Katherine A. Brakora


Curriculum Vitae 

Education

 

            Ph.D. candidate in Integrative Biology, Fall 2004 - present

            University of California, Berkeley, CA
                 Advanced to candidacy April, 2006

            Major adviser: Kevin Padian, PhD

 

 B.S. in Biological Sciences, Magna Cum Laude, May 2002

            University of Notre Dame, Notre Dame, IN

            Cumulative GPA: 3.60           Upper Division GPA: 3.74

           

            Semester of Foreign Study, Fall 2000

            University of Notre Dame Australia, Fremantle, Western Australia

 

Selected Honors & Awards

o       Fulbright Fellow, Kenya, 2008-2009

o       NSF Graduate Research Fellowship, 2005-2008

o       Graduate Student Scholarship, UC Berkeley 2004-2005

o       Notre Dame Undergraduate Research Symposium 2nd place poster, 2001

o       Deans List 7 semesters

o       Notre Dame Scholar, 1998     

o       USAA scholarship, 1998-2001 ($1000/yr)

o       Nicole Zimeti scholarship, 1998 ($500)

o       Michael Umbarger scholarship, 1998 ($500)

o       Henley Dollars for Scholars scholarship, 1998 ($500)

 

Study & Research Funding

o      Beim Endowed Graduate Field Summer Research Fellowship, 2008 ($2100)

o       Integrative Biology Summer Research Grant, 2007 ($3000)

o       NSF Berkeley Travel grant, 2008  ($750) 

o       UCMP Graduate Research Award, 2007 ($2504)

o       Objectivist Summer Conference Scholarship, 2007

o       NSF GRF International travel grant, 2007 ($1000)

o      UCMP graduate student support grant, 2006 ($500)

o       GRAC Research fund award, 2006 ($200)

o       IB Dept. summer research block grant: $1000, 2006

o       GRAC Research Fund, summer fieldwork at Petrified Forest Nat’l Park, 2005 ($300)

o       UCMP graduate student support grant, 2005 ($400)

o       UCMP Welles Fund grant, 2005  ($1400)

o       Hotel Recovery grant for patient newsletter, 2003 ($2025)

o       MGH Making a Difference Program grant, 2002 ($2930)

o       Notre Dame Environmental Research Center, summer research fellow, 2000

 

Publications

Peer-Reviewed Articles

  

  Vaidya AP, Alterovitz G, Lee  H, Duan Z,  Foster R, Mahoney J, Brakora K, Roche MGrills G

           Decker J, Seiden MV. “Serum-based proteomic analysis of chemokines and  cytokines in

            ovarian cancer.” In preparation.


Duan Z, Foster R, Brakora KA, Yusuf RZ, Seiden MV. 2006. “GBP-1 overexpression is associated 

        with a paclitaxel resistant phenotype.” Cancer Chemother Pharmacol. 57(1):25-33. Epub 2005 

        Nov 5. [link]

 

Duan Z, Brakora KA, Seiden MV. 2004. “MM-TRAG (MGC4175), a novel intracellular 

        mitochondrial protein, is associated with the taxol- and doxorubicin-resistant phenotype in 

        human cancer cell lines.” Gene (Amsterdam). 340(1):53-59. [link]

 

Duan Z, Brakora KA, Seiden MV. 2004. “Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3

        expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian 

        cancer cells." Molecular Cancer Therapeutics. 3(7):833-838. [link]

 

Brakora KA, Lee H, Yusuf R, Sullivan L, Harris A, Colella T, Seiden MV. 2004. “Utility of 

        osteopontin as a biomarker in recurrent epithelial ovarian cancer.” Gynecologic Oncology.  

