神经心理学与应用认知神经科学 

(NACN)实验室


2009年2月4日更新

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陈楚侨教授(Prof. Raymond C. K. Chan)

2001年获香港大学心理学系认知神经心理学专业哲学博士学位。他拥有康复科学专业资格,并曾在香港多间医院机构工作,专心于中风、脊椎受损、其它神经系统引发的疾病的患者及其家人的心理卫生、适应过程、生活素质等问题。近年更专心于神经心理学及认知神经科学研究。来國內工作前为香港大学精神病学系讲师。现为基础、应用心理学专业博士生导师、香港大学精神病学系荣誉副教授及香港大学行为健康教研中心荣誉研究学者。陈教授是SCI杂志“Neuropsychological Rehabilitation”的编委和“Clinical Rehabilitation”的编委顾问。同时亦是“心理科学进展”的编委。他亦是国际神经心理学会(International Neuropsychological Society)亚洲区代表。

研究兴趣

神经心理学、认知神经科学、临床心理量表编制、病人及其家人的心理卫生、适应过程、生活素质等问题

研究方法

神经心理测试 (Neuropsychological testing)
事件相关电位技术 (Event-related Potential technique)
結構及功能磁共振技术 (structural and functional MRI scans)
临床量表 (Clinical Ratings)
分子生物学與基因遗传分析 (Molecular biology and behavioural genetics)
社會認知干預 (Social cognition intervention) 

参与项目

百人计划研究项目 

国家自然科学基金(特异性脑损伤患者注意力转换和多重任务行为的实验研究, #30370485) (2004-2006)

香港与温哥华精神分裂症初期神经认知功能的远期比较研究(NARSAD Young Investigator Award,国际基金) (2003-3006)

国家自然科学基金(信息加工的多方式认知神经科学研究, #30470571) (2005-2007)

An international study of improving treatment for the most severely ill with schizophrenia: double-blind, placebo-controlled trial of risperidone augmentation of clozapine treatment (Stanley Foundation, 国际基金)(2003-2005)

Evidence based study on efficacy of carer group in early psychosis” and “Quality of life and Functional Outcome of first-episode schizophrenia (2003-2005)

在中国文化背景下香港精神分裂症病人执行性功能的本质与模式 (香港大学研究基金,完成) (2001-2002)

座右铭

学而不思则惘,思而不学则殆
做科研必须俱备”三心两意”的精神: 专心(focused) 、信心(confidence) 、恒心(persistence) 、诚意(passion) 、创意(creativity)

研究生及本科生义务工作

欢迎具有心理学、生命科学、计算机科学以及医学背景并对探讨脑功能与日常行为关系具浓厚兴趣的同学报考研究生或参与本科生义务工作。有兴趣参与有关研究领域的人直接与我们联络, 电子邮箱(rckchan@psych.ac.cn or rckchan2003@yahoo.com.hk)

代表论文

Chan, R. C. K.*, Gottesman, I. I. (2008). Neurological soft signs as candidate endophenotypes for schizophrenia: A shooting star or a northern star? Neuroscience and Biobehavioral Reviews,32, 957-971.

Chan, R. C. K.*, Shum, D., Toulopoulou, T., Chen, E. Y. H. (2008). Assessment of executive functions: Review of instruments and identification of critical issues. Archives of Clinical Neuropsychology, 23(2), 201-216.

Chan, R. C.K*., Wang, Y., Ma, Z., Hong, X., Yuan, Y., Yu, X., Li, Z., Shum, D., & Gong, Q. (2008). Objective measures of prospective memory do not correlate with subjective complaints in schizophrenia. Schizophrenia Research, 103, 229-239.

Rao, H*., Di, X., Chan, R. C. K.*, Ding, Y., Ye, B., Gao, D. (2008). A regulation role of the prefrontal cortex in the Fist-Edge-Palm task: evidence from functional connectivity analysis. NeuroImage, 41, 1345-1351.

Chan, R. C. K.*, Chen, E. Y. H.  (2007) Neurological abnormalities in Chinese patients with schizpohrenia. Behavioural Neurology, 18(3), 171-181.

 Wang, Y., Chan, R. C. K.*, Hong, X., Ma, Z., Yang, T., Guo, L., Yu, X., Li, Z., Yuan, Y., Gong, Q., & Shum, D. (2008). Prospective memory in schizophrena: Further clarification of nature of impairment. Schizophrenia Research, 105, 114-124.

Yang, B., Chan, R. C. K.*, Jing, J., Li, T., Sham, P., Chen, R. Y. L. (2007) A meta-analysis of association studies between the dopamine transporter gene and attention deficit hyperactivity disorder. American Journal of Medical Genetics Part B Neuropsychiatric Genetics , 144B(4), 541-550.

Chan, R. C. K., Guo, M., Zou, X., Li, D., Hu, Z., & Yang, B. (2006). Multitasking performance of Chinese children with ADHD. Journal of the International Neuropsychological Society, 12, 575-579.

Chan, R. C. K., Rao, H. Y., Chen, E. Y. H., Ye, B. B., & Zhang, C.(2006).  The neural basis of motor coordination soft signs: an fMRI study of healthy subjects. Neuroscience Letter, 398, 189-194.

Honer, W. G., Thornton, A. E., Chen, E. Y. H., Chan, R. C. K., Wong, J. O. Y., Bergmann, A., Falkai, P., Pomarol-Clotet, E., Mckenna, P. J., Stip, E., Willaims, R., MacEwan, G. W., Wasan, K., Procyshyn, R. (2006). A randomized controlled trial of antipsychotic polypharmacy: risperidone versus placebo augmentation of clozapine in refractory schizophrenia. New England Journal of Medicine, 354, 474-482.

Chan, R. C. K., Chen, E. Y. H., & Law, C. W. (2006). Specific executive dysfunction in patients with first-episode medication-naïve schizophrenia. Schizophrenia Research, 82(1), 51-64

Chan, R. C. K., Chen, E. Y. H., Cheung, E. F. C., Chen, R. Y. L., & Cheung, H. K. (2006) The components of executive functioning in a cohort of patients with chronic schizophrenia: a multiple single-case study design. Schizophrenia Research, 81(2-3), 173-189

Chan, R. C. K., Chen, R. Y. L., Chen, E.  Y. H., Hui, T. C. K., Cheung, E. F. C., Cheung, H. K., Sham, P., Li, T., & Collier, D. (2005). The differential clinical and neurocognitive profiles of COMTSNPrs165599 in schizophrenia. Journal of the International Neuropsychological Society, 11, 202-204

Chan, R. C. K. (2005) How severe should symptoms be before we say someone is suffering from postconcussion syndrome? An exploratory study with self-reported checklist using Rasch Analysis. Brain Injury, 19(13), 1117-1124

Chan, R. C. K. (2002). Attentional deficits in patients with persisting postconcussive complaints: general deficit or specific component deficits? Journal of Clinical and Experimental Neuropsychology,24(8), 1081-1093

Chan, R. C. K. (2001). Dysexecutive symptoms among the non-clinical sample: a study with the use of the Dysexecutive Questionnaire. British Journal of Psychology, 92(3), 551-565

Chan, R. C. K. (2001). Base-rate of postconcussion symptoms among non-clinical sample and its neuropsychological correlates. Clinical Rehabilitation, 15(3), 266-273

Chan, R. C. K. (2000). Attentional deficits in patients with closed head injuries: a further study to the discriminative validity of the Test of Everyday Attention. Brain Injury, 14(3), 227-236.