PEER REVIEWED RESEARCH

1. Forman, H.J. and Feigelson, P.
Kinetic evidence indicating the absence during catalysis of an unbound ferroprotoporphyrin form of tryptophan oxygenase.
Biochemistry 10: 760‑763, 1971.

2. Brady, F.O., Forman, H.J. and Feigelson, P.
The role of superoxide and hydroperoxide in the reductive activation of tryptophan‑2,3‑dioxygenase.
J. Biol. Chem. 246: 7119‑7124, 1971.

3. Forman, H.J. and Feigelson, P.
The effects of allosteric interaction on the kinetics, spectra and tertiary structure of Pseudomonad tryptophan oxygenase.
J. Biol. Chem. 247: 256‑259, 1972.

4. Forman, H.J. and Fridovich, I.
Electrolytic univalent reduction of oxygen in aqueous solution demonstrated with superoxide dismutase.
Science 75: 339, 1972.

5. Brady, F.O., Monaco, M.E., Forman, H.J., Schutz, G. and Feigelson, P.
On the role of copper in activation and catalysis by tryptophan‑2,3‑dioxygenase.
J. Biol. Chem. 247: 7915‑7922, 1972.

6. Forman, H.J., Evans, H.J., Hill, R.L. and Fridovich, I.
Histidine at the active site of superoxide dismutase.
Biochemistry 12: 823‑827, 1973.

7. Forman, H.J. and Fridovich, I.
On the stability of bovine superoxide dismutase: the effects of metals.
J. Biol. Chem. 248: 2645‑2649, 1973.

8. Forman, H.J. and Fridovich, I.
Superoxide dismutase: a comparison of rate constants.
Arch. Biochem. Biophys. 158: 396‑400, 1973.

9. Forman, H.J., Waddell, R., Hamilton, P.B. and Grisolia, S.
Activation of carbamyl phosphate synthase by N‑acetyl‑L‑aspartate.
Biochem J. 143: 63‑66, 1974.

10. Forman, H.J. and Grisolia, S.
The effects of cyanate, carbamyl phosphate and growth on the glutamine dependent carbamyl phosphate synthetase from rat spleen and brain.
Physiol. Chem. & Physics 6: 213‑233, 1974.

11. Forman, H.J. and Kennedy, J.A.
Role of superoxide radical in mitochondrial dehydrogenase reactions.
Biochem. Biophys. Res. Commun. 60: 1044‑1050, 1974.

12. Forman, H.J. and Kennedy, J.
Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid.
J. Biol. Chem. 250: 4322‑4326, 1975.

13. Forman, H.J. and Kennedy, J.
Dihydroorotate dependent superoxide production in rat brain and liver; a function of the primary dehydrogenase.
Arch. Biochem. Biophys. 173: 219‑224, 1976.

14. Forman, H.J. and Kennedy, J.
Effects of chaotropic agents versus detergents on dihydroorotate dehydrogenase.
J. Biol. Chem. 252: 3379‑3387, 1977.

15. Forman, H.J. and Kennedy, J.
Purification and characterization of the superoxide producing primary dihydroorotate dehydrogenase from rat liver mitochondria.
Preparative Biochemistry 7: 345‑355, 1977.

16. Forman, H.J. and Kennedy, J.
Mammalian dihydroorotate dehydrogenase: Physical and catalytic properties of the primary enzyme.
Arch. Biochem. Biophys. 191: 23‑31, 1978.

17. Forman, H.J., York, J.L. and Fisher, A.B.
Mechanism for the potentiation of oxygen toxicity by disulfiram.
J. Pharmacol. Exp. Ther. 212: 452‑455, 1980.

18. Kravetz, G., Fisher, A.B. and Forman, H.J.
The oxygen‑adapted rat model: tolerance to oxygen at 1.5 and 2 ata.
Aviat. Space Environ. Med. 51: 775‑777, 1980.

19. Arad, I.D., Forman, H.J. and Fisher, A.B.
Ascorbate efflux from guinea pig and rat lungs: effect of starvation and O ₂ exposure.
J. Lab. Clin. Med. 96: 673‑681, 1980.

20. Forman, H.J., Nelson, J. and Fisher, A.B.
Rat alveolar macrophages require NADPH for superoxide production in the respiratory burst.
J. Biol. Chem. 255: 9879‑9883, 1980.

21. Forman, H.J. and Fisher, A.B.
Antioxidant enzymes in rat granular pneumocytes: constitutive levels and effect of hyperoxia.
Lab. Invest. 45: 1‑6, 1981.

22. Jowa, L.B., Fisher, A.B. and Forman, H.J.
Glucose‑dependent chemiluminescence by resting rat alveolar macrophages.
J. Reticuloendothelial Soc. 30: 99‑105, 1981.

23. Forman, H.J., Aldrich, T.K., Posner, M.A. and Fisher, A.B.
Differential paraquat accumulation and redox kinetics in rat lung cells.
J. Pharmacol. Exp. Ther. 221: 428‑433, 1982.

24. Forman, H.J., Williams, J.J., Nelson, J., Daniele, R.P. and Fisher, A.B.
Hyperoxia inhibits stimulated superoxide release by rat alveolar macrophages.
J. Appl. Physiol. 53: 685‑689, 1982.

25. Aldrich, T.K., Fisher, A.B. and Forman, H.J.
Paraquat inhibits mixed‑function oxidation by rat lung.
J. Appl. Physiol. 54: 1089‑1096, 1983.

26. Forman, H.J. and Nelson, J.
Effect of extracellular calcium on superoxide release by rat alveolar macrophages.
J. Appl. Physiol. 54: 1249‑1253, 1983.

27. Cameron, A.R., Nelson, J.,and Forman, H.J.
Depolarization and increased conductance precede superoxide release by concanavalin A stimulated rat alveolar macrophages.
Proc. Natl. Acad. Sci. USA 80: 3726‑3728, 1983.

28. Forman, H.J., Rotman, E.I. and Fisher, A.B.
The roles of selenium and sulfur‑containing amino acids in protection against oxygen toxicity.
Lab. Invest. 49: 148‑153, 1983.

29. Glass, M., Sutherland, M.W., Forman, H.J. and Fisher, A.B.
Selenium deficiency potentiates paraquat‑induced lipid peroxidation in isolated perfused rat lung.
J. Appl. Physiol. 59: 619‑622, 1985.

30. Sutherland, M.W., Glass, M., Nelson, J., Lyen, Y. and Forman, H.J.
Oxygen toxicity: loss of lung macrophage function without metabolite depletion.
J. Free Radic. Biol. Med. 1: 209‑214, 1985.

31. Sutherland, M.W., Nelson, J., Harrison, G. and Forman, H.J.
The effect of t‑butyl hydroperoxide on NADPH, glutathione and the respiratory burst of rat alveolar macrophages.
Arch. Biochem. Biophys. 243: 325‑331, 1985.

32. Forman, H.J., Nelson, J. and Harrison, G.
Hyperoxia alters the effect of Ca ²⁺ on rat alveolar macrophage superoxide production.
J. Appl. Physiol. 60: 1300‑1305, 1986.

33. Glass, M., Forman, H.J., Rotman, E.I., Clark, J.M., Pietra, G.G. and Fisher, A.B.
Cellular composition of lung lavage in oxygen toxicity.
J. Hyperbaric Med. 1: 107‑121, 1986.