        93(2):361-365. [link]

 

Lin N, Brakora KA, Seiden MV. 2003. “BMS-247550 Bristol-Myers Squibb/GBF.” Current 

        Opinions in Investigational Drugs. 4(6):746-756. [link]


  

Conference Presentations and Posters

 

Brakora KA, Padian K. 2007. "Quantification and phylogenetic correlations of sexual 

        morphotypes in Bovidae (Mammalia)." Society of Vertebrate Paleontology Annual Mtg. [link]

 

Duan Z, Brakora KA, Foster R, Seiden MV. 2004. “Characterization of MM-TRAG, a 

        mitochondrial protein associated with MDR1 expression and the multidrug resistant 

        phenotype in vitro.American Association for Cancer Research Annual Mtg. Abs. 596.

 

Duan Z, Brakora KA, Foster R, Seiden MV. 2004. “Characterization of the GBP1 gene associated 

        with the multidrug resistant phenotype in vitro.” American Association for Cancer Research  

        Annual Mtg. Abs. 597.

 

Duan Z, Duan Y, Brakora KA, Lamendola DE, Yusuf RZ, Seiden MV. 2003. "cDNA array 

        technology identifies MGC 4175 and GBP-2 as candidate Taxol® resistance associated genes 

        (TRAGs)." Proceedings American Association for Cancer Research Annual Meeting. Abs. 1150.

 

   Brakora KA, Lee H, Yusuf R, Sullivan L, Harris A, Colella T, Seiden MV. 2003. "Utility of 

            osteopontin as a biomarker in recurrent epithelial ovarian cancer.” American Society for 

            Clinical Oncology Annual Meeting. Abs. 1862. 

 

    Duan Z, Brakora KA, Yusuf RZ, Seiden MV. 2003. "Inhibition of ABCB1 (MDR1) expression by     

            small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells.”  

            RNAi Boston Meeting.  

 

    Duan Z, Duan Y, Brakora KA, Lamendola DE, Yusuf RZ, Seiden MV. 2003. "cDNA array 

            technology identifies MGC 4175 and GBP-2 as paclitaxel resistance associated genes (TRAGs)."

             MGH Clinical Research Day.

 

    Hoagland, TM, Brakora KA, Olson KR. 2002. "Environmental salinity manipulation affects 

            fluid volume compartments and key indices of cardiovascular hemodynamics in the rainbow 

            trout." FASEB Journal. 16(5). A884.

 

    Brakora KA, Hoagland TM, Hambleton DC, Olson KR. 2001. “Blood

pressure and volume measurements in fresh and salt water-adapted rainbow trout.” University of NotreDame Undergraduate Research Symposium.

 

         

      Abstracts


     Vaidya AP, Brakora KA, Mahoney JC, Krasner C, Roche M, Lee H, Seiden MV. 2004. “An 

            unbiased systematic exploration of cytokines and chemokines identifies IL-6 as a potential 

            biomarker in ovarian cancer.” New England Association of Gynecologic Oncologists Annual 

            Meeting.

             

    Olson KR, Kinney DM, Brakora KA, Kingsley RE. 2002. “Transvascular fluid transport in the 

            rainbow trout.” FASEB Journal. 16(5). A884.  

 

Professional Societies

            American Society of Mammalogists, 2007-present

            Paleontological Society, 2007-present

            Society of Vertebrate Paleontology, 2003-present

            Society of Integrative and Comparative Biology, 2003-2004, 2007-present

            American Philosophical Association, 2007 - present

            Ayn Rand Society, APA Eastern Division, 2007 - present

            International Society for History Philosophy and Social Studies of Biology, 2006-present  

  

Research, Curatorial and Field Experience

   Graduate Student Researcher (visiting)

   Field Museum of Natural History, Chicago, IL (May, 2008)

   Museum of Comparative Zoology, Harvard University (April, 2008)

   California Academy of Sciences, San Francisco, CA  (winter 2007-2008)
        NFI/Transvaal Museum, Pretoria, South Africa  (May-June 2007)
        National Museums of Kenya, Nairobi, Kenya  (March-May, 2007)
        Etosha Ecological Institute,  Etosha National Park, Namibia  (February 2007)

   Florisbad Quaternary Research Center, Orange Free State, South Africa (Jan-Feb 2007)
        American Museum of Natural History, New York, NY  (June 2006)
       

   Graduate Student Researcher (resident)
        Museum of Paleontology, (2oo4- present)


   Curatorial Volunteer, Mammalogy
       
Museum of Vertebrate Zoology, spring 2008


    Fieldwork, Kenya, Spring 2008

    Development of tragelaphine antelopes; photography in Tsavo National Park, Saiwa Swamp 

         National Park, Hells Gate National Park, Lake Bogoria National Park, and Laikipia plateau.

