Emily A. Wiley  W.M. Keck Science Center 925 N. Mills Ave. Claremont, CA 91711 (909) 607-9698 Email: ewiley@ksd.claremont.edu Education 1996 Ph.D., University of Washington, Molecular Genetics, Dept. of Pathology 1989 B.S. Biology (magna cum laude), Western Washington University Academic Positions 2008-present Associate Professor, Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges 2002-2008 Assistant Professor, Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges 2000-2002 Visiting Assistant Professor, Biology, Mount Holyoke College 1999-2000 Postdoctoral Fellow with Dr. Meng-Chao Yao, Fred Hutchinson Cancer Res. Cntr. 1996-1999 Postdoctoral Fellow with Dr. David Allis, University of Rochester1991-1996 Graduate Student with Dr. Virginia Zakian, Fred Hutchinson Cancer Research Center, and Princeton University 1989-1991 Lab Technician I in the Div. of Infectious Disease, Children's Hospital, Seattle, WAHonors, Awards, Fellowships 2006-present NSF CAREER Award 2009 American Publishers PROSE Award for book (co-editor): “Current Protocols Essential Laboratory Techniques" Wiley and Sons, Inc., New Jersey 2005, 2008 Pitzer Faculty Research Award 2003 Mellon Faculty Enhancement Award 1998 Fellowship Award, New College Teachers Workshop, SVHE 1997-2000 NIH Postdoctoral Fellowship Award Publications (*indicates student authors)
Slade, KM., *Freggiaro, S., *Cottrell, K.A., Smith, J.J., and Wiley, E.A. (2011) Sirtuin-mediated nuclear differentiation and programmed degradation in Tetrahymena. BMC Cell Biology 12(1):40-54. Coyne, R.S., Thiagarajan, M., Jones, K.M., Wortman, J.R., Tallon, L.J., Haas, B.J., Cassidy-Hanley, D.M., Wiley, E.A., et al. (2008) Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure. BMC Genomics 9: 562-579. Smith, J., *Torigoe, S., *Maxson, J., *Fish, L., and Wiley, E.A. (2008) A class II HDAC deacetylates newly-synthesized histones in Tetrahymena. Eukaryotic Cell 7(3): 471-482. Gallagher, S.R. and Wiley, E.A., Editors. (2008) Current Protocols: Essential Laboratory Techniques, Wiley and Sons, Inc., New Jersey. (Winner, 2009 PROSE award for Excellence in Biological Education) Wiley, E. A. and Chakravarti, D. (2008) “Measurement of pH” in Current Protocols: Essential Laboratory Techniques, Wiley and Sons, Inc., New Jersey.*Parker, K., *Maxson, J., *Mooney, A., and Wiley, E.A. (2007) Class I histone deacetylase Thd1p promotes global chromatin condensation in Tetrahymena thermophila. Eukaryotic Cell 6: 1913-1924. Wiley, E.A., *Myers, T., *Parker, K., *Braun, T., Yao, M.-C. (2005) The class I histone deacetylase Thd1p affects nuclear integrity in Tetrahymena thermophila. Eukaryotic Cell 4: 981-990. Wiley, E.A., Ohba, R., Yao, M.-C., Allis, C.D. (2000) Developmentally regulated Rpd3p homolog specific to the transcriptionally active macronucleus of vegetative Tetrahymena thermophila. Mol. Cell. Biol. 20(22):8319-8328. Wiley, E.A., Mizzen, C., Allis, C.D. (2000) Isolation and characterization of in vivo modified histones and an activity gel assay for identification of histone acetyltransferases. Methods in Cell Biology: Tetrahymena thermophila. Academic Press, San Diego, CA., Vol. 62:379 - 394. Huang, H., Smothers, J.F., Wiley, E.A., Allis, C.D. (1999) A nonessential HP1-like protein affects starvation-induced assembly of condensed chromatin and gene expression in macronuclei of Tetrahymena thermophila. Mol. Cell. Biol. 19(5):3624-3634.Huang, H., Wiley, E.A., Lending, C.R., Allis, C.D. (1998) An HP1-like protein is missing from transcriptionally silent micronuclei of Tetrahymena. Proc. Natl. Acad. Sci. USA 95: 13624-13629. Wiley, E.A. and Zakian, V.A. (1995) Extra telomeres, but not internal tracts of telomeric DNA, reduce transcriptional repression at Saccharomyces telomeres. Genetics 139:67-79. Mendelman, P.M., Chaffin D.O., Kilov, L.R., Kalaitzoglou, G., Serfass, D.A., Onay, O., Wiley, E.A., Overturf, G.D., Rubin, L.G. (1990) Cefuroxime treatment failure of nontypable Haemophilus influenzae meningitis associated with alteration of penicillin-binding proteins. Journal of Infectious Disease 162:1118-1123.Mendelman, P.M., Wiley E.A., Stull, T.L., Clausen, C., Chaffin, D.O., Onay, O. (1990) Problems with current recommendations for susceptibility testing of Haemophilus influenza. Antimicrobial Agents and Chemotherapy 34(8):1480 – 1484. Mendelman, P.M., Henritzy, L.L., Chaffin, D.O., Lent, K., Smith, A.L., Stull, T.L., Wiley, E.A. (1989) In vitro activities and targets of three cephem antibiotics against Haemophilus influenzae. Antimicrobial Agents and Chemotherapy 33(11):1878 – 1882.
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