34. Harrison, G. and Forman, H.J.
Progressive loss of the macrophage respiratory burst in oxygen toxicity.
J. Free Radic. Biol. Med. 2: 129‑134, 1986.

35. Dorio, R.J., Nelson, J. and Forman, H.J.
A dual role for calcium in the regulation of superoxide generation by stimulated rat alveolar macrophages.
Biochim. Biophys. Acta 928: 137-143, 1987.

36. Forman, H.J., Dorio, R.J. and Skelton, D.C.
Hydroperoxide induced damage to alveolar macrophage function and membrane integrity: alterations in intracellular free Ca ²⁺ and membrane potential.
Arch. Biochem. Biophys. 259: 457-465, 1987.

37. Dorio, R.J. and Forman, H.J.
Ethanol inhibition of signal transduction in superoxide production by rat alveolar macrophages: A proposed mechanism for ethanol-related pneumonia.
Ann. Clin. Lab. Sci. 18: 190-194, 1988.

38. Dorio, R.J., Hoek, J.B., Rubin, E. and Forman, H.J.
Ethanol modulation of rat alveolar macrophage superoxide production.
Biochem. Pharmacol. 37: 3528-3531, 1988.

39. Robison, T.W., Duncan, D.P. and Forman, H.J.
Kinetics of uptake and distribution of arachidonic acid by rat alveolar macrophages.
Prostaglandins 36: 443-461, 1988.

40. Loeb, G.A., Skelton, D.C., Coates, T.D. and Forman, H.J.
Role of the selenium-dependent glutathione peroxidase in antioxidant defense in rat alveolar macrophages.
Exp. Lung Res. 14: 921-936, 1988.

41. Ryer-Powder, J.E. and Forman, H.J.
Adhering lung macrophages produce superoxide demonstrated with Desferal-Mn(IV).
Free Radic. Biol. Med. 6: 513-518, 1989.

42. Loeb, G.A., Skelton, D.C. and Forman, H.J.
Dependence of mixed disulfide formation in alveolar macrophages upon production of oxidized glutathione: effect of selenium deficiency.
Biochem. Pharmacol. 38: 3119-3122, 1989.

43. Warburton, D., Buckley, S., Cosico, L. and Forman, H.J.
Sublethal oxidant injury inhibits signal transduction in rat type II pneumocytes.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 257: L217-L220, 1989.

44. Forman, H.J. and Kim, E.
Inhibition by linoleic acid hydroperoxide of rat alveolar macrophage superoxide production: effects upon mitochondrial and plasma membrane potentials.
Arch. Biochem. Biophys. 274: 443-452, 1989.

45. Robison, T.W., Duncan, D.P. and Forman, H.J.
Chemoattractant and leukotriene B ₄ production from rat alveolar macrophages exposed to nitrogen dioxide.
Am. J. Respir. Cell Mol. Biol. 3: 21-26, 1990.

46. Forman, H.J. and Skelton, D.C.
Protection of alveolar macrophages from hyperoxia by g‑glutamyl transpeptidase.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 259: L102-L107, 1990.

47. Robison, T.W., Duncan, D.P., Coates, T.D. and Forman, H.J.
Inhibition of production of LTB ₄ and chemoattractant from rat alveolar macrophages treated with t-butyl hydroperoxide is independent of ATP depletion.
Biochim. Biophys. Acta 1045: 9-16, 1990.

48. Robison, T.W., Sevanian, A. and Forman, H.J.
Inhibition of arachidonic acid release by nordihydroguaiaretic acid and its antioxidant action in rat alveolar macrophages and Chinese hamster lung fibroblasts.
Toxicol. Appl. Pharmacol. 105: 113-122, 1990.

49. Robison, T.W. and Forman, H.J.
t‑Butylhydroperoxide stimulates alveolar macrophage biosynthesis of cyclooxygenase products.
Prostaglandins 40: 13-28, 1990.
50. Walther, F.J., Wade, A.B., Warburton, D. and Forman, H.J.
Ontogeny of antioxidant enzymes in the fetal lamb lung.
Exp. Lung Res. 17: 39-45, 1991.

51. Walther, F.J., Wade, A.B., Warburton, D. and Forman, H.J.
Augmentation of superoxide dismutase activity in alveolar type II cells.
Am. J. Respir. Cell Mol. Biol. 4: 364-368, 1991.

52. Heisterkamp, N., Rajpert-De Meyts, E., Uribe, L., Forman, H.J. and Groffen, J.
Identification of a novel human g‑glutamyl cleaving enzyme related to g‑glutamyl transpeptidase.
Proc. Natl. Acad. Sci. USA 88: 6303-6307, 1991.

53. Chang, M., Shi, M. and Forman, H.J.
Exogenous glutathione protects endothelial cells from menadione toxicity.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 262: L637-643, 1992.

54. Rajpert-De Meyts, E., Shi, M., Chang, M., Robison,T.W., Groffen, J., Heisterkamp, N. and Forman, H.J.
Transfection with g‑glutamyl transpeptidase enhances recovery from glutathione depletion using extracellular glutathione.
Toxicol. Appl. Pharmacol. 114: 56-62, 1992.

55. Livingston, F.R., Lui, E., Loeb, G. and Forman, H.J.
Sublethal oxidant stress induces a reversible increase in intracellular calcium dependent on NAD(P)H oxidation in rat alveolar macrophages.
Arch. Biochem. Biophys. 299: 83-91, 1992.

56. Robison, T.W. and Forman, H.J.
Dual effects of nitrogen dioxide upon rat alveolar macrophage arachidonate metabolism.
Exp. Lung Res.19: 21-36, 1993.

57. Robison, T.W., Murphy, J.K., Beyer, L.L., Richters, A. and Forman, H.J.
Depression of stimulated arachidonate metabolism and superoxide production in rat alveolar macrophages following in vivo exposure to 0.5 ppm NO₂.
J. Toxicol. Environ. Health 38: 273-292, 1993.

58. Murphy, J.K. and Forman, H.J.
Effects of sodium and pH upon the respiratory burst and pH regulation of rat alveolar macrophages.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 264: L523-532, 1993.

59. Shi, M., Gozal, E., Choy, H.A. and Forman, H.J.
Extracellular glutathione and g-glutamyl transpeptidase prevent H₂O₂-induced injury by 2,3-dimethoxy-1,4-naphthoquinone.
Free Radic. Biol. Med. 15: 57-67, 1993.

60. Murphy, J.K., Livingston, F.R., Gozal, E., Torres, M. and Forman, H.J.
Stimulation of the rat alveolar macrophage respiratory burst by extracellular adenine nucleotides.
Am. J. Respir. Cell Mol. Biol. 9: 505-510, 1993.

61. Shi, M., Iwamoto, T. and Forman, H.J.
g‑Glutamylcysteine synthetase and glutathione increase in quinone-induced oxidative stress in bovine pulmonary artery endothelial cells.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 267: L414-L421, 1994.

62. Shi, M.M., Kugelman, A., Iwamoto, T., Tian, L. and Forman, H.J.
Quinone-induced oxidative stress elevates glutathione and induces g‑glutamylcysteine synthetase activity in rat lung epithelial L2 cells.
J. Biol. Chem. 269: 26512-26517, 1994.

