 45 Yongso-ro, Nam-Gu Department of Biomedical Engineering
Pukyong National University Busan 608-737, South Korea myunggi at pknu dot ac dot kr Phone: +82 51 629-5773 Fax: +82 51 629-5779
Positions and Employments
2011 - Present : Assistant Professor, Department of Biomedical Engineering, Pukyong National University 2010 - 2011 : Postdoctoral Fellow with Jeffrey J. Gray (advisor) and Marc Ostermeier, Department of Chemical and Biomolecular Engineering, Johns Hopkins University
2008 - 2010 : Postdoctoral Associate with Huan-Xiang Zhou (advisor) and Timothy A. Cross, National High Magnetic Field Laboratory Educations
2008 : Ph.D. in Computational Biophysics, Department of Physics, Florida State University Ph.D. Thesis : Dynamics of Biomolecules, Ligand Binding & Biological Functions (advisor: Huan-Xiang Zhou) 2000 : B.Sc. in Physics, Pukyong National University, South Korea Peer-reviewed Publications
[9] Cross TA, Sharma M, Yi M, Zhou HX (Feb., 2011) Influence of solubilizing environments on membrane protein structures. Trends Biochem Sci 36:117-125. (IF: 11.572) [8] Sharma M, Yi M, Dong H, Qin H, Peterson E, Busath DD, Zhou HX, Cross TA (Oct. 22, 2010)
Insight into the mechanism of the influenza A proton channel from a structure in a lipid bilayer. (PDB deposit: 2L0J) [7] Yi M, Cross TA, Zhou HX (Aug. 11, 2009)
Conformational heterogeneity of the M2 proton channel and a structural model for channel activation. Proc Natl Acad Sci USA 106:13311-13316. (IF: 9.380) BRIC (한국을 빛내는 사람들) [6] Dong GC, Chung PH, Chang KC, Jan PS, Hwang PI, Wu HB, Yi M, Zhou HX, Chen HM (Feb., 2009) Blocking effect of an immuno-suppressive agent, Cynarin, on CD28 of T-cell receptor. Pharm Res 26:375-381. (IF: 4.024) [5] Yi M, Nymeyer H, Zhou HX (Jul. 18, 2008) Test of the Gouy-Chapman theory for a charged lipid membrane by explicit-solvent molecular dynamics simulations. Phys Rev Lett 101:038103. (IF: 6.944) Faculty of 1000 Biology [4] Yi M, Cross TA, Zhou HX (Jul. 10, 2008) A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine. J Phys Chem B 112:7977-7979. (IF: 4.086) Cover Article [3] Yi M, Tjong H, Zhou HX (Jun. 17, 2008) Spontaneous conformational change and toxin binding in α7 nicotinic acetylcholine receptor: Insight into channel activation and inhibition. Proc Natl Acad Sci USA 105:8280-8285. (IF: 9.598) In This Issue BRIC (한국을 빛내는 사람들) [2] Li C, Yi M, Hu J, Zhou HX, Cross TA (Feb. 15, 2008) Solid-state NMR and MD simulations of the antiviral drug amantadine solubilized in DMPC bilayers. Biophys J 94:1295-1302. (IF: 4.627) [1] Bhattacharya N, Yi M, Zhou HX, Logan TM (Dec. 7, 2007) Backbone dynamics in an intramolecular prolylpeptide-SH3 complex from the diphtheria toxin repressor, DtxR. J Mol Biol 374:977-992. (IF: 4.890) Contributed Talks, Presentations and Abstracts Yi M, Zhou HX Oligomerization of amphipathic peptides in a membrane bilayer characterized by coarse-grained molecular dynamics simulations. Biophysical Society 54th Annual Meeting, San Francisco, CA, Feb. 2010, 2369 Yi M, Cross TA, Zhou HX Conformational heterogeneity of the M2 proton channel: A model for channel activation. Biophysical Society 53rd Annual Meeting, Boston, MA, Feb. 2009, 3448 Yi M, Tjong H, Zhou HX Spontaneous conformational changes and toxin binding in α7 nicotinic acetylcholine receptor: Insight into channel activation and inhibition. International Conference on Complex Networks : The Past 10 Years and Future, Seoul, South Korea, Dec. 2008 Yi M, Cross TA, Zhou HX Helix kinking, conformational heterogeneity, and blockage of the M2 proton channel: Roles of water molecules and amantadine binding. Biophysical Society 52nd Annual Meeting, Long Beach, CA, Feb. 2008, 202 Yi M, Tjong H, Zhou HX Spontaneous conformational changes and toxin binding in α7 nicotinic acetylcholine receptor: Insight into channel activation and inhibition. Biophysical Society 52nd Annual Meeting, Long Beach, Feb. 2008, 1421 Yi M, Li C, Cross TA, Zhou HX Molecular dynamics study of amantadine inhibition of the M2 ion channel of Influenza A in phospholipid bilayers. Biophysical Society 51st Annual Meeting, Baltimore, MD, Feb. 2007, 2652 YI M, Tjong H, Zhou HX Molecular dynamics study of amantadine inhibition of the M2 ion channel of Influenza A in phospholipid bilayers. Quantitative Computational Biophysics Workshop, Tallahassee, FL, Feb. 2007 Yi M, Carborne I, Cross TA, Zhou HX Calculation of pKa's for histidine at the center of the Influenza A M2 proton channel. Biophysical Society 50th Annual Meeting, Salt Lake City, UT, Feb. 2006, 935 Yi M, Bhattacharya N, Logan TM, Zhou HX Dynamics and intramolecular ligand binding of DtxR studied by MD simulations and NMR spectroscopy. American Physical Society 72nd annual meeting of the Southeastern Section (SESAPS), Gainesville, FL, Nov. 2005 Yi M, Bhattacharya N, Logan TM, Zhou HX Dynamics and binding kinetics of an intramolecular ligand in DtxR Biophysical Society 48th Annual Meeting, Baltimore, MD, Feb. 2004, 488 |