun Lee, Suhyeon Kim, Yoon-Kyoung Cho* and Christopher Ko, “A fully automated immunoassay from whole blood on a disc”, Lab Chip, 2009, 9, 1548-1555 top 10 accessed on the web in May 2009 (IF=6.478)
We report a disc-based and fully automated microfluidic enzyme-linked immuno-sorbent assay (ELISA) system for the quantification of proteins from whole blood.
2000 ~ 2008 @ Samsung
[15] Yoon-Kyoung Cho, Jeong-Gun Lee, Young-Sun Lee, Jong-Myeon Park, Beom-Seok Lee, Christopher Ko, “One-step Pathogen Specific DN A Extraction from Whole Blood on a Centrifugal Microfluidic Device”, Lab Chip, 7, 565-573, 2007. (IF=6.478), Selected as the front cover story.
We report a fully integrated, pathogen-specific DNA extraction CD platform utilizing innovative laser irradiated ferrowax microvalves (LIFM) and the rapid cell lysis method using target separation and laser-irradiated magnetic bead system (TS-LIMBS).
[14] Jong-Myeon Park+, Yoon-Kyoung Cho+, Beom-Seok Lee, Jeong-Gun Lee, Christopher Ko, "Multifunctional Microvalves Control by Optical illumination on Nanoheaters and its Application in Centrifugal Microfluidic Devices", Lab Chip, 7, 557-564, 2007. (IF=6.478)

We report a novel phase change based microvalve for rapid and versatile operation of multiple microvalves using nanoheaters, 10 nm-sized iron oxide nanoparticles dispersed in paraffin wax, and laser irradiation.
[13] Sangmin Shin, Inseok Kang, Yoon-Kyoung Cho*, “A new method to measure zeta potentials of microfabricated channels by applying a time-periodic electric field in a T channel”, Colloids and Surfaces A: Physicochem. Eng. Aspects, 294, 228-235, 2006. (IF=1.926)
[12] Daesung Yoon, Yoon-Kyoung Cho*, Kwangwook Oh*, Sunhee Kim, Youngah Kim, Jungim Han, Geunbae Lim, “A Microfluidic Gel Valve Device Using Reversible Sol-gel Transition of Methyl Cellulose for Biomedical Application”, Microsystem Technologies, 12, 238-246, 2006 (IF=1.229)
[11] Yoon-Kyoung Cho, Jintae Kim, Youngsun Lee, Young-A Kim, Kak Namkoong, Heekyun Lim,a Kwang W. Oh, Suhyeon Kim, Jungim Han, Chinsung Park, Y. Eugene Pak, Christopher Ko, Chang-Seok Ki, Jong Rak Choi and Hyeon-Koon Myeong, “Clinical evaluation of micro-scale chip-based PCR system for rapid detection of hepatitis B virus”, Biosensors and Bioelectronics, 21, 2161-2169, 2006. (IF=5.143), Selected as ScienceDirect TOP25 Hottest Articles
[10] Kwang W. Oh,* Chinsung Park, Kak Namkoong, Jintae Kim, Kyeong-Sik Ock, Suhyeon Kim, Young-A Kim, Yoon-Kyoung Cho and Christopher Ko, “World-to-chip microfluidic interface with built-in valves for multichamber chip-based PCR assays”, Lab Chip, 8, 845-850, 2005. (IF=6.478), Selected for inclusion in the RSC’s Chemical Biology Virtual Journal* (Issue 12, 2005)
[9] Sangmin Shin, Inseok Kang, Yoon-Kyoung Cho, “Mixing Enhancement by using electrokinetic instability under time-periodic electric field”, J. Micromech. Microeng. 15(3), 455-462, 2005. (IF=2.233)
[8] Yoon-Kyoung Cho, Sunhee Kim, Young A Kim, Hee Kyun Lim, Kyusang Lee, DaeSung Yoon, Geunbae Lim, Y. Eugene Pak, Tai Hwan Ha and Kwan Kim, “Characterization of DNA immobilization and subsequent hybridization using in situ quartz crystal microbalance, fluorescence spectroscopy, and surface plasmon resonance”, Journal of Colloid Interface and Science, 278, 44-52, 2004. (IF=2.443) Selected as ScienceDirect TOP25 Hottest Articles
1994 ~ 1999 @ UUIUC, USA (Ph.D)
[7] Yoon-Kyoung Cho and Steve Granick, “A surface forces platform for dielectric measurements”, J. Chemical Physics, 119,1,547-554, 2003 (IF= 3.149)
[6] Yoon-Kyoung Cho, Sunhee Kim, Geunbae Lim and Steve Granick, “A Surface Forces Study of DNA Hybridization”, Langmuir, 17, 7732-7734, 2001 (IF= 4.097)
[5] Yoon-Kyoung Cho, Hiroshi Watanabe and Steve Granick, “Dielectric Response of Polymer Films Confined between Mica Surfaces”, J. Chem. Phys, 110, 9688-9696, 1999. (IF= 3.149)
[4] Yoon-Kyoung Cho, Ali Dhinojwala, and Steve Granick, “Apparent Hydrodynamic Thickness of Densely Grafted Polymer Layers in a Theta Solvent”, J. of Polymer Science: Part B: Polymer Physics, 35, 2961-2968, 1997. (IF= 1.586)
[3] Yoon-Kyoung Cho, Lenore Cai, and Steve Granick, “Molecular Tribology of Lubricants and Additives”, Tribology Intl., 30, 12, 889-894, 1997. (IF= 1.423)
[2] Yoon-Kyoung Cho and Steve Granick, “Shear of Confined Perfluorinated Molecules: Effect of Side Branching”, Wear, 200, 346-352, 1996. (IF= 1.509) Invited Paper for the Celebration of 200th Edition
1992 ~ 1994 @ POSTECH, Korea (MS)
[1] Yoon-Kyoung Cho, Kunwoo Han, and Kun-Hong Lee, “Separation of CO2 by Modified -Al2O3 Membranes at high temperature”, J. Membrane Science, 104, 3, 219-230, 1995. (IF= 3.247)
Books and Book Chapters
Yoon-Kyoung Cho, Hiroshi Watanabe and Steve Granick, “Dielectric Response of Ultrathin Confined Polymers”, Polymer Surfaces (World Scientific), Ed. by A. Karim, P. 229, 2000
Domestic Journal Papers
[4] Daesung Yoon, Kwangwook Oh, Junhoe Cha, Yoon-Kyoung Cho, Geun-bae Lim, “Microactuators in BioMEMS”, ICASE MAGAZINE, 8, 1, 22-31, 2002.
[3] Geun-bae Lim, Yoon-Kyoung Cho, “ Lab-on-a-chip for DNA analysis”, Journal of the Korean Society of Precision Engineering, 17, 11, 25-35, 2000. Bio-technology special invited paper
[2] Sang-yup Lee, Sungho Yoon, Geun-bae Lim, Yoon-Kyoung Cho, “Genomics와 DNA chip” News & Information for Chemical Engineers (NICE), 18, 3, 307–311, 2000. special invited paper
[1] Kun-Hong Lee, Yoon-Kyoung Cho, Kunwoo Han, “Separation of CO2 by Modified g-Al2O3 Membranes”, Journal of the Korean Institute of Chemical Engineers, 33, 5, 570-579, 1995.
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