Crystallography

A postdoctoral position in RNA Biology is available immediately for highly motivated individuals with a strong interest in integrated approaches to understanding the structure and function of RNA and RNA-protein complexes in the lab of Prof. Ailong Ke at Cornell University (http://sites.google.com/site/kelaboratory and http://mbg.cornell.edu/cals/mbg/faculty-staff/faculty/ke.cfm). The lab is interested in two main research areas: 1. structure and working mechanism of macromolecular machines in the eukaryotic RNA processing and degradation; 2. Structure and conformation dynamics of riboswitches in genetic regulation. Please check Nat Struct Mol Biol. 2008 Oct;15(10):1076-83, and Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16844-9 for representative publications. 

The position offers ideal opportunities for experienced crystallographers interested in continuing structural studies, but who would like to complement his or her expertise with other diverse tools for understanding the function and mechanism of RNA and proteins. The lab has extensive crystallographic resources, including regular access to synchrotron beamlines at the Cornell High Energy Synchrotron Source (CHESS) on campus.

Candidates should have (or expect) a Ph.D. or M.D. and should have experience in protein purification, crystallization, and structure determination.

Nucleic Acid Biochemistry

A postdoctoral position in nucleic acid biochemistry is available immediately for highly motivated individuals with strong interest in probing RNA structure-function relationship.  Candidates should have (or expect) a Ph.D. or M.D. and should have strong background in nucleic acid biochemistry such as chemical probing and crosslinking. Yeast genetics skills are a plus.