Timeline & History
Measles, sneezles, and things that go mumps in the night

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Click here for an interactive timeline of Paramyxoviridae facts.

 

Fifth Century, B.C.E.

Hippocrates describes epidemic levels of orchitis and parotitis - early documentation of mumps.

 

10th Century

Arabic physicians initially identify measles as mild smallpox.

 

1600s

Sydenham describes measles as a distinct clinical entity.

 

1846

Danish physician Peter Panum recognizes measles' path of contagion through experiment in the Farow Islands.

 

1905

Hektoen persuades people to volunteer for measles transmission experiment.

 

1911

Anderson and Goldberger transmit measles to monkeys.

 

1918

Nicolle and Conseil demonstrate that inoculation of measles antibody-containing serum prevented/lessened clinical disease.

 

1932

Dawson first suggests that SSPE may be virally mediated.

 

1945

Measles virus propagated in embryonated chicken eggs.

 

1954

John Enders and Thomas Peebles isolate measles virus by growing it in post nasal tissue.

 

1963

The MMR vaccine is licensed and introduced to the American public.

 

1967

J.H. Connolly links SSPE to measles virus.

 

1984

PAHO initiates enhanced measles eradication strategies for the region of the Americas, targeting elimination of measles from the Western Hemisphere by 2000.

 

1994

Hendra virus first seen in racehorses and their trainers in Queensland, Australia.  The virus is later traced to fruit bat reservoir.

 

1997

Menangle virus discovered in Australian piggery; 2 of 250 workers there develop flu-like illness and rash.

 

1999

Nipah virus appears in malaysia; kills over 110 people, most of whom work with swine.

 

2000

Tioman virus discovered.

 

2001

The United States reports zero deaths due to measles.

 

2001

Human metapneumovirus isolated in the Netherlands; later mistaken as cause of SARS.