8:30 - 9:15 Registration 9:15 - 9:20 Markus Dahlem: Welcome & opening remarks Morning session I Ion dynamics during migraine Chair: Hugh R. Wilson 09:20 - 10:00 George Somjen: Why simulate SD? Empirical data and the search for their explanation 10:05 - 10:20 Wytse Wadman: Modeling Ionic Mechanisms in Spreading Depression 10:25 - 11:00 Coffee break Morning session II Potassium dynamics & excitability Chair: Uwe Heineman 11:00 - 11:15 Ernest Barreto: Ion concentration dynamics and neuronal excitability 11:20 - 11:35 Gerson Florence: Effects of depressed K+ currents caused by high [K+]o on the different stages of spreading depression 11:40 - 11:55 Flavio Fröhlich: Potassium dynamics: new insights on an old topic 12:00 - 12:15 Tony Gardner-Medwin: Spatial buffering of K+ in relation to SD models 12:20 - 13:45 Lunch break 13:45 - 14:45 Moderated discussions Jens Dreier Spreading depression, hypoxic depolarization, peri-infarct depolarization etc.: Processes of the same nature, need for a generic term? Afternoon session I Cellular and membrane dynamics Chair: Jens Dreier 14:45 - 15:00 Oscar Herreras: Polarization gradients and current loops within single cells raise the DC potential in spreading depression: from single channels to macroscopic fields. 15:05 - 15:20 Thomas Heimburg: Action potentials as electromechanical pulses 15:25 - 15:40 Rubem C.A. Guedes: Effects of AC- and DC-electrical brain stimulation on CSD 15:45 - 16:45 Coffee break & Discussion Afternoon session II Functional abnormalities in channel mutations Chair: Alfred Lehmenkühler 16:45 - 17:00 Daniela Pietrobon: Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in CaV2.1 knockin migraine mouse models. 17:05 - 17:20 Thomas Friedrich: Functional abnormalities due to Na,K-ATPase 2-subunit mutations identified in familial hemiplegic migraine type 2. 17:25 - 17:40 Gianluca Coppola: New approaches to analysis of high frequency somatosensory oscillations in healthy subjects and migraine patients. Next Day | Home |