Gaming

Kotaku - Gaming news site that also caters a bit to Anime fans.
Game Politics - Political gaming news site.
Joystiq - A gaming news site similar to Kotaku.
The Escapist - Yet another gaming news site.  Home to Zero Punctuation with Yahtzee (can be slightly NSFW)

Anime

Anime New Network - One of the biggest, if not the biggest, anime news site.

Oddball

io9 - Part of Kotaku's network, io9 is dedicated to science fiction news, including movies and comics.
Bad Astronomy - Astronomer Phil Plait's blog about science, the stars, and some random science-y stuff that (probably) won't bore you.