63. Kugelman, A., Choy, H.A., Liu, R.M., Shi, M., Gozal, E. and Forman, H.J.
g-Glutamyl transpeptidase is increased by oxidative stress in rat alveolar L-2 epithelial cells.
Am. J. Respir. Cell Mol. Biol. 11: 586-592, 1994.
doi:10.1016/j.freeradbiomed.2005.11.005

64. Murphy, J.K., Livingston, F.R., Duncan, D.P., Hoyal, C. and Forman, H.J.
Modulation of the alveolar macrophage respiratory burst by hydroperoxides.
Free Radic. Biol. Med. 18: 37-45, 1995.

65. Thomas, M.J., Robison, T.W., Samuel, M. and Forman, H.J.
Detecting and identifying volatile aldehydes as dinitrophenylhydrazones using gas chromatography mass spectrometry.
Free Radic. Biol. Med. 18: 553-557, 1995.

66. Robison, T.W., Zhou, H. and Forman, H.J.
Modulation of ADP-stimulated inositol phosphate metabolism in rat alveolar macrophages by oxidative stress.
Arch. Biochem. Biophys. 318: 215-220, 1995.

67. Robison, T.W., Samuel, M., Forman, H.J. and Thomas, M.J.
Release of aldehydes from rat alveolar macrophages exposed in vitro to low concentrations of nitrogen dioxide.
Biochim. Biophys. Acta 1256: 334-340, 1995.

68. Liu, R.-M., Hu, H., Robison, T.W. and Forman, H.J.
Differential enhancement of g-glutamyl transpeptidase and g‑glutamylcysteine synthetase by tert-butylhydroquinone in rat lung epithelial L2 cells.
Am. J. Respir. Cell Mol. Biol. 14: 186-191, 1996.

69. Liu, R.-M., Hu, H., Robison, T.W. and Forman, H.J.
Increased g‑glutamylcysteine synthetase and g‑glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity.
Am. J. Respir. Cell Mol. Biol. 14: 192-197, 1996.

70. Hoyal, C.R., Gozal, E., Zhou, H., Foldenauer, K. and Forman, H.J.
Modulation of the rat alveolar macrophage respiratory burst by hydroperoxides is calcium dependent.
Arch. Biochem. Biophys. 326: 166-171, 1996.

71. Kaul, N. and Forman, H.J.
Activation of NF‑ kB by the respiratory burst of macrophages.
Free Radic. Biol. Med. 21: 401-405, 1996.

72. Hoyal, C.R., Thomas, A.P. and Forman, H.J.
Hydroperoxide-induced increases in intracellular calcium due to annexin VI translocation and inactivation of plasma membrane Ca ²⁺-ATPase.
J. Biol. Chem. 271: 29205-29210, 1996.

Qiu, X., Forman, H.J., Schönthal, A.H. and Cadenas, E.
Induction of p21 mediated by reactive oxygen species during the metabolism of aziridinylbenzoquinones by HCT116 cells.
J. Biol. Chem. 271: 31915-31921, 1996.

Choi, J., Liu, R.-M. and Forman, H.J.
Adaptation to oxidative stress: Quinone-mediated protection of signaling in rat lung epithelial L2 cells.
Biochem. Pharmacol. 53: 987-993, 1997.

75. Tian, L., Shi, M.M. and Forman, H.J.
Increased transcription of the regulatory subunit of g‑glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion.
Arch. Biochem. Biophys. 342: 126-133, 1997.

76. Zhou, H., Duncan, R.F., Robison, T.W. and Forman, H.J.
Ca ²⁺-dependent p47^phox translocation in hydroperoxide modulation of the alveolar macrophage respiratory burst.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 273: L1042-L1047, 1997.

77. Anderson, C.P., Tsai, J., Park, C.K., Tian, L., Liu, R.M., Forman, H.J. and Reynolds, C.P.
Buthionine sulfoximine alone and in combination with melphalan is highly cytotoxic for human neuroblastoma cells.
Eur. J. Cancer 33: 2016-2019, 1997.

78. Suzuki, Y.J., Forman, H.J. and Sevanian, A.
Oxidants as stimulators of signal transduction.
Free Radic. Biol. Med. 22: 269-285, 1997.

79. Kaul, N., Choi, J. and Forman, H.J.
Transmembrane redox signaling activates NF‑ kB in macrophages.
Free Radic. Biol. Med. 24: 202-207, 1998.

80. Kaul, N., Gopalakrishna, R., Gundimeda, U., Choi, J. and Forman, H.J.
Role of protein kinase C in basal and hydrogen peroxide-stimulated NF‑kB activation in the murine macrophage J774A.1 cell line.
Arch. Biochem. Biophys. 350: 79-86, 1998.

81. Liu, R.-M., Shi, M.M., Giulivi, C. and Forman, H.J.
Quinones increase g-glutamyl transpeptidase expression by multiple mechanisms in rat lung epithelial cells.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 274: L330-L336, 1998.

82. Hoyal, C.R., Girón-Calle, J. and Forman, H.J.
The alveolar macrophage as a model of calcium signaling in oxidative stress.
J. Toxicol. Environ. Health B Crit Rev. 1: 117-134, 1998.

83. Moellering, D., McAndrew, J., Patel, R.P., Cornwell, T., Lincoln, T., Cao, X., Messina, J.L., Forman, H.J., Jo, H. and Darley-Usmar, V.M.
Nitric oxide dependent induction of glutathione synthesis through increased expression of g‑glutamylcysteine synthetase.
Arch. Biochem. Biophys. 358: 74-82, 1998.

84. Forman, H.J., Zhou, H., Gozal, E. and Torres, M.
Modulation of the alveolar macrophage superoxide production by protein phosphorylation.
Environ. Health Perspect. 106 S5:1185-1190, 1998.

85. Liu, R.-M., Gao, L., Choi, J. and Forman, H.J.
g‑Glutamylcysteine synthetase: mRNA stabilization and independent subunit transcription by 4-hydroxy-2-nonenal.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 275: L861-L869, 1998.

86. Anderson, C.P., Tsai, J.M., Meek, W.E., Liu, R.-M., Tang, Y., Forman, H.J. and Reynolds, C.P.
Depletion of glutathione by buthionine sulfoximine alone is cytotoxic for human neuroblastoma cell lines via apoptosis.
Exp. Cell Res. 246:183-192, 1999.

87. Moellering, D., Mc Andrew, J., Patel, R.P., Forman, H.J., Mulcahy, R.T., Jo, H. and Darley-Usmar, V.M.
The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for g-glutamylcysteine synthetase and g-glutamyl transpeptidase.
FEBS Lett. 448: 292-296, 1999.

88. Gao, L. Kim, K.J., Yankaskas, J.R. and Forman, H.J.
Abnormal glutathione transport in cystic fibrosis airway epithelia.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 277: L113-118, 1999.

89. Torres, M. and Forman, H.J.
Activation of several MAP kinases upon stimulation of rat alveolar macrophages: role of the NADPH oxidase.
Arch. Biochem. Biophys. 366: 231-239, 1999.

