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Research Interests

  • Computational Biology 
  • Machine learning
  • Bio-image Analysis 
  • Soft Computing
  • Cell Processor in Bioinformatics 

 

Current Research: 

  • Analysis of Ultra High-throughput sequence data generated by next generation sequencing platforms (Solexa).
  • Design of a novel computation approach for identification of different classes of endo-siRNA from small RNA data generated by next generation sequencing platforms.
  • Design of analysis pipeline for small RNA data.
  • Identification of RNA-editing sites from high-throughput sequence dataset.
  • Identification of S/MARs in Giardia Genome.


Past Research problems:

Bioinformatics 
    • Identification of repetitive structures
    • Identification and classification of G-protein coupled receptors (GPCRs) and nuclear receptors using support vector machine
    • Prediction of protein structural classes
    • Signal processing and statistical approaches for bio-molecular sequence analysis
    • Techniques for identification of protein coding regions
    • Development of pattern recognition approach for classification of DNA sequences into coding and non-coding patterns
 Machine Learning
    • Wavelet technique for feature construction
    • A novel three-stage method for pattern classification in Bioinformatics.
    • Support vector machine based classification for protein and DNA sequence classification.
    • Application of data-mining technique for protein structural and functional classification.
Cell Processor in Bioinformatics 
    • Protein coding region identification on Cell processor.  
    • Developing a novel parallel Smith-Waterman algorithm for Cell processor.

Soft Computing

    • Developing multi-swarm optimization technique and its application to RF component design.

Bio-image Analysis

    • Identification and classification of Cell  based on  NO2  production
    • Study NO2 production based using image analysis technique

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