Overweight and obesity increase the risk for cardiovascular disease and adversely affect plasma lipids.
Each 1 kg increase in body weight has been observed to increase plasma triglycerides by 1.04% and decrease HDL-cholesterol by 0.83%. Conversely, decreases in body weight and body fat are associated with favorable changes in cardiovascular risk factors, including increased HDL-cholesterol concentrations and decreased total cholesterol, LDL-cholesterol and triglyceride concentrations. Every 1 kg decrease in body weight has been observed to decrease triglycerides by 0.77%-0.87% and increase HDL-cholesterol by about 1%. Weight management should be considered an important component of interventions intended to maximize lipid management and reduce risk of cardiovascular disease (Denke, 1999 [R]). |