90. Choi, J., Liu, R.-M., Kundu, R.K., Sangiorgi, F., Wu, W., Maxson, R. and Forman, H.J.
Molecular mechanism of decreased glutathione content in HIV type 1 Tat-transgenic mice.
J. Biol. Chem. 275: 3693-3698, 2000.

91. Choi, J., Opalenik, S.R., Wu, W., Thompson, J.A. and Forman, H.J.
Modulation of GSH synthetic enzymes by acidic fibroblast growth factor.
Arch. Biochem. Biophys. 375: 201-209, 2000.

92. Lee, Y.J., Galoforo, S.S., Sim, J.E., Ridnour, L.A., Choi, J., Forman, H.J., Corry, P.M. and Spitz, D.R.
Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in a human breast carcinoma cell line.
Free Radic. Biol. Med. 28: 575-584, 2000.

93. Jha, N. Jurma, O. Lalli, G. Liu, Y., Pettus, E.H., Greenamyre, J.T., Liu, R.-M., Forman, H.J. and Andersen, J.K.
Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity: implications for Parkinson’s disease.
J. Biol. Chem. 275: 26096-26101, 2000.

94. Girón-Calle, J. and Forman, H.J.
Phospholipase D and priming of the respiratory burst by H₂O₂ in NR8383 alveolar macrophages.
Am. J. Respir. Cell Mol. Biol. 23: 748-754, 2000.

95. Liu, R.-M., Borok, Z. and Forman, H.J.
4-Hydroxy-2-nonenal increases g-glutamylcysteine synthetase gene expression in alveolar epithelial type II cells.
Am. J. Respir. Cell Mol. Biol. 24: 499-505, 2001.

96. Gao, L., Broughman, J.R., Iwamoto, T., Tomich, J.M., Venglarik, C.J. and Forman, H.J.
Synthetic chloride channel restores glutathione secretion in cystic fibrosis airway epithelia.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 281: L24-L30, 2001.

97. Gozal, E., Forman, H.J., and Torres, M.
ADP stimulates the respiratory burst without activation of ERK and AKT.
in rat alveolar macrophages.
Free Radic. Biol. Med. 31: 679-687, 2001.

98. Gao, L., Yankaskas, J.R., Fuller, C.M., Sorscher, E.J., Matalon, S. Forman, H.J. and Venglarik, C.J.
Chlorzoxazone or 1-EBIO increases Na ⁺ absorption across cystic fibrosis airway epithelial cells.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 281: L1123-L1129, 2001.

99. Levonen, A.-L., Dickinson, D.A., Mulcahy, R.T., Forman, H.J., and Darley-Usmar, V.M.
Biphasic effects of 15-deoxy-D^12,14 -prostaglandin J₂ on glutathione induction and apoptosis in human endothelial cells.
Arterioscler. Thromb. Vasc. Biol. 21: 1846-51, 2001.

100. Girón-Calle, J., Srivatsa, K., and Forman, H.J.
Priming of the alveolar macrophage respiratory burst by H ₂O₂ is prevented by the phosphatidylcholine-specific phospholipase C inhibitor, tricyclodecan-9-yl-xanthate (D609).
J. Pharmacol. Exp. Ther. 301: 87-94, 2002.

101. Moellering, D., Go, Y.-M., Levonen, A.-L., Patel, R.P., Dickinson, D.A., Forman, H.J., and Darley-Usmar, V.M. Induction of glutathione synthesis by oxidized low density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: protection from oxidant-mediated cytotoxicity.
Biochem. J. 362: 51-59, 2002.

102. West, J.A.A., Williams, K.J., Toskala E., Nishio, S., Fleschner, C., Forman, H.J., Buckpitt, A.R., and Plopper, C.G.
Induction of tolerance to naphthalene in Clara cells is dependent on a stable phenotypic adaptation favoring maintenance of the GSH pool.
Am. J. Pathol. 160: 1115-1127, 2002.

103. Iles, K.E., Dickinson, D.A., Watanabe, N., Iwamoto, T. and Forman, H.J.
AP-1 activation through endogenous H₂O₂ generation by alveolar macrophages.
Free Radic. Biol. Med. 32: 1304-1313, 2002.

104. Forman, H.J., Torres, M. and Fukuto, J.
Redox signaling.
Mol. Cell. Biochem. 234: 49-62, 2002.
105. Dickinson, D.A. and Forman, H.J.
Cellular glutathione and thiols metabolism.
Biochem. Pharmacol. 64: 1021-1028, 2002.

106. Watanabe, N., Dickinson, D.A., Krzywanski, D.M., Iles, K.E., Zhang, H., Venglarik, C.J. and Forman, H.J.
A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 283: L726-736, 2002.

107. Dickinson, D.A., Iles, K.E., Watanabe, N., Iwamoto, T., Zhang, H., Krzywanski, D.M. and Forman, H.J.
4-hydroxynonenal induces glutamate cysteine ligase through JNK in HBE1 cells.
Free Radic. Biol. Med. 33: 974-987, 2002.

108. Watanabe, N., Iwamoto, T., Dickinson, D.A., Iles, K.E., and Forman, H.J.
Mitochondrial caspase activation in absence of protein synthesis does not require JNK.
Arch. Biochem. Biophys. 405: 231-240, 2002.

109. Iles, K.E. and Forman, H.J.
Macrophage signaling and the respiratory burst.
Immunol. Res. 26: 95-105, 2002.

110. Forman, H.J. and Torres, M.
Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling.
Am. J. Resp. Crit. Care Med. 166: S4-S8, 2002.

111. Dickinson, D.A. and Forman, H.J.
Glutathione in defense and signaling: lessons from a small thiol.
Ann. N.Y. Acad. Sci. 973: 488-504, 2002.

112. Torres, M. and Forman, H.J.
Vanadate inhibition of protein tyrosine phosphatases mimics hydrogen peroxide in the activation of the ERK pathway in alveolar macrophages.
Ann. N.Y. Acad. Sci. 973: 345-348, 2002.

113. Dickinson, D.A., Iles, K.E., Zhang, H., Blank, V. and Forman, H.J.
Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression.
Faseb J. (January 2, 2003) 10.1096/fj.02-0566fje (Full text - online).
Faseb J. 17: 473-475, 2003 (Print version summary).

114. Watanabe, N. and Forman, H.J.
Autooxidation of extracellular hydroquinones is a causative event for the cytotoxicity of menadione and DMNQ in A549-S cells.
Arch. Biochem. Biophys. 411: 145-157, 2003.

115. Watanabe, N., Iwamoto, T., Bowen, K.D., Dickinson, D.A., Torres, M. and Forman, H.J.
Bio-effectiveness of Tat-catalase conjugate: A potential tool for the identification of H ₂O₂-dependent cellular signal transduction pathways.
Biochem. Biophys. Res. Commun. 303: 287-293, 2003.

116. Dickinson, D.A., Moellering, D.R., Iles, K.E., Patel, R.P., Levonen, A.-L. Wigley, A., Darley-Usmar, V.M. and Forman, H.J.
Cytoprotection against oxidative stress and the regulation of glutathione synthesis.
Biol. Chem. 384: 527-537, 2003.

