Recent News

April 15, 2012
Teuta's paper on osmoregulation published in PLoS one.

December 31, 2011
Steven and Leon's paper on cell wall rotation and chiral peptidoglycan ordering accepted at PNAS.

December 1, 2011

September 20, 2011
Sabattical visitor Zhaomin Yang (Virginia Tech) will be with us for the fall semester to think about biophysical studies of Myxococcus S-motility. Welcome Zhaomin!

Publications

2012

Multiphase recovery of Escherichia coli to hyperosmotic shock [URL]

Pilizota, Shaevitz
PLoS One doi:10.1371/ journal.pone.0035205

Helical insertion of peptidoglycan produces elongation and chiral ordering of the bacterial cell wall [PDF+SI]

Wang, Furchtgott, Huang, Shaevitz
Proceedings of the National Academy of Sciences doi:10.1073/pnas.1117132109

Image analysis in fluorescence microscopy: bacterial dynamics as a case study [PDF]

van Teeffelen, Shaevitz, Gitai
BioEssays doi:10.1002/bies.201100148

2011

From individual cell motility to collective behaviors: insights from a prokaryote, Myxococcus xanthus [PDF]

Zhang, Ducret, Shaevitz, Mignot
FEMS Microbiology Reviews doi:10.1111/j.1574-6976.2011.00307.x


Direct measurement of stress-stiffening and turgor pressure in live bacterial cells [PDF] [SI]

Deng, Sun, Shaevitz
Physical Review Letters doi:10.1103/PhysRevLett.107.158101

The bacterial actin MreB rotates, and rotation depends on cell-wall assembly[PDF+SI]

van Teeffelen, Wang, Furchtgott, Huang,  Wingreen, Shaevitz, Gitai
Proceedings of the National Academy of Sciences doi: 10.1073/pnas.1108999108

Motor-driven Intracellular Transport Powers Bacterial Gliding Motility [PDF+SI]

Sun, Wartel, Cascales, Shaevitz, Mignot
Proceedings of the National Academy of Sciences doi:10.1073/pnas.1101101108

Femtosecond diffractive imaging of biological cells [PDF]

Seibert, Boutet, Svenda, Ekeberg, Maia, Bogan, Timneanu, Barty, Hau-Riege, Caleman, Frank, Benner, Lee, Marchesini, Shaevitz, Fletcher, Bajt, Andersson, Chapman, Hajdu
Journal of Physics B: Atomic, Molecular and Optical Physics doi:10.1088/0953-4075/43/19/194015

The structure and Function of Bacterial Actin Homologs [PDF]

Shaevitz and Gitai
Cold Spring Harbor Perspectives in Biology  doi: 10.1101/cshperspect.a000364

An actin-like cytoskeleton contributes to cell mechanics in bacteria [PDF] [SI]

Wang, Arellano-Santoyo, Combs, Shaevitz
Proceedings of the National Academy of Sciences doi: 10.1073/pnas.0911517107

Measuring the Bending Stiffness of Bacterial Cells Using an Optical Trap [HTML]

Wang, Arellano-Santoyo, Combs, Shaevitz
Journal of Visual Experiments doi: 10.3791/2012

A Parallel Product-Convolution approach for representing the depth varying Point Spread Functions in 3D widefield microscopy based on principal component analysis [PDF]

Arigovindan, Shaevitz, McGowan, Sedat, Agard
Optics Express doi:10.1364/OE.18.006461

The cytoskeleton: I-beams of the cell [PDF]

Shaevitz and Nørrelykke
Physics Today 

2009

The effect of aberrations on height calibration in three-dimensional microscopy and particle tracking [PDF]

Deng and Shaevitz
Applied Optics doi:10.1364/AO.48.001886


Bayesian Estimation of the Axial Position in Astigmatism-Based Three-Dimensional Particle Tracking [PDF]

Shaevitz
International Journal of Optics doi:10.1155/2009/896208

2008

Active and Passive Mechanisms of Intracellular Transport and Localization in Bacteria [PDF]

Mignot and Shaevitz
Current Opinions in Microbiology doi:10.1016/j.mib.2008.10.005

Slow stress propagation in adherent cells [PDF]

Rosenbluth, Crow, Shaevitz, Fletcher
Biophysical Journal doi:10.1529/biophysj.108.139139

Massively parallel X-ray holography [PDF]

Marchesini, Boutet, Sakdinawat, Bogan, Bajt, Barty, Chapman, Frank, Hau-Riege, Szoke, Cui, Shapiro, Howells, Spence, Shaevitz, Lee, Hajdu, Seibert
Nature Photonics doi:10.1038/nphoton.2008.154

Curvature and torsion in growing actin networks [PDF]

Shaevitz and Fletcher
Physical Biology doi:10.1088/1478-3975/5/2/026006

Super-resolution for a 3D world [PDF]

Shaevitz
Nature Methods doi:10.1038/nmeth0608-471


2007

Load fluctuations drive actin network growth [PDF]

Shaevitz and Fletcher
Proceedings of the National Academy of Sciences doi: 10.1073/pnas.0702601104

Enhanced three-dimensional deconvolution microscopy using a measured depth-varying point spread function [PDF]

Shaevitz and Fletcher
Journal of the Optical Society of America A doi:10.1364/JOSAA.24.002622

Evidence that Focal Adhesion Complexes Power Bacterial Gliding Motility [PDF]

Mignot, Shaevitz, Hartzell, Zusman
Science doi:10.1126/science.1137223

earlier papers

Direct observation of base-pair stepping by RNA polymerase [PDF]

Abbondanzieri, Greenleaf, Shaevitz, Landick, Block
Nature (2005)

Picocalorimetry of Transcription by RNA Polymerase [PDF]

Abbondanzieri, Shaevitz, Block
Biophysical Journal (2005) 

Statistical Kinetics of Macromolecular Dynamics [PDF]

Shaevitz, Schnitzer, Block
Biophysical Journal (2005)

Spiroplasma Swim by a Processive Change in Body Helicity [PDF]

Shaevitz, Lee, Fletcher
Cell (2005)

Backtracking by single RNA polymerase molecules observed at near-base-pair resolution [PDF]

Shaevitz, Abbondanzieri, Landick, Block
Nature (2003)

Probing the kinesin reaction cycle with a 2D optical force clamp [PDF]

Block, Asbury, Shaevitz, Lang
Proceedings of the National Academy of Sciences (2003)

An Automated Two-Dimensional Optical Force Clamp for Single Molecule Studies [PDF]

Lang, Asbury, Shaevitz, Block
Biophysical Journal (2002)