Dr. Samrat Mukhopadhyay, Ph.D.
Assistant Professor of Biology and Chemistry
Indian Institute of Science Education and Research (IISER), Mohali. Knowledge City, Sector 81, S.A.S. Nagar, Mohali-140306, Punjab, India. Location map: http://www.iisermohali.ac.in/LocationMohali.jpg
Research interests:
Protein Folding, Misfolding, Amyloid Biology, Fluorescence Spectroscopy, Single Molecule Biophysics & Nanoscale Imaging
For details click here. List of publications: (Total citations: > 550 h-index = 9)
*NEW* Our recent paper in Biophysical Jounal is featured in Faculty of 1000. http://f1000.com/13409028 18. "Structural and Dynmical Insights into the Molten-Globule form of Ovalbumin" M. Bhattacharya and S. Mukhopadhyay. J. Phys. Chem. B. 2012, 116, 520-531. http://pubs.acs.org/doi/abs/10.1021/jp208416d
17. "Chain Collapse of an Amyloidogenic Intrinsically Disordered Protein" N. Jain, M. Bhattacharya and S. Mukhopadhyay. Biophys. J. 2011, 101, 1720-1729. http://www.cell.com/biophysj/retrieve/pii/S0006349511009702 Featured in Faculty of 1000 http://f1000.com/13409028
16. "Insights into the Mechanism of Aggregation and Fibril Formation from Bovine Serum Albumin" M. Bhattacharya, N. Jain and S. Mukhopadhyay. J. Phys. Chem. B. 2011, 115, 4195–4205. http://pubs.acs.org/doi/abs/10.1021/jp111528c 15. "Studying Protein Misfolding and Aggregation using Fluorescence Spectroscopy" M. Bhattacharya and S.Mukhopadhyay* Reviews in Fluorescence 2011 (Invited review and will be published soon).
14. "pH-induced Conformational Isomerization of Bovine Serum Albumin Studied by Extrinsic and Intrinsic Protein Fluorescence" M. Bhattacharya, N. Jain, K. Bhasne, V. Kumari and S. Mukhopadhyay Journal of Fluorescence 2011, 21, 1083-1090. http://www.springerlink.com/content/g56h4hk23663q734/
13. "Kinetics of Surfactant-induced Aggregation of Lysozyme Studied by Fluorescence Spectroscopy" N. Jain, M. Bhattacharya and S. Mukhopadhyay. Journal of Fluorescence 2011, 21, 615-625. http://www.springerlink.com/content/f8662237w17652h2/ 12. "Direct and Selective Elimination of Specific Prions and Amyloids by 4,5-Dianilinophthalimide and Analogs" H. Wang, M.L. Duennwald, B.E. Roberts, L.M. Rozeboom, Y.L. Zhang, A.D. Steele, R. Krishnan, L.J. Su, D. Griffin, S. Mukhopadhyay, E.J. Hennessy, P. Weigele, B.J. Blanchard, J. King, A.A. Deniz, S.L. Buchwald, V.M. Ingram, S. Lindquist and J. Shorter. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 7159-7164. http://www.pnas.org/cgi/reprint/105/20/7159 11. "Single-Molecule Biophysics: At the Interface of Biology, Physics and Chemistry" A.A. Deniz, S. Mukhopadhyay and E.A. Lemke J. R. Soc. Interface 2008, 5, 15-45. http://www.journals.royalsoc.ac.uk/content/0x116338np247206/fulltext.pdf
Among the most read articles at JRSI 10. "A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures" S. Mukhopadhyay, R. Krishnan, E. A. Lemke, S. Lindquist and A.A. Deniz. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 2649-2654. http://www.pnas.org/cgi/reprint/104/8/2649.pdf 9. "Biomolecular structure and dynamics using fluorescence from single diffusing molecules" S. Mukhopadhyay and A.A. Deniz. J. Fluorescence 2007, 17, 775-783. http://www.springerlink.com/content/f251382u545551v2/fulltext.pdf 8. "Characterization of amyloid fibril formation by mapping residue-specific fluorescence dynamics" S. Mukhopadhyay, P. Nayak, J. B. Udgaonkar and G. Krishnamoorthy. J. Mol. Biol. 2006, 358, 935-942. http://dx.doi.org/10.1016/j.jmb.2006.02.006 7. "Advances in Molecular Hydrogels" S. Bhattacharya, U. Maitra, S. Mukhopadhyay, A. Srivastava in "Molecular Gels" 2006. P. Terech, R.G. Weiss (Eds.) Kluwer Academic Publishers, The Netherlands. http://www.springerlink.com/content/w3282465784v7036/
6. "Structure and Dynamics of a Molecular Hydrogel" S. Mukhopadhyay, Uday Maitra, Ira, G. Krishnamoorthy, J. Scmidt and Y. Talmon J. Am. Chem. Soc. 2004, 126, 15905-15914. http://pubs.acs.org/cgi-bin/article.cgi/jacsat/2004/126/i48/pdf/ja046788t.pdf
1. "Hydrophobic Pockets in a Non-polymeric Aqueous Gel: Observation of such a Gelation Process by Color Change" U. Maitra, S. Mukhopadhyay, A. Sarkar, P. Rao and S.S. Indi. Angew. Chem. Int. Ed. 2001, 40, 2281-2283. (Cited over 110 times). |
