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Publications

  • Jelcic I, Hsu KC, Kakalacheva K, Breiden P, Dupont B, Uhrberg M, Martin R, Münz C, and Lünemann JD. Killer immunoglobulin-like receptor locus polymorphisms in multiple sclerosis. J. Multiple Sclerosis in press.
  • Schönberg K, Hejazi M, Uhrberg M. Clonal analysis of NK cell effector functions by multi-parameter flow cytometry. Methods Mol Biol, In press.
  • Bienemann K, Iouannidou K, Schönberg K, Reuther S, Feyen O, Huck K,  Schuster F, Uhrberg M, Laws H-J, and Borkhardt  A (2011). iNKT cell reference values in healthy children and adolescents. Scand J Immunol 74:406-11. 
  • Schönberg K, Fischer JC, Kögler G, and Uhrberg M (2011). Neonatal NK cell repertoires are functionally but not structurally biased towards recognition of self HLA class I. Blood. 2011 Mar 17. [Epub ahead of print] 
  • Santourlidis S, Wernet P, Springer J, Kriegs C, Neves R, Zhao X, Zaehres H, Graffmann N, Ghanjati F, Kögler G, and Uhrberg M (2011). Uncommitted epigenetic signatures of embryonic stem cell pluripotency genes in unrestricted somatic stem cells (USSC) from human umbilical cord blood. Stem Cell Res. 6:60-69. 
  • Schönberg K, Sribar M, Enczmann J, Fischer JC, and Uhrberg M (2011). Analyses of HLA-C-specific KIR repertoires in donors with group A and B haplotypes suggest a ligand-instructed model of NK cell receptor aquisition. Blood, 117:98-107.
  • Correia MP, Costa AV, Uhrberg M, Cardoso EM, and Arosa FA (2010). IL-15 induces CD8+ T cells to acquire functional NK receptors capable of modulating cytotoxicity and cytokine secretion. Immunobiology. 2010 Sep 24. [Epub ahead of print]
  • Neves R, Scheel C, Weinhold S, Honisch E, Iwaniuk KM, Trompeter H-I, Niederacher D, Wernet P, Santourlidis S, and Uhrberg M (2010). Role of DNA methylation in miR-200c/141cluster silencing in invasive breast cancer cells. BMC Res Notes. 2010 Aug 3;3:219. 
  • Zaehres H, Kögler G, Arauzo-Bravo MJ, Bleidissel M, Santourlidis S, Weinhold S, Greber B, Kim JB, Buchheiser A, Liedtke S, Eilken HM, Graffmann N, Zhao X, Meyer J, Reinhardt P, Burr B, Waclawczyk S, Ortmeier C, Uhrberg M, Schöler HR, Cantz T, and Wernet P (2010). Induction of pluripotency in human cord blood unrestricted somatic stem cells. Exp Hematol. 38:809-18
  • Rathmann S, Glatzel S, Schönberg K, Uhrberg M, Follo M, Schulz-Huotari C, Kaymer M, Veelken H, Finke J, and Fisch P (2010). Expansion of NKG2A(-)LIR1(-) NK cells in HLA-matched, KIR/HLA-ligand mismatched patients following hematopoietic cell transplantation. Biol Blood Marrow Transplant, 16:469-81.
  • Correia, MP, Cardoso EM, Pereira CF, Neves R, Uhrberg M, and Arosa FA (2009). Hepatocytes and IL-15: a favorable microenvironment for T cell survival and CD8+ T cell differentiation. J Immunol, 182:6149-59.
  • Hasenkamp J, Borgerding A, Uhrberg M, Falk C, Chapuy B, Wulf G, Jung W, Trümper L, and Glass B (2008). Self-tolerance of human natural killer cells lacking self-HLA-specific inhibitory receptors. Scand J Immunol, 67:218-29.
  • Schönberg K, Trompeter H-I, and Uhrberg M (2008). Delivery of DNA into natural killer cells for immunotherapy. Methods Mol Biol 423:165-172.
  • Santourlidis S, Graffmann N, Christ J, and Uhrberg M (2008). Lineage-specific transition of histone signatures in the KIR locus from hematopoietic progenitor to natural killer cells. J Immunol, 80:418-25.