 

    Fieldwork, Purgatoire River, CO, August 2005

    Jurassic sauropod trackways of the Purgatoire River, CO

 

    Paleontology InternPetrified Forest National Park, Petrified Forest, AZ 

    May - August 2005   

    Prospecting, excavation and preparation of Late Triassic terrestrial archosaurs, contributing to    

            the Park's paleontological resource inventory. Also relocating and documenting historic sites

            and expanding online educational resources in vertebrate paleontology. 

    Supervisor: William Parker, Park Paleontologist


    Research Assistant Boston College, Department of Biology, Chestnut Hill, MA

    September 2003 - August 2004  

    Vertebrate paleontology: Sauropod dinosaur trackways and body mass distributions.

    Adviser: David Krauss, PhD


    Research TechnicianMassachusetts General Hospital and Harvard Medical School, Boston, MA

    June 2002 - August 2004

    Basic and clinical cancer research: molecular mechanisms of carcinogenesis, paclitaxel
                resistance, and serological biomarkers in ovarian cancer. 

    Adviser: Michael Seiden, MD, PhD


    Research AssistantSouth Bend Center for Medical Education, South Bend, IN

    January - December 2001 

    Comparative cardiovascular physiology: transvascular filtration rates and hemodynamics of the
                rainbow trout, focusing on in vivo heart and vascular surgery. 

    Adviser: Kenneth Olson, PhD


    Undergrad Researcher, Univ. of Notre Dame Environmental Research Ctr,  Land O' Lakes, WI

    January - December 2000

    Aquatic biology and lake ecology: Species-specific predation by fish on Orconectes crayfishes in
                varying substrates. [link]

    Adviser: David Lodge, PhD        


 

Teaching Experience

           Graduate Student Instructor, University of California, Berkeley

           IB131L: Human Anatomy Lab -  Fall 2004, 2005, 2007, Summer 2007

           IB132L: Mammalian Physiology Lab -  Spring 2005

 

           Course Coordinator, University of California, Berkeley

           Shortcourse in geometric morphometrics, Summer 2006, 2007, 2008

           IB290: Technical writing for graduate students, Spring 2008

           IB290: Vertebrate skeletal morphology seminar co-organizer, Fall 2007

           Faculty Chalk Talk series, Fall 2007
                IB263:
Seminar in Paleontology, Fall 2006

  

           Undergraduate Research Assistant Supervisor, University of California, Berkeley

           Kim Khuc, Fall 2007 - present
                      Development of cranial sexual dimorphism in western springbok: A 2D geometric
                            morphometric study

           Noah Berger,  Spring 2008 - present

                   Paleobiological study of sauropods from a Jurassic track site in Colorado

           Carly Tribull,  Spring 2008 - present

                   Illustration of tragelaphine antelope skulls.

           

           Science Fair Mentor, Winter 2002-03
               
Mass. General Hospital/Howard Hughes Medical Institute/Timilty Middle School partnership

 

            Tutor, University of Notre Dame

            Art Tradiations II, Spring 2002

            Calculus I, Academic year 1999-2000

           

            Undergraduate Teaching Assistant, University of Notre Dame

            General Biology I, Fall 1999

 

Other Academic Activities

·         California Academy of Science Committee on History and Philosophy of Science, 2005-present 

·         Objectivist Club of Berkeley, co-founder and officer, 2005-present

·         Lawrence Hall of Science 3rd-4th grade book development project, consultant, Fall 2006

·         Graduate Assembly Departmental Delegate, Academic year 2005-2006