117. West, J.A.A., Van Winkle, L.S., Morin, D., Fleschner, C.A., Forman, H.J., Buckpitt, A.R., and Plopper, C.G.
Repeated inhalation exposures of the bioactivated cytotoxicant naphthalene produce airway specific clara cell tolerance in mice.
Toxicological Sciences 75: 161-168, 2003

118. Thome, U., Lazrak, A., Chen, L., Kirk, M.C., Thomas, M.J., Forman, H.J. and Matalon, S.
Novel SIN-1 reactive intermediates modulate chloride secretion across murine airway cells.
Free Radic. Biol. Med. 35: 662-675, 2003.

119. Venglarik, C.J., Girón-Calle, J., Wigley, A.F., Malle, E., Watanabe, N. Forman, H.J.
Hypochlorous acid alters bronchial epithelial cell membrane properties and prevention by extracellular glutathione.
J. Appl. Physiol. 95: 2444-2452, 2003.
 
120. Liu, R.-M., Liu, Y., Forman, H.J., Olman, M., and Tarpey, M.M.
Glutathione regulates transforming growth factor-b-stimulated colagen production in fibroblasts.
Am. J. Physiol.: Lung Cell. Molec. Physiol. 286: L121-L128, 2004.
121. Krzywanski, D.M., Dickinson, D.A., Iles, K.E., Wigley, A.F., Franklin, C.C., Liu, R.-M., Kavanagh, T.J. and Forman, H.J.
Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.
Arch. Biochem. Biophys. 423: 116-25, 2004.

122. Forman, H.J., Fukuto, J.M., and Torres, M.
Redox signaling - thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers.
Am. J. Physiol: Cell Physiol. 287: C246-C256, 2004.

123. Mirecki, A., Fitzmaurice, P., Ang, L. Kalasinsky, K.S., Peretti, F.J., Aiken, S.S., Wickham, D.J., Sherwin, A. Nobrega, J.N. Forman, H.J., and Kish, S.J.
Brain antioxidant systems in human methamphetamine users.
J. Neurochem. 89: 1396-1408, 2004.

124. Dickinson, D.A., Levonen, A.-L., Moellering, D.R., Arnold, E.K., Zhang, H., Darley-Usmar, V.M., Forman, H.J.
Human glutamate cysteine ligase gene regulation through the electrophile response element
Free Radic. Biol. Med. 37: 1152-1159, 2004.

125. Zhang, H., Dickinson, D.A., Liu, R.-M., and Forman, H.J.
4-Hydroxynonenal increases gamma-glutamyl transpeptidase gene expression through mitogen activated protein kinases pathways.
Free Radic. Biol. Med. 38: 463-471, 2005.

126. Rahman, I., Biswas, S.K., Jimenez, L.A., Torres, M., Forman, H.J.
Glutathione, stress responses, and redox signaling in lung inflammation.
Antioxid. Redox Signal. 7: 42-58, 2005.

127. Ridnour, L.A., Sim, J.E., Choi, J., Dickinson, D.A., Forman, H.J., Ahmad, I.M., Coleman, M.C., Hunt, C.R., Goswami, P.C., and Spitz, D.R.
Nitric oxide-induced resistance to hydrogen peroxide stress is a glutamate cysteine ligase activity-dependent process.
Free Radic. Biol. Med. 38: 1361-1371, 2005.

128. lles, K.E., Dickinson, D.A., Wigley, A,F., Welty, N.E., Blank, V. and Forman, H.J.
HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells.
Free Radic. Biol. Med. 39: 355-364, 2005.

129. Martín, M.E., Muñoz, F.M., Dickinson, D.A., Forman, H.J., del Río, R.M., Salinas, M. and Fando, J.L.
Protective effect of L-trans-pyrrolidine-2,4-dicarboxilic acid preload against cell death by oxygen/glucose deprivation in differentiated PC12 cells.
J. Neuroscience Res. 82: 93-102, 2005

130. Zhang, H., Liu, H., Iles, K.E., Liu, R.-M., Postlethwait, E.M., Laperche, Y., and Forman, H.J.
4-Hydroxynonenal induces rat g--glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling.
Am. J. Respir. Cell Mol. Biol. 34: 174-181, 2006. doi: 10.1165/rcmb.2005-0280OC

131. Zhang, H., Liu, H., Dickinson, D.A., Liu, R.-M., Postlethwait, E.M., Laperche, Y., and Forman, H.J.
g-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells.
Free Radic. Biol. Med. 40: 1281-1292, 2006.
doi: 10.1016/j.freeradbiomed.2005.11.005.

132. Chinta, S.J., Kumar, J.M., Zhang, H., Forman, H.J., Andersen, J.K.
Up-regulation of g-glutamyl transpeptidase (GGT) activity following GSH depletion has a compensatory rather than inhibitory effect on mitochondrial complex I activity: implications for Parkinson's disease.
Free Radic. Biol. Med. 40: 1557-1563, 2006. doi:10.1016/j.freeradbiomed.2005.12.023

133.  Rinna, A. Torres, M., and Forman, H.J.
Stimulation of the alveolar macrophage respiratory burst by ADP causes selective glutathionylation of protein tyrosine phosphatase 1B.
Free Radic. Biol. Med. 41: 86-91, 2006. doi: 10.1016/j.freeradbiomed.2006.03.010

134. Liu, H., Zhang, H., Iles, K.E., Rinna, A. Merrill, G., Yodoi, J., Torres, M., and Forman, H.J.
The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages.
Free Radic. Res. 40: 865-874, 2006. doi: 10.1080/10715760600758514

135. Choi, J., Forman, H.J., Ou, J., Lai, M.M.C., Seronello, S., Nandipati, A.
Redox modulation of the hepatitis C virus replication complex is calcium dependent.
Free Radic. Biol. Med. 41: 1488–1498, 2006. doi:10.1016/j.freeradbiomed.2006.08.008

136. Cantin, A.M., White, T.B., Cross, C.E., Forman, H.J., Sokol, R.J., and Borowitz, D.
Antioxidants in cystic fibrosis.
Free Radic. Biol. Med. 42: 15-31, 2007. doi: 10.1016/j.freeradbiomed.2006.09.022

137. Zhang, H., Court, N., and Forman, H.J.
Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells.
Redox Reports 12: 101-106, 2007. doi: 10.1179/135100007X162266

138. Liu, H., Zhang, H. and Forman, H.J.
Silica induces macrophage cytokines through phosphatidylcholine-specific
phospholipase C with H ₂O₂.
Am. J. Respir. Cell Mol. Biol. 36: 594-599 2007. doi: 10.1165/rcmb.2006-0297OC
 
139. Cruz, C.M., Rinna, A., Forman, H.J., Ventura, A.L.M., Persechini, P.M. and Ojcius, D.M.
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages.
J. Biol. Chem. 282: 2871–2879, 2007. doi: 10.1074/jbc.M608083200
           
140. Forman, H.J.
Use and abuse of exogenous H ₂O₂ in studies of signal transduction.
Free Radic. Biol. Med. 42: 926–932, 2007. doi: 10.1016/j.freeradbiomed.2007.01.011

141. Zhang, H. and Forman, H.J.
Acrolein induces heme oxygenase-1 through PKCd and PI3K in human bronchial epithelial cells.
Am. J. Respir. Cell Molec. Biol. 38: 483-490, 2008. doi:10.1165/rcmb.2007-0260OC

