NSMAP: A Method for Spliced Isoforms Identification and Quantification from RNA-Seq

Introduction

NSMAP (Nonnegativity and Sparsity constrained Maximum A Posteriori ) is designed to identify and quantify isoforms from RNA-seq by incorporating a sparsity term into expression level estimation to enable isoform structure prediction and expression estimation simultaneously.

The usage of NSMAP is enclosed in the package.

Download NSMAP Package

NSMAP is developed by Zheng Xia and Xiaobo Zhou from The Methodist Hospital Research Institute.

Reference

Zheng Xia, Jianguo Wen, Chung-Che Chang, and Xiaobo Zhou, "NSMAP: A Method for Spliced Isoforms Identification and Quantification from RNA-Seq", 2011, BMC Bioinformatics, 12:162.