Publications

Lu C, Ding F, Ke A. Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring. Submitted.

Lu C, Smith AM, Fuchs RT, Ding F, Rajashankar K, Henkin TM, Ke A. Crystal structures of the SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism. Nature Structural & Molecular Biology. 2008 May;15:1076-1083.

Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A. Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing. Proc Natl Acad Sci U S A. 2007 Oct 23;104:16844-16849.

Ke A, Ding F, Batchelor JD, Doudna JA. Structural roles of monovalent cations in the HDV ribozyme. Structure. 2007 Mar;15(3):281-7.

Wu S,

Wu S, Ke A, Doudna JA. A fast and efficient procedure to produce scFvs specific for large macromolecular complexes. J. Immunol Methods. 2007 Jan 10;318(1-2):95-101. Spanggord RJ, Siu F,

Spanggord RJ, Siu F, Ke A, Doudna JA. RNA-mediated interaction between the peptide-binding and GTPase domains of the signal recognition particle. Nature Structural & Molecular Biology. 2005 Dec;12(12):1116-22. Epub 2005 Nov 20.

Ke A, Doudna JA (2005), Catalytic strategies of self-cleaving ribozymes: Relics of an RNA world? The RNA World, 3rd Edition. (Book chapter)

Ke A, Doudna JA. Crystallization of RNA and RNA-protein complexes. Methods. 2004 Nov;34(3):408-14.

Ke A, Zhou K, Ding F, Cate JH, Doudna JA. A conformational switch controls hepatitis delta virus ribozyme catalysis. Nature. 2004 May 13;429(6988):201-5.

Ke A, Wolberger C. Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera. Protein Sci. 2003 Feb;12(2):306-12.

Ke A, Mathias JR, Vershon AK, Wolberger C. Structural and thermodynamic characterization of the DNA binding properties of a triple alanine mutant of MATalpha2. Structure. 2002 Jul;10(7):961-71.