142. Rinna, A. and Forman, H.J.
SHP-1 inhibition by 4-hydroxynonenal activates Jun N-terminal kinase and glutamate cysteine ligase.
Am. J. Respir. Cell Molec. 39: 97-104, 2008. doi:10.1165/rcmb.2007-0371OC

143. Ding, Y., Choi, K.J., Kim, J.H., Han, X., Piao, Y., Jeong, J.-H., Choe, W., Kang, I., Ha, J., Forman, H.J., Lee, J., Yoon, K.-S., Kim, S.S.
Endogenous H₂O₂ regulates GSH redox via Nrf2 downstream of PI 3-kinase during muscle differentiation.
Am. J. Pathol. 172: 1529-1541, 2008. doi:10.2353/ajpath.2008.070429

144. Janssen-Heininger, Y.M.W., Mossman, B.T., Heintz, N.H., Forman, H.J., Kalyanaraman, B., Finkel, T., Stamler, J.S., Rhee, S.G., and Van der Vliet, A.
Redox-based regulation of signal transduction: principles, pitfalls, and promises.
Free Radic. Biol. Med. 45: 1-17, 2008. doi:10.1016/j.freeradbiomed.2008.03.011

145. Bindoli A., Fukuto J.M., Forman H.J.
Thiol chemistry in peroxidase catalysis and redox signaling.
Antioxid. Redox Signal. 10: 1-16, 2008 doi:10.1089/ars.2008.2063

146. Sunagawa, S., Choi, J., Forman, H.J., and Medina, M.
Hyperthermic stress-induced increase in the expression of glutamate-cysteine ligase and glutathione levels in the symbiotic sea anemone Aiptasia pallida.
Comp. Biochem. Physiol. Part B 151: 133-138 2008 doi:10.1016/j.cbpb.2008.06.007 

147. Forman, H.J., Fukuto, J.M., Miller, T., Zhang, H., Rinna, A., and Levy, S.
The chemistry of cell signaling by reactive oxygen and nitrogen species and  4-hydroxynonenal.
Arch. Biochem. Biophys. 477: 183-195, 2008 doi:10.1016/j.abb.2008.06.011

148. Forman, H.J., Zhang, H. and Rinna, A.
Glutathione: Overview of its protective roles, measurement, and biosynthesis.
Molec. Aspects Med. 30: 1-12, 2009  doi:10.1016/j.mam.2008.08.006

149. Chen, J.-L., Lin, H.H. Kim, K.J., Lin, A., Forman, H.J. and Ann, D.K.
Novel roles for protein kinase Cδ-dependent signaling pathways in acute hypoxic stress-induced autophagy.
J. Biol. Chem. 283: 34432-34444, 2008 doi:10.1074/jbc.M804239200

150. Franklin, C.C., Backos, D.S., Mohar, I., White, C.C., Forman, H.J. and Kavanagh, T.J.
Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase.
Molec. Aspects Med. 30: 86-98, 2009 doi:10.1016/j.mam.2008.08.009 

151. Zhang, H., Shih, A., Rinna, A., and Forman, H.J.
Resveratrol and 4-hydroxynonenal act in concert to increase glutamate cysteine ligase expression and glutathione in human bronchial epithelial cells.
Arch. Biochem. Biophys. 481: 110-115, 2009 doi:10.1016/j.abb.2008.10.020

152. Zhang, H. and Forman, H.J.
Signaling pathways involved in phase II gene induction by α, β-unsaturated aldehydes.
Toxicol. Industrial Health 25: 269-278, 2009

153. Mahaffey, C.M., Zhang, H., Rinna, A., Holland, W., Mack, P.C., and Forman, H.J.
Multidrug resistant protein-three gene regulation by the transcription factor Nrf2 in human bronchial epithelial and non-small cell lung carcinoma.
Free Radic. Biol. Med. 46: 1650-1657, 2009 doi:10.1016/j.freeradbiomed.2009.03.023

154. Soñanez-Organis, J.G., Peregrino-Uriarte, A.B., Gómez-Jiménez, S., López-Zavala, A., Forman, H.J., and Yepiz-Plascencia, G.
Molecular characterization of hypoxia inducible factor-1 (HIF-1) from the white shrimp Litopenaeus vannamei and tissue-specific expression under hypoxia.
Comp. Biochem. Physiol. Part C 150: 395-405, 2009 doi: 10.1016/j.cbpc.2009.06.005

155. Levy, S., Jaiswal, A., and Forman, H.J.
The role of c-Jun phosphorylation in EpRE activation of Phase II genes.
Free Radic. Biol. Med. (in press) doi:10.1016/j.freeradbiomed.2009.07.036

156. Zhang, H. and Forman, H.J.
Redox regulation of gamma-glutamyl transpeptidase.
Am. J. Respir. Cell Molec. (in press) doi:10.1165/rcmb.2009-0169TR

BOOKS
1. Forman, H.J. and Cadenas, E., editors
Oxidative Stress and Signal Transduction
Chapman Hall, New York, 475 pp., 1997

2. Forman, H.J., Fukuto, J., and Torres, M., editors
Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles
Kluwer Academic Publishers, Dordrecht, 436 pp., 2003

BOOK

CHAPTERS, NON-PEER REVIEWED JOURNALS, CONFERENCE PROCEEDINGS
 
1. Fisher, A.B., Bassett, D.J.P. and Forman, H.J.
Oxygen toxicity of the lung: Biochemical aspects.
In: Pulmonary Edema: A.P. Fishman and S. Geiger, editors, Am. Physiol. Soc., 1978, pp 207-216.

2. Forman, H.J.
The role of ubisemiquinone in superoxide production by dihydroorotate dehydrogenase.
In: The Significance of Superoxide and Superoxide Dismutase. Vol. I, J.V. Bannister and H.A.O. Hill, editors, Elsevier, 1980, pp 76‑83.

3. Forman, H.J. and Fisher, A.B.
Anti-oxidant defenses.
In: Oxygen and Living Processes: D.L. Gilbert, editor, Springer-Verlag, 1981, pp 237-249.

4. Forman, H.J. and Boveris, A.
Superoxide radical and hydrogen peroxide in mitochondria.
In: Free Radicals in Biology: Vol. V, W.A. Pryor, editor, Academic Press, 1982, pp 65-90.

5. Forman, H.J., Cameron, A.R. and Nelson, J.
Alteration of membrane properties in the activation of alveolar macrophage superoxide release.
In: Oxy Radicals and Their Scavenging Systems. Vol. II. Cellular. R. Greenwald and G. Cohen, editors, Elsevier, 1983, pp 74‑80.

6. Forman, H.J. and Fisher, A.B.
Role of glutathione peroxidase in tolerance and adaptation to hyperoxia.
In: Oxygen Radicals in Chemistry and Biology. W. Bors, M. Saran, and D. Tait, editors Walter de Gruyter, 1984, pp. 699‑ 705.

7. Fisher, A.B. and Forman, H.J.
Natural defense mechanisms against oxygen and its derivatives.
In: Workshop on oxygen: In‑depth study of pathophysiology. Oak Ridge National Laboratories, 1984, pp. 433‑457.

