Protein Sequence
>A6NDE4|RBY1B_HUMAN RNA-binding motif protein, Y chromosome, family 1 member B - Homo sapiens (Human)
MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFENPAD
AKNAAKDMNGKSLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSRGGTR
GWLPSQEGHLDDGGYTPDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGS
QGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYATNDGNHPSCQETRDYAPPSRGYAY
RDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSR
ETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDYAYRDYGHSSWD
EHSSRGYSYHDGYGEALGRDHSEHLSGSSYRDALQRYGTSHGAPPARGPRMSYGGSTCHA
YSNTRDRYGRSWESYSSCGDFHYCDREHVCRKDQRNPPSLGRVLPDPREAYGSSSYVASI
VDGGESRSEKGDSSRY
Primary Structure
Compute pI
Theoretical pI 9.96
Molecular weight 55834.60(Daltons)
Protparam
Formula C2369H3634N800O756S13
Sequence Length 496
Total Atoms 7572
Secondary Structure
GOR, HNN & SOPMA
|
GOR |
HNN |
SOPMA |
|||||||
|
Alpha Helix |
Extended Strand |
Random Coil |
Alpha Helix |
Extended Strand |
Random Coil |
Alpha Helix |
Extended Strand |
Beta Turn |
Random Coil |
| 6.45 |
15.93 |
77.62 |
7.66 |
7.26 |
85.08 |
7.26 |
10.48 |
6.85 |
75.40 |
Tertiary Structure Prediction
I-TASSER
3-D Structure predicted By I-tasser server(Ab initio method) = A6NDE4
#model : C-score TM-score RMSD (in Angstroms)A6NDE4 : -1.38 0.54+-0.15 10.5+-4.6
C-score is a confidence score of the I-TASSER predictions which is
typically in [-5,2]. TM-score and RMSD measure how close the model is
to the native structure and both are estimated based on the C-score.
TM-score is in [0,1] with a value >0.5 implying the model of correct
topology. The TM-score and RMSD estimations are made only for the first
model because absolute values of TM-score and RMSD for the lower-rank
models do not strongly correlate with the C-score. The models are
ranked based on the structure density of I-TASSER simulations. Please
cite following articles when you use the I-TASSER server:
1) Yang Zhang. I-TASSER server for protein 3D structure prediction.
BMC Bioinformatics, 9:40 (2008).
2) Yang Zhang. Template-based modeling and free modeling by
I-TASSER in CASP7. Proteins, 8: 108-117 (2007).
3) Sitao Wu, Jeffrey Skolnick, Yang Zhang. Ab initio modeling of
small proteins by iterative TASSER simulations. BMC Biology,
5:17 (2007).
Structure Validation
PROCHECK
Saves Result : Procheck summary Ramachandran Plot: Plot statistics
Function Prediction
|
Interproscan |
GOG |
Pfam |
Blast |
| RNA recognition motif, RNP-1, RBM1CTR, Nucleotide-binding, alpha-beta plait, Y chromosome RNA recognition motif | RNA-binding proteins (RRM domain) | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), RBM1CTR (NUC064) family, NF-X1 type zinc finger, Sulfakinin family, Follistatin | RRM, RNA recognition motif; ,RBM1CTR (NUC064) family |

