PURSOR: Balance and Health

 
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PURSOR Protocol


For fifteen years, I have been working on the abatement of addictive craving. The PURSOR protocol is now ready for dissemination and employment by practitioners. For the first time, the clinician has a therapeutic tool that manages craving for alcohol or stimulants using only natural neurotransmitter precursors. The previously refractory patient who has failed all other modalities can now have hope.

Dopamine (DA) and serotonin (5-HT) are crucial and ubiquitous monoamine neurotransmitters. That these monoamines act antipodally is not a new idea. In 1977, Mogilnicki et al. concluded that central serotonin may play an inhibitory role to dopamine and other catecholamines. More recently, Daw et al. flatly state the dorsal raphe serotonin system and the ventral tegmental and substantia nigra dopamine systems act as mutual opponents

Combined DA and 5-HT Agonist Protocols (CODAS)

The CODAS protocols have been used clinically and in animal studies. 

  • National Institute on Drug Abuse (NIDA & The DUAL DEFICIT MODEL

    In 1993, I called Richard Rothman at NIDA's Baltimore Addiction Center to inform him of my remarkable results with CODAS which he now refers to as the dual deficit model (DDM) of addiction. In 1993 Rothman and I published a letter suggesting FEN/PHEN remits cocaine craving as well.

    Rothman has pursued the DDM ever since. He has now 20 publications that cite my original work. Recognizing the FDA's strong bias against combination drug therapy, he has sought to find a single agent that will promote both DA and 5-HT, You can download a recent Rothman article here.

    I do not believe his use of a single agent to correct both DA and 5-HT deficits will be as successful as the use of dual agents. Experience with multiple patients has shown that quantitative deficits of the two monoamines, DA and 5-HT, are totally independent of each other. Furthermore, the deficit levels vary temporally in each individual due to a multitude of factors such as the season of the year, levels of stress and even the menstrual cycle. Rothman's approach is not plastic enough to ideally manage all the DA/5-HT deficit ratios found clinically. An independent agonist for each monoamine neurotransmitter is, in my opinion, mandatory to reach the widest population and achieve the best results.

  • PURSOR Protocol

    I started using the PURSOR protocol in 1997. This protocol utilizes the precursors of dopamine and serotonin, levodopa and 5-hydroxytryptophan (5-HTP). These two natural nonstandard amino acids are combined with a natural oil, sweeteners and flavoring agents and are administered in turn to the tongue. Initially, these suspensions are sweet and flavorful. In time, after amounts that vary individually, the tastes turn first bland and then unpleasant. After both have been administered to this endpoint in turn, the following phenomena take place in minutes:
      • If a drug or alcohol craving had been present, the craving completely disappears. Chronic treatment continues to keep addiction in control.
      • If the patient was suffering from an affective neuropsychiatric disorder such  as depression or anxiety, these two abate.
      • Allergic symptoms such as nasal congestion or wheezing clear up.

Medical Disorders

Long term treatment with CODAS has already produced other remarkable therapeutic effects on chronic disorders. The conditions with a star have responded well. Those without a * may respond  but have not been treated.

Immune Disorders

Neuropsychiatric

  • Affective

    • Anxiety*

    • Depression*

    • Hostility*

  • Obsessive/Compulsive*

  • Stress Disorders

    • Post-Traumatic Stress*

    • Gulf War Syndrome*

  • Traumatic Brain Injury

Miscellaneous

Pietr Hitzig, M.D.
phitz96@gmail.com

http://sites.google.com/site/pietrhitzig/Home
Baltimore, MD
443 231-6240



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