8. Fisher, A.B., Forman, H.J. and Glass, M.
Mechanisms of Pulmonary Oxygen Toxicity.
Lung 162: 255‑259, 1984.

9. Fisher, A.B. and Forman, H.J.
Oxygen utilization and toxicity.
In: Handbook of Physiology, Section 3: The Respiratory System, Vol. I, Circulation and Nonrespiratory Functions: A.P. Fishman and A.B. Fisher, editors, Am. Physiol. Soc., 1985, pp 231-254.

10. Forman, H.J. and Fisher, A.B.
Antioxidant enzymes in the lung.
In: Handbook of Methods in Oxy Radical Research: R.A. Greenwald, editor, CRC Press, 1985, pp 359-364.

11. Forman, H.J.
The effects of oxidant stress on pulmonary metabolic functions.
In: Mechanisms of Lung Injury. T.P. Stein and G. Weinbaum, editors, George F. Stickley Co., 1985, pp. 141-153.

12. Forman, H.J. and Thomas, M.J.
Oxidant production and bactericidal activity of phagocytes.
In: Annual Reviews in Physiology: 1986, pp 669-680.

13. Forman, H.J., Nelson, J. and Harrison, G. .
Hyperoxia causes loss of the extracellular calcium dependence of the rat alveolar macrophage respiratory burst. .
In: Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine. G. Rotilio, editor, Elsevier, 1986, pp. 413‑41.

14. Dorio, R.J., Hoek, J.B., Forman, H.J. and Rubin, E.
The effect of ethanol on superoxide production in alveolar macrophages.
Ann. N.Y. Acad. Sci. 492: 324-326, 1986.

15. Coburn, R.F. and Forman, H.J.
Carbon monoxide toxicity.
In: Handbook of Physiology, Section 3: The Respiratory System, Volume 4, Gas Exchange: L.E. Farhi and S.M. Tenney, editors, Am. Physiol. Soc., 1987, pp 439-456.

16. Forman, H.J., Skelton, D., Loeb, G.A. and Dorio, R.J.
Membrane permeability and oxidant injury.
(Oxygen Radicals in Biology and Medicine. M.G. Simic, K.A. Taylor, J.F. Ward and C. von Sonntag, editors, Pergamon).
Basic Life Sciences 49: 523-530, 1988.

17. Forman, H.J.
Oxidant radical production and lung injury.
In: Oxygen Radicals: Systemic Events and Disease Processes: D.K. Das and W.B. Essman, editors, Karger, 1990, pp. 71-96.

18. Forman, H.J. and Torres, M.
Leukocytes, macrophages & active molecular species.
In: Basic Science in Toxicology. Proceedings of 5th International Congress of Toxicology: Taylor and Francis, London, 1990, pp. 250-259.

19. Forman, H.J. and Thomas, M.J.
Oxygen metabolism in the lungs.
In: Comprehensive Treatise on Pulmonary Toxicology, Vol 1. Comparative Biology of the Normal Lung: R.A. Parent, editors, CRC Press, 1991, pp. 485-510.

20. Forman, H.J. and Robison, T.W.
Arachidonic acid metabolites and phagocytic cells as mediators of tissue injury.
( In Vitro Toxicology - Mechanisms and New Technology), Mary Ann Libert, New York.
Alternative Methods in Toxicology 8: 3-17, 1991.

21. Forman, H.J. and Torres, M.
Inflammation: an overview.
In: Oxidative Damage & Repair. Chemical, Biological, and Medical Aspects. (Proceedings of the 5th Biennial General Meeting of the International Society for Free Radical Research), Pergamon Press, New York, 1992, pp. 636-641.

22. Forman, H.J., Robison, T.W., Skelton, D.C. and Duncan, D.P.
Perturbation of arachidonate metabolism and membrane function by oxidants.
In: The Molecular Basis of Oxidative Damage by Leukocytes, A. Jesaitis and E.A. Dratz, editors, CRC Press, Boca Raton, 1992, pp.101-111.

23. Forman, H.J.
Role of the g-glutamyl cycle in antioxidant defense.
In: Biological Free Radical Oxidations and Antioxidants, F. Ursini and E. Cadenas, editors, Cleup, University Publisher, Padova, Italy, 1992, pp. 111-114.

24. Forman, H.J.
Membrane potential changes in hydroperoxide-induced cell injury.
In: Active Oxygens, Lipid Peroxides and Antioxidants, K. Yagi, editor, Japan Scientific Societies Press, Tokyo, and CRC Press, Boca Raton, 1993, pp. 149-160.

25. Forman, H.J., Shi, M., Kugelman, A. and Choy, H.A.
Role of g-glutamyl cycle enzymes in antioxidant defense.
Bull. Soc. Luxembourgeosie Biol. Clin. (Special issue) 69-75, 1993.

26. Forman, H.J., Shi, M., Iwamoto, T., Liu, R.-M. and Robison, T.W.
Measurement of g-glutamyl transpeptidase and g-glutamylcysteine synthetase activities in cells.
Methods Enzymol. 252: 66-71, 1995.

27. Forman, H.J., Shi, M., Kugelman, A., Iwamoto, T. and Choy, H.A.
g-Glutamyl cycle enzymes and antioxidant defense.
In: The Oxygen Paradox, K.J.A. Davies and F. Ursini, editors, CLEUP, University Publisher, Padova, Italy, 1995, pp. 223-234.

28. Forman, H.J., Liu, R. and Shi, M.M.
Glutathione synthesis in oxidative stress.
In: Biothiols in Health and Disease, L. Packer and E. Cadenas, editors, Marcel Dekker, Inc., New York, 1995, pp. 189-212.

29. Forman, H.J., Liu, R.-M. and Tian, L.
Glutathione cycling in oxidative stress.
In: Lung Biology in Health and Diseases, C. Lenfant, editor, (Oxygen, Gene Expression and Cellular Function, D. Massaro and L. Clerch, editors), Marcel Decker, Inc., New York, 1997, pp. 99-121.

30. Forman, H.J. and Azzi, A.
On the virtual existence of superoxide anions in mitochondria: thoughts regarding its role in pathophysiology.
FASEB J. 11: 374-375, 1997.

31. Thomas, M.J., Robison, T.W. and Forman, H.J.
Assessment of tissue injury from reactive oxygen metabolites.
In: Lung Biology in Health and Diseases, C. Lenfant, editor, (Chronic Lung Disease in Early Infancy, R.D. Bland and J. Coalson, editors) Marcel Decker, Inc., New York 1999, pp. 779-792.

32. Forman, H.J. and Azzi, A.
Production of reactive oxygen species in mitochondria and age-associated pathophysiology: a reality check.
In: Understanding the Process of Aging, E. Cadenas and L. Packer, editors, Marcel Dekker, Inc., New York, 1999, pp. 73-93.

33. Girón-Calle, J. and Forman, H.J.
Cell Ca ²⁺ in signal transduction: modulation in oxidative stress.
In: Antioxidant and Redox Regulation of Genes, C.K. Sen, H. Sies, and P.A. Baeuerle, editors, Academic Press, San Diego, 1999, pp. 105-127.

34 Torres, M. and Forman, H.J.
Nitric oxide, oxidative stress and signal transduction.
In: Nitric Oxide, Biology and Pathobiology, L.J. Ignarro, editor, Academic Press, San Diego, 2000, pp. 329-342.

35. Kaul, N. and Forman, H.J.
Reactive oxygen species in physiology and toxicology: from lipid peroxidation to transcriptional activation.
In: Toxicology of the Human Environment: The Critical Role of Free Radicals, C.J. Rhodes, editor, Taylor and Francis, New York 2000, pp. 310-335.

36. Dickinson, D.A., Liu, R.-M., Iles, K.E., and Forman, H.J.
Signaling for the synthesis of glutathione.
In: Free Radicals in Chemistry, Biology and Medicine, T. Yoshikawa, S. Toyokuni, Y Yamamoto and Y. Naito, editors, OICA International, London, 2000, pp. 139-154.

37. Forman, H.J., Gao, L., Broughman, J.R., Iwamoto, T., Venglarik, C.J., and Tomich, J.M.
Glutathione transport and impaired antioxidant function in cystic fibrosis.
Pediatric Pulmonology 30 (S20): 161-162, 2000.

38. Liu, R.-M., Choi, J. and Forman, H.J.
Oxidant induced regulation of glutathione synthesis.
In: Current Protocols in Toxicology, D.J. Reed, editor, John Wiley & Sons, New York, 2001, Unit 6.7 (1-21).

39. Torres, M. and Forman, H.J.
Redox signaling in macrophages.
Mol. Aspects Med. 22: 189-216, 2001.

40. Forman, H.J. and Torres, M.
Signaling by the respiratory burst in macrophages.
IUBMB Life 51: 365-371, 2001.
41. Forman, H.J. and Dickinson, D.A.
Oxidative signaling and glutathione synthesis.
In: Thiol Metabolism and Redox Regulation of Cellular Functions, A. Pompella, G. Bánhegyi, and M. Wellman-Rousseau, editors, NATO Science Series IOS Press, 2002, pp. 1-13.
Republished as Biofactors17: 1-12, 2003.

42. Torres, M. and Forman, H.J.
Redox signaling and the MAP kinase pathways.
In: Thiol Metabolism and Redox Regulation of Cellular Functions, A. Pompella, G. Bánhegyi, and M. Wellman-Rousseau, editors, NATO Science Series IOS Press, 2002, pp. 306-316.
Republished as Biofactors17: 287-296, 2003.

43. Dickinson, D., Iles, K and Forman, H.
Signaling pathways in glutathione biosynthesis.
In: Proceedings of the 11th Biennial Meeting of the Society for Free Radical Research International, C. Pasquier, editor, Bologna, Monduzzi Editore, 2003, pages 245-249.

44. Forman H.J., Dickinson D.A. and Iles, K.E.
HNE - Signaling pathways leading to its elimination.
Mol. Aspects Med. 24:189-194, 2003.

45. Dickinson DA, Iles KE, Wigley AF, Forman HJ.
Analysis of transcription factor remodeling in phase II gene expression with curcumin.
Methods Enzymol. 378: 302-18, 2004.

46. Watanabe N, Dickinson DA, Liu RM, Forman HJ.
Quinones and glutathione metabolism.
Methods Enzymol. 378: 319-40, 2004.

47. Zhang H, Forman HJ, and Choi J.
Gamma-glutamyl transpeptidase in glutathione biosynthesis.
Methods Enzymol. 401: 468-83, 2005

48. Torres, M. and Forman, H.J.
Signal Transduction.
In: Encyclopedia of Respiratory Medicine, Volume 4, G.J. Laurent and S.D. Shapiro, editors, Elsevier, ISBN (Set): 0-12-438360-2, 2006, pp.1-9.

49. Newsam, S., Novini, K., Rich, B., Rinna, A., and Forman, H.J.
Measuring respiratory burst in alveolar macrophages
Proceedings of Workshop on Multiscale Biological Imaging, Data Mining & Informatics
Santa Barbara, September 2006.

50. Forman, H.J.
Hydrogen Peroxide: the Good, the Bad, and the Ugly
In: Oxidants in Biology: a question of balance, G. Valacchi and P.A. Davis editors, Springer, ISBN 978-I-4020-8398-3, 2008, pp 1-18.

INTERNET PUBLICATIONS

1. Dickinson D.A., Lu S.C. and H.J. Forman
Thiols: Glutathione – Synthesis
The Virtual Free Radical School (uploaded July, 2002)
http://www.healthcare.uiowa.edu/research/sfrbm/virtual.html

2. Dickinson D.A., Forman H.J. and S.C. Lu
Thiols: Glutathione – Regulation
The Virtual Free Radical School (uploaded April, 2003, updated March, 2006) http://www.healthcare.uiowa.edu/research/sfrbm/virtual.html

3. H.J. Forman
Glutathione: antioxidant defense and regulation of its synthesis, in Davies, K. (ed.), Free Radicals and the Oxygen Paradox: Oxidative Stress in Biology, Aging and Disease, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London, 2007 (online at http://www.hstalks.com/?t=BL0281672-Forman)
 

BOOK REVIEWS

1. "Thioredoxin and Glutaredoxin Systems: Structure and Function" by A. Holmgren, C.-I. Branden, H. Jornvall, and B.-M. Sjoberg.
J. Free Radic. Biol. Med. 2: 83, 1986.

2. "Biological Oxidants: Generation and Injurious Consequences" by C.G. Cochrane and M.A. Gimbrone, Jr.
Am. J. Physiol. 266: L590, 1994.

3. "Mitochondria and Free Radicals in Neurodegenerative Diseases" by M.F. Beal.
Free Radic. Biol. Med. 24: 876-877, 1998.

4. "Free Radicals and Antioxidant Protocols" by Donald Armstrong.
The Quarterly Review of Biology 74: 341-342, 1999.


LETTERS TO EDITORS

1. Forman, H.J. and Haugaard, N.
Superoxide toxicity.
Trends in Biochemical Sciences 7: 279, 1982.

2. Kaul, N. and Forman, H.J.
Response to Neopterin deratives to activate NF‑ kB.
Free Radic. Biol. Med. 23: 179, 1997.



EDITORIAL

1. Forman, H.J.
Another reason for taking aspirin.
Am. J. Physiol. 280: L1-2, 2001.

2. Forman, H.J. and Ruden, D.
Introduction to serial reviews on EpRE and its signaling pathway.
Free Radic. Biol. Med. 36: 1197-1198, 2004.

3. Forman, H.J. and Dickinson, D.A.
Introduction to serial reviews on 4-hydroxy-2-nonenal as a signaling molecule.
Free Radic. Biol. Med. 37: 594-596, 2004.

4. Forman, H.J.
Introduction to serial reviews on signaling by toxicants.
Free Radic. Biol. Med. 37: 915, 2004.

5. Forman, H.J.
Introduction to serial reviews on peroxiredoxins.
Free Radic. Biol. Med. 38: 1411-1412, 2005.

6. Natarajan, V. and Forman, H.J.
Introduction to serial reviews on redox regulation of phospholipases and sphingomyelinase in cell signaling.
Free Radic. Biol. Med. 40: 363, 2006.

7. Forman, H.J.
Signal transduction and reactive species
Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2009.09.002

8. Forman, H.J.
Critical Methods in Free Radical Biology and Medicine
Free Radic. Biol. Med. doi:10.1016/j.freeradbiomed.2009.09.013


MEETING REPORTS
1. Forman, H.J. Wