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Epi & Ctrl Infect Dis


Public Health 253B: Epidemiology & Control of Infectious Diseases is a one semester advanced introduction to the epidemiology and control of infectious diseases. The course is taught from the perspective public health communicable disease control officers: frontline practitioners that detect, investigate, control, and prevent infectious diseases in communities. The lectures are given by public health communicable disease and academic experts that practice, teach, investigate, or conduct research in their specific areas. The course will emphasize (1) core concepts in infectious disease transmission mechanisms, dynamics, and containment; (2) evidence-based approaches to designing and implementing infectious disease control and prevention measures; and (3) epidemiologic methods for investigating infectious diseases.

Course syllabus can be downloaded here (PDF). For roster, email archive, and drop boxes go to http://bspace.berkeley.edu.

Course time and location: Mondays, 10:00am--1:00pm (class begins 15 minutes after the hour, and ends 15 minutes before the hour) at 1918 University Avenue, 4th Floor (between Milvia and MLK).


Contents

  1. 1 (01/26) Epidemiologic Concepts for the Controlling of Infectious Diseases
  2. 2 (02/02) Designing Epidemiologic Studies to Assess Vaccine Effects
  3. 3 (02/09) Public Health and Hospital Surveillance
  4. 4 (02/23) Mathematical Modeling of Infectious Diseases
  5. 5 (03/02) Epidemiology and Control of Tuberculosis
  6. 6 (03/09) Conducting an Outbreak Investigation in 7 steps (or less)
  7. 7 (03/16) Epidemiology and Control of Selected Vector-borne Infectious Diseases
  8. 8 (03/30) Epidemiology and Control of Sexually Transmitted Infections
  9. 9 (04/06) Selected Topics in Vaccine-Preventable Infectious Diseases
  10. 10 (04/13) Biology, Epidemiology, and Control of Malaria
  11. 11 (04/20) Intentional Microbial Threats: Detection, Investigation, and Response
  12. 12 (04/27) Anti-microbial Resistance
  13. 13 (05/04) Epidemiology & Prevention of HIV transmission
  14. 14 (05/11) Final Exam Quiz & submit Quick Reference Guide

(01/26) Epidemiologic Concepts for the Controlling of Infectious Diseases

Concepts for the Control and Prevention of Infectious Diseases (Tomás Aragón)

Required readings
  • *** Aragón TJ. Epidemiologic Concepts for the Prevention and Control of Infectious Diseases
    [Slides] | [Handout] | [Chapter]
  • *** Pirofski L, Casadevall A. The meaning of microbial exposure, infection, colonisation, and disease in clinical practice. Lancet Infect Dis. 2002;2:628-635 (PMID: 12383613)
  • *** Musher DM. How contagious are common respiratory tract infections? N Engl J Med. 2003 Mar 27;348(13):1256-66. Review. (PMID: 12660390)
  • *** Musher DM, Musher BL. Contagious acute gastrointestinal infections. N Engl J Med. 2004 Dec 2;351(23):2417-27. Review. (PMID: 15575058)
  • *** Roy CJ, Milton DK. Airborne transmission of communicable infection--the elusive pathway. N Engl J Med. 2004 Apr 22;350(17):1710-2. (PMID: 15102996)
  • *** Svoboda T, Henry B, Shulman L, et al. Public health measures to control the spread of the severe acute respiratory syndrome during the outbreak in Toronto. N Engl J Med. 2004 Jun 3;350(23):2352-61. (PMID: 15175437)
  • *** Weinstein RA. Planning for epidemics--the lessons of SARS. N Engl J Med. 2004 Jun 3;350(23):2332-4. (PMID: 15175434)
  • *** Frieden TR, Das-Douglas M, Kellerman SE, Henning KJ. Applying public health principles to the HIV epidemic. N Engl J Med. 2005 Dec 1;353(22):2397-402. (PMID: 16319391)
Additional readings
  • Real LA, Biek R. Infectious disease modeling and the dynamics of transmission. Curr Top Microbiol Immunol. 2007;315:33-49. Review. (PMID: 17848059)
  • Brankston, G.; Gitterman, L.; Hirji, Z.; Lemieux, C. & Gardam, M. Transmission of influenza A in human beings. Lancet Infect Dis. 2007:7;257-265 (PMID: 17376383)
  • Goldmann DA. Transmission of viral respiratory infections in the home. Pediatr Infect Dis J. 2000 Oct;19(10 Suppl):S97-102. Review. (PMID: 11052396)
  • Mangili A, Gendreau MA. Transmission of infectious diseases during commercial air travel. Lancet. 2005 Mar 12-18;365(9463):989-96. Review. (PMID: 15767002)
  • Hayes EB, Komar N, Nasci RS, Montgomery SP, O'Leary DR, Campbell GL. Epidemiology and transmission dynamics of West Nile virus disease. Emerg Infect Dis. 2005 Aug;11(8):1167-73. (PMID: 16102302)
  • Rangel JM, Sparling PH, Crowe C, Griffin PM, Swerdlow DL. Epidemiology of Escherichia coli O157:H7 outbreaks, United States, 1982-2002. Emerg Infect Dis. 2005 Apr;11(4):603-9. (PMID: 15829201)

Epidemiologic approach for public health action (Tomás Aragón)

Required readings
  • *** Aragón TJ. The Epidemiologic Approach: Steps to Public Health Action
    [Slides] | [Handout]

Homework #1: Due Monday, February 9, 2009

(02/02) Designing Epidemiologic Studies to Assess Vaccine Effects

Designing Epidemiologic Studies to Assess Vaccine Effects (Tomás Aragón & Wayne Enanoria)

Required readings
  • *** Aragon TJ. Measuring vaccine effects on infectious diseases
    [Slides] | [Handout]
  • Chen RT, Orenstein WA. Epidemiologic methods in immunization programs. Epidemiol Rev. 1996;18(2):99-117. Review. (PMID: 9021306)
  • Halloran ME, Struchiner CJ. Study designs for dependent happenings. Epidemiology. 1991 Sep;2(5):331-8. (PMID: 1742381)
  • *** Halloran ME, Struchiner CJ, Longini IM Jr. Study designs for evaluating different efficacy and effectiveness aspects of vaccines. Am J Epidemiol. 1997 Nov 15;146(10):789-803. Review. (PMID: 9384199)
  • Halloran ME, Longini IM Jr, Struchiner CJ. Design and interpretation of vaccine field studies. Epidemiol Rev. 1999;21(1):73-88. Review. (PMID: 10520474)
  • Haber M. Estimation of the direct and indirect effects of vaccination. Stat Med. 1999 Aug 30;18(16):2101-9. (PMID: 10441766)
Student MMWRs
  • [Eddy S] Clark JL, Konda KA, Segura ER, Salvatierra HJ, Leon SR, Hall ER, Caceres CF, Klausner JD, Coates TJ. Risk factors for the spread of HIV and other sexually transmitted infections among men who have sex with men infected with HIV in Lima, Peru. Sex Transm Infect. 2008 Nov;84(6):449-54. (PMID: 19028945)
Additional resources
  • Préziosi MP, Halloran ME. Effects of pertussis vaccination on transmission: vaccine efficacy for infectiousness. Vaccine. 2003 May 16;21(17-18):1853-61. (PMID: 12706669)
  • Torvaldsen S, McIntyre PB. Observational methods in epidemiologic assessment of vaccine effectiveness. Commun Dis Intell. 2002;26(3):451-7. Review. (PMID: 12416713)

Homework #2: Due Monday, February 23, 2009

(02/09) Public Health and Hospital Surveillance

Public Health Surveillance: Detecting and Monitoring (Michael Samuel)

Required readings
  • *** Samuel M. Public Health Surveillance (Download Slides)
  • CDC. Multistate Outbreak of Salmonella Infections Associated with Peanut Butter and Peanut Butter–Containing Products --- United States, 2008-2009. MMWR Morb Mortal Wkly Rep. 2009 Jan 29;58-Early Release (PMID: 19194370)
  • WHO. Surveillance standards for antimicrobial resistance. WHO/CDS/CSR/DRS/2001/5
    (Download)
  • WHO. Recommended Surveillance Standards: ANNEX 1. Software free and in the public domain. WHO/CDS/CSR/ISR/99.2. 147. (Download)
  • CDC. Framework for evaluating public health surveillance systems for early detection of outbreaks: Recommendations from the CDC Working Group. MMWR Recomm Rep. 2004 May 7;53(RR-5):1-11. (PMID: 15129191)
Additional readings
  • CDC. Case definitions for infectious conditions under public health surveillance. Centers for Disease Control and Prevention. MMWR Recomm Rep. 1997 May 2;46(RR-10):1-55. (PMID: 9148133)
  • CDC. Framework for program evaluation in public health. MMWR Recomm Rep. 1999 Sep 17;48(RR-11):1-40. (PMID: 10499397)
  • CDC. Updated guidelines for evaluating public health surveillance systems: Recommendations from the Guidelines Working Group. MMWR Recomm Rep. 2001 Jul 27;50(RR-13):1-35. (PMID: 18634202)
  • Dato V, Wagner MM, Fapohunda A. How outbreaks of infectious disease are detected: a review of surveillance systems and outbreaks. Public Health Rep. 2004 Sep-Oct;119(5):464-71. (PMID: 15313109)
  • Perry HN, McDonnell SM, Alemu W, Nsubuga P, Chungong S, Otten MW Jr, Lusamba-dikassa PS, Thacker SB. Planning an integrated disease surveillance and response system: A matrix of skills and activities. BMC Med. 2007 Aug 15;5:24. (PMID: 17697387)
Student MMWRs
  • [Mary H] CDC. Potential effects of electronic laboratory reporting on improving timeliness of infectious disease notification--Florida, 2002-2006. MMWR Morb Mortal Wkly Rep. 2008 Dec 12;57(49):1325-8. (PMID: 19078921)
  • [Scott B] TO BE RESCHEDULED
  • [Angel W] World Health Organization. Update on avian influenza A (H5N1) virus infection in humans. N Engl J Med. 2008 Jan 17;358(3):261-73. (PMID: 18199865)

Surveillance for Healthcare-Associated Infections (HAIs) (Tomás Aragón)

Optional readings
  • Horan TC, Andrus M, Dudeck MA.  CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting.  Am J Infect Control. 2008 Jun;36(5):309-32. Erratum in: Am J Infect Control. 2008 Nov;36(9):655. (PMID: 18538699)
  • Klevens RM, Edwards JR, Richards CL Jr, Horan TC, Gaynes RP, Pollock DA, Cardo DM.  Estimating health care-associated infections and deaths in U.S. hospitals, 2002.  Public Health Rep. 2007 Mar-Apr;122(2):160-6. (PMID: 17357358)
  • Tokars JI, Richards C, Andrus M, Klevens M, Curtis A, Horan T, Jernigan J, Cardo D.  The changing face of surveillance for health care-associated infections.  Clin Infect Dis. 2004 Nov 1;39(9):1347-52. Epub 2004 Oct 6. (PMID: 15494912)

(02/23) Mathematical Modeling of Infectious Diseases

Mathematical Modeling of Infectious Diseases (Travis Porco)

Required readings
  • *** Porco TC. Mathematical Modeling of Infectious Disease (Download PDF)
  • *** Garnett GP. Sex Transm Infect. 2002 Feb;78(1):7-12. An introduction to mathematical models in sexually transmitted disease epidemiology. (PMID: 11872850)
  • Garnett GP. Role of herd immunity in determining the effect of vaccines against sexually transmitted disease. J Infect Dis. 2005 Feb 1;191 Suppl 1:S97-106. (PMID: 15627236)
  • Aral SO. Determinants of STD epidemics: implications for phase appropriate intervention strategies. Sex Transm Infect. 2002 Apr;78 Suppl 1:i3-13. (PMID: 12083444)
Additional readings
  • Basu S, Andrews JR, Poolman EM, Gandhi NR, Shah NS, Moll A, et al. Prevention of nosocomial transmission of extensively drug-resistant tuberculosis in rural South African district hospitals: an epidemiological modelling study. Lancet. 2007 Oct 27;370(9597):1500-7. (PMID: 17964351)
  • Anderson RM, Fraser C, Ghani AC, Donnelly CA, Riley S, Ferguson NM, Leung GM, Lam TH, Hedley AJ. Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic. Philos Trans R Soc Lond B Biol Sci. 2004 Jul 29;359(1447):1091-105. (PMID: 15306395)

Student MMWRs

  • [Stephanie T] Climate Change May Alter Malaria Patterns. Science Daily (Feb. 17, 2009) (View HTML Page)
  • [Courtney Z] MacIntyre CR, Cauchemez S, Dwyer DE, Seale H, Cheung P, Browne G, Fasher M, Wood J, Gao Z, Booy R, Ferguson N. Emerg Infect Dis. 2009 Feb;15(2):233-41. Face mask use and control of respiratory virus transmission in households. (PMID: 19193267)
  • [Rachel K] Tong S, Conrardy C, Ruone S, Kuzmin IV, Guo X, Tao Y, et al. Detection of novel SARS-like and other coronaviruses in bats from Kenya. Emerg Infect Dis [serial on the Internet]. 2009 Mar [2009-02-20]. (Available from http://www.cdc.gov/EID/content/15/3/482.htm)

(03/02) Epidemiology and Control of Tuberculosis

Epidemiology and Control of Tuberculosis (Jennifer Flood)

Required readings
  • *** Flood J. Tuberculosis Control in California (Download Slides)
  • *** Maartens G, Wilkinson RJ. Tuberculosis. Lancet. 2007 Dec 15;370(9604):2030-43. Review. (PMID: 17719083)
  • Banerjee R, Allen J, Westenhouse J, Oh P, Elms W, Desmond E, Nitta A, Royce S, Flood J. Extensively drug-resistant tuberculosis in california, 1993-2006. Clin Infect Dis. 2008 Aug 15;47(4):450-7. (PMID: 18616396)
  • Taylor Z, Nolan CM, Blumberg HM; American Thoracic Society; Centers for Disease Control and Prevention; Infectious Diseases Society of America. Controlling tuberculosis in the United States. Recommendations from the American Thoracic Society, CDC, and the Infectious Diseases Society of America. MMWR Recomm Rep. 2005 Nov 4;54(RR-12):1-81. (PMID: 16267499) Erratum in: MMWR Morb Mortal Wkly Rep. 2005 Nov 18;54(45):1161. 
Student MMWRs
  • [Jennifer H] CDC. Update: influenza activity - United States, September 28, 2008--January 31, 2009. MMWR Morb Mortal Wkly Rep. 2009 Feb 13;58(5):115-9. (PMID: 19214161)
  • [Katherine H] 
    • McNeil DG. Court Says Vaccine Not to Blame for Autism. New York Times. February 13, 2009 (View HTML Page)
    • Gerber JS, Offit PA. Vaccines and Autism: A Tale of Shifting Hypotheses. Clin Infect Dis. 2009 Jan 7. [Epub ahead of print] (PMID: 19128068)
  • [Olivia C] Dept of Health and Human Services & Dept of Homeland Security. Guidance on Allocating and Targeting Pandemic Influenza Vaccine. (Download PDF)

(03/09) Conducting an Outbreak Investigation in 7 steps (or less)

Conducting an Outbreak Investigation in 7 Steps (or less) (Tomás Aagón)

Required preparation before class
Required readings
  • *** Aragon TJ, Enanoria WT, Reingold A. Conducting an outbreak investigation in 7 steps (or less). (Quick Ref Guide)
  • *** Reingold AL. Outbreak investigations--A perspective. Emerg Infect Dis 1998;4(1):21-7. (PMID: 9452395)
  • NCCPHP. Overview of Outbreak Investigations. FOCUS on Field Epidemiology. (Newsletter | Discussion)
  • NCCPHP. Anatomy and Physiology of an Outbreak FOCUS on Field Epidemiology. (Newsletter | Discussion)
  • NCCPHP. Embarking on an Outbreak FOCUS on Field Epidemiology. (Newsletter | Discussion)
  • Goodman RA, Buehler JW, Koplan JP. The epidemiologic field investigation: science and judgment in public health practice. Am J Epidemiol. 1990 Jul;132(1):9-16. (PMID: 2356818)
Additional Readings
Student MMWRs
  • [Anja T] Krause G, et al. Prioritisation of infectious diseases in public health--call for comments. Euro Surveill. 2008 Oct 2;13(40). pii: 18996. (PMID: 18831949)
  • [Katherine T-N]
    • Koenig R. Public health. International groups battle cholera in Zimbabwe. Science. 2009 Feb 13;323(5916):860-1. (PMID: 19213882)
    • Zuckerman JN, Rombo L, Fisch A. The true burden and risk of cholera: implications for prevention and control. Lancet Infect Dis. 2007 Aug;7(8):521-30. Review. (PMID: 17584531)

(03/16) Epidemiology and Control of Selected Vector-borne Infectious Diseases

Epidemiology and Control of Selected Vector-borne Infectious Diseases (Curtis Fritz & Anne Kjemtrup)

Required readings
Additional readings
  • Reisen W, Brault AC. West Nile virus in North America: Perspectives on epidemiology and intervention. Pest Manag Sci. 2007 Jul;63(7):641-6. (PMID: 17373672)
  • Prentice MB, Rahalison L. Plague. Lancet. 2007 Apr 7;369(9568):1196-207. (PMID: 17416264)
  • CDC 2006. Human plague--four states, 2006. MMWR Morb Mortal Wkly Rep. 2006 Sep 1;55(34):940-3. (PMID: 16943764)
  • Vázquez M, Muehlenbein C, Cartter M, Hayes EB, Ertel S, Shapiro ED. Effectiveness of personal protective measures to prevent Lyme disease. Emerg Infect Dis. 2008 Feb;14(2):210-6. (PMID: 18258112)
  • Klein SL, Calisher CH. Emergence and persistence of hantaviruses. Curr Top Microbiol Immunol. 2007;315:217-52. (PMID: 17848067)

Student MMWRs

  • [Heather Z] 
    • Avilés W, Ortega O, Kuan G, Coloma J, Harris E. Quantitative assessment of the benefits of specific information technologies applied to clinical studies in developing countries. Am J Trop Med Hyg. 2008 Feb;78(2):311-5. (PMID: 18256435)
    • Avilés W, Ortega O, Kuan G, Coloma J, Harris E. Integration of information technologies in clinical studies in Nicaragua. PLoS Med. 2007 Oct;4(10):1578-83. (PMID: 17958461)
  • [Liana C] CDC. Methicillin-resistant Staphylococcus aureus skin infections from an elephant calf--San Diego, California, 2008. MMWR Morb Mortal Wkly Rep. 2009 Mar 6;58(8):194-8. (PMID: 19265780 [HTML] [PDF])

(03/30) Epidemiology and Control of Sexually Transmitted Infections

Epidemiology and Control of Sexually Transmitted Infections (Gail Bolan)

Required readings
  • *** Bolan G. Emerging Issues in STD Prevention and Control, 2009. (Download Slides)
  • Low N, Broutet N, Adu-Sarkodie Y, Barton P, Hossain M, Hawkes S. Global control of sexually transmitted infections. Lancet. 2006 Dec 2;368(9551):2001-16. Review. (PMID: 17141708)
  • Ward H. Prevention strategies for sexually transmitted infections: importance of sexual network structure and epidemic phase. Sex Transm Infect. 2007 Aug;83 Suppl 1:i43-49. Epub 2007 Mar 27. Review. (PMID: 17389716)
  • Donovan B. Sexually transmissible infections other than HIV. Lancet. 2004 Feb 14;363(9408):545-56. Review. (PMID: 14975619)
Additional readings
  • CDC. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep. 2006 Aug 4;55(RR-11):1-94. (PMID: 16888612 [HTML] [PDF]) Erratum in: MMWR Recomm Rep. 2006 Sep 15;55(36):997. (View HTML)
  • Please note update: CDC. Update to CDC's sexually transmitted diseases treatment guidelines, 2006: Fluoroquinolones no longer recommended for treatment of gonococcal infections. MMWR Morb Mortal Wkly Rep. 2007 Apr 13;56(14):332-6. (PMID: 17431378)

(04/06) Selected Topics in Vaccine-Preventable Infectious Diseases

Pandemic Influenza Preparedness (Harvey Kayman, CDPH)

Required Readings
  • *** Kayman H. (2009) Pandemic Influenza Preparedness (Download Slides)
  • *** Belshe RB. The origins of pandemic influenza--lessons from the 1918 virus. N Engl J Med. 2005 Nov 24;353(21):2209-11.  (PMID: 16306515)
  • *** Monto AS. The risk of seasonal and pandemic influenza: Prospects for control. Clin Infect Dis. 2009 Jan 1;48 Suppl 1:S20-5. Review. (PMID: 19067611)
  • *** Monto AS, Whitley RJ. Seasonal and pandemic influenza: A 2007 update on challenges and solutions. Clin Infect Dis. 2008 Apr 1;46(7):1024-31. Review. (PMID: 18444819)
  • Markel H, Lipman HB, Navarro JA, Sloan A, Michalsen JR, Stern AM, Cetron MS. Nonpharmaceutical interventions implemented by US cities during the 1918-1919 influenza pandemic. JAMA. 2007 Aug 8;298(6):644-54. Erratum in: JAMA. 2007 Nov 21;298(19):2264. (PMID: 17684187)
  • Peiris JS, de Jong MD, Guan Y. Avian influenza virus (H5N1): a threat to human health. Clin Microbiol Rev. 2007 Apr;20(2):243-67. Review. (PMID: 17428885)

Community Infection Control (Kathleen Harriman, CDPH)

Required Readings
  • *** Harriman K. (2009) Community Infection Control (Download Slides)
  • *** Brankston G, Gitterman L, Hirji Z, Lemieux C, Gardam M. Transmission of influenza A in human beings. Lancet Infect Dis. 2007 Apr;7(4):257-65. Review. (PMID: 17376383) 
  • *** Tellier R. Review of aerosol transmission of influenza A virus. Emerg Infect Dis. 2006 Nov;12(11):1657-62. Review. (PMID: 17283614)

Student MMWRs

  • [Sam G] 
    • CDC. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep. 2006 Aug 4;55(RR-11):1-94. (PMID: 16888612 [HTML] [PDF]) Erratum in: MMWR Recomm Rep. 2006 Sep 15;55(36):997. (View HTML)
    • Please note update: CDC. Update to CDC's sexually transmitted diseases treatment guidelines, 2006: Fluoroquinolones no longer recommended for treatment of gonococcal infections. MMWR Morb Mortal Wkly Rep. 2007 Apr 13;56(14):332-6. (PMID: 17431378)
  • [Wendy V] 
    • CDC. Simian Malaria in a U.S. Traveler --- New York, 2008. MMWR Morb Mortal Wkly Rep. 2009 Mar 13;58(09):229-32. (View HTML)
    • Cox-Singh J, Singh B. Knowlesi malaria: Newly emergent and of public health importance? Trends in Parasitology. 2006;24(9):406-10 (Download PDF)

(04/13) Biology, Epidemiology, and Control of Malaria

Biology, Epidemiology, and Control of Malaria (Rosenthal & Dorsey)

Required reading
  • *** Rosenthal P. (2009) Malaria: It's Back! (Download Slides)
  • *** Dorsey G. (2009) Pitfalls in Estimating the Burden of Malaria in Uganda: The Uganda Malaria Surveillance Project (Download Slides)
  • *** Greenwood BM, Bojang K, Whitty CJ, Targett GA. Lancet. Malaria. 2005 Apr 23-29;365(9469):1487-98. (PMID: 15850634)
  • Greenwood BM, Fidock DA, Kyle DE, Kappe SH, Alonso PL, Collins FH, Duffy PE. Malaria: progress, perils, and prospects for eradication. J Clin Invest. 2008 Apr;118(4):1266-76. (PMID: 18382739)
Student MMWRs
  • [Agnes C] CDC. Recommended Immunization Schedules for Persons Aged 0 Through 18 Years --- United States, 2009. MMWR Morb Mortal Wkly Rep. 2009 2 Jan;57(51&52);Q-1-Q-4 . (View HTML page | View HTML Erratum)

(04/20) Intentional Microbial Threats: Detection, Investigation, and Response

Intentional Microbial Threats: Detection, Investigation, and Response (Debra Gilliss)

Required readings
  • *** Gilliss D. (2009) Preparing for Intentional Microbial Threats (Part 1): Detection, Investigation, and Response (Download Slides)
  • *** Gilliss D & Pan E. (2009) Preparing for Intentional Microbial Threats (Part 2): Agents of Concern (Download Slides)
  • *** Rotz LD, Khan AS, Lillibridge SR, Ostroff SM, Hughes JM. Public health assessment of potential biological terrorism agents. Emerg Infect Dis. 2002 Feb;8(2):225-30. (PMID: 11897082)
  • *** Inglesby TV, O'Toole T, Henderson DA, et al. Anthrax as a biological weapon, 2002: updated recommendations for management. JAMA. 2002;287(17):2236-52. Erratum in: JAMA 2002 Oct 16;288(15):1849. (PMID: 11980524)
  • *** Arnon SS, Schechter R, Inglesby TV, et al. Botulinum toxin as a biological weapon: medical and public health management. JAMA. 2001;285(8):1059-70. Erratum in: JAMA 2001 Apr 25;285(16):2081. (PMID: 11209178)
  • *** Henderson DA, Inglesby TV, Bartlett JG, et al. Smallpox as a biological weapon: medical and public health management. JAMA. 1999 Jun 9;281(22):2127-37. (PMID: 10367824)
  • *** Inglesby TV, Dennis DT, Henderson DA, et al. Plague as a biological weapon: medical and public health management. JAMA. 2000;283(17):2281-90. (PMID: 10807389)
  • *** Borio L, Inglesby T, Peters CJ, et al. Hemorrhagic fever viruses as biological weapons: medical and public health management. JAMA. 2002;287(18):2391-405. (PMID: 11988060)
  • *** Audi J, Belson M, Patel M, Schier J, Osterloh J. Ricin poisoning: a comprehensive review. JAMA. 2005;294(18):2342-51. (PMID: 16278363)
Additional readings
  • Dennis DT, Inglesby TV, Henderson DA, et al. Tularemia as a biological weapon: medical and public health management. JAMA. 2001;285(21):2763-73. (PMID: 11386933)
Student MMWRs
  • [Kanwar SJ] CDC. Update: progress toward global eradication of dracunculiasis, January 2007-June 2008. MMWR Morb Mortal Wkly Rep. 2008 Oct 31;57(43):1173-6. (PMID: 18971919)
  • [Scott B] Ren A, Louie B, Rauch L, Castro L, Liska S, Klausner JD, Pandori MW. Screening and confirmation of human immunodeficiency virus type 1 infection solely by detection of RNA. J Med Microbiol. 2008 Oct;57(Pt 10):1228-33. (PMID: 18809550)
  • [Michelle C] CDC.
    • Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2007 Mar 23;56(RR-2):1-24. (PMID: 17380109)
    • HPV Vaccine: Introduced Legislation 2009-2010 (View HTML)

(04/27) Anti-microbial Resistance

Community-acquired Methicillin-resistant Staphylococcus Aureus (Eric Pan, 10:15a-11:05a)

Optional readings
  • Zetola N, Francis JS, Nuermberger EL, Bishai WR. Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat. Lancet Infect Dis. 2005 May;5(5):275-86. (PMID: 15854883)
  • Grundmann H, Aires-de-Sousa M, Boyce J, Tiemersma E. Emergence and resurgence of methicillin-resistant Staphylococcus aureus as a public-health threat. Lancet. 2006 Sep 2;368(9538):874-85. (PMID: 16950365)
  • Gorwitz RJ. A review of community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections. Pediatr Infect Dis J. 2008 Jan;27(1):1-7. (PMID: 18162929)
  • Miller LG, Diep BA. Clinical practice: colonization, fomites, and virulence: rethinking the pathogenesis of community-associated methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis. 2008 Mar 1;46(5):752-60. (PMID: 18220477)
  • Daum RS. Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. N Engl J Med. 2007 Jul 26;357(4):380-90. (PMID: 17652653). Erratum in: N Engl J Med. 2007 Sep 27;357(13):1357. (Download Erratum)

Antimicrobial Resistance in the Hospital Setting (Lisa Winston, 11:15a-12:05p)

Required readings
  • *** Winston L. Hospital Infection Control and Antibiotic Resistance (Download slides)
  • *** Mulvey MR, Simor AE. Antimicrobial resistance in hospitals: how concerned should we be? CMAJ. 2009 Feb 17;180(4):408-15. (PMID: 19221354)

(05/04) Epidemiology & Prevention of HIV transmission

Epidemiology & Prevention of HIV transmission (Grant Colfax & Henry Raymon)

Required readings
  • *** Frieden TR, Das-Douglas M, Kellerman SE, Henning KJ. Applying public health principles to the HIV epidemic. N Engl J Med. 2005 Dec 1;353(22):2397-402. (PMID: 16319391)

(05/11) Final Exam Quiz & submit Quick Reference Guide