  • Gomez-Lozano N, Trompeter HI, de Pablo R, Estefania E, Uhrberg M, and Vilches C.  (2007) Epigenetic silencing of potentially functional KIR2DL5 alleles: Implications for the acquisition of KIR repertoires by NK cells. Eur J Immunol, 37:1954-65.
  • Grinstein E, Du Y, Santourlidis S, Christ J, Uhrberg M, and Wernet P (2007). Nucleolin regulating gene expression in CD34 positive hematopoietic cells. J Biol Chem, 82:12439-49.
  • Fischer JC, Ottinger H, Ferencik S, Beelen DW, Schwan MA, Wernet P, Grosse-Wilde H, and Uhrberg M (2007). Relevance of C1 and C2 Epitopes for Hemopoietic Stem Cell Transplantation: Role for Sequential Acquisition of HLA-C-Specific Inhibitory Killer Ig-Like Receptor. J Immunol, 178:3918-23.
  • Uhrberg M, Schönberg K, Weinhold S, and Trompeter H-I (2006). Non-viral gene delivery into primary natural killer lymphocytes. FASEB J, 20:2660.
  • Hasenkamp J, Borgerding A, Wulf G, Uhrberg M, Jung W, Dingeldein S, Truemper L, and Glass B (2006). Resistance against natural killer cell cytotoxicity: analysis of mechanisms. Scand J Immunol, 64:444-449.
  • Graffmann N, Santourlidis S, Christ J, Wernet P, and Uhrberg M (2006). Direct and quantitative analysis of chromatin accessibility by MIRECAL- A Micrococcus nuclease/ Real-time PCR chromatin accessibility assay with locus specificity. Anal Biochem, 354:308-310.
  • Trundley AE, Hiby SE, Chang C, Sharkey AM, Santourlidis S, Uhrberg M, Trowsdale J, and Moffett A (2006). Molecular characterization of KIR3DL3. Immunogenetics 57:904-916.
  • Uhrberg M (2005). The CD107 mobilization assay: viable isolation and immunotherapeutic potential of tumor-cytolytic NK cells. Leukemia 19:707-709.
  • Trompeter H-I, Gomez-Lozano N, Santourlidis S, Eisermann B, Wernet P, Vilches C, and Uhrberg M. (2005). Three Structurally and Functionally Divergent Kinds of Promoters Regulate Expression of Clonally Distributed Killer Ig-Related Receptor (KIR), of KIR2DL4, and of KIR3DL3 Expression of KIR genes in NK cells.  J Immunol 174:4135-4143.
  • Uhrberg M (2005).  Commentary: The KIR gene family: Life in the fast lane of evolution. Eur J Immunol 35:10-15.
  • Uhrberg M (2005). Shaping the human NK cell repertoire: An epigenetic glance at KIR gene regulation. Mol Immunol 42:471-475.
  • Becker S, Tonn T, Füssel T, Uhrberg M, Bogdanow M, Seifried E, and Seidl C (2003). Assessment of Killer Cell Immunoglobulin-like receptor (KIR) expression and corresponding HLA-class I phenotypes demonstrates heterogeneous KIR expression independent of anticipated HLA-class I ligands. Human Immunol, 183-193.
  • Trompeter H-I, Weinhold S, Thiel C, Wernet P, and Uhrberg M (2003). Rapid and efficient gene transfer into natural killer cells by nucleofection. J Immunol Methods, 274:245-256.
  • Santourlidis S, Trompeter H-I, Weinhold S, Eisermann B, Meyer KL, Wernet P, and Uhrberg M (2002). Crucial role of DNA methylation in determination of clonally distributed KIR expression patterns in natural killer cells. J Immunol 169:4253-4261.
  • Uhrberg M, Parham P, and Wernet P (2002). Definition of gene content for nine common group B haplotypes of the caucasoid population: KIR haplotypes contain between seven and eleven KIR genes. Immunogenetics, 54:221-229.
  • Young NT and Uhrberg M (2002). KIR shape peripheral cytotoxic repertoires through cell survival. Trends in Immunology 23:71-75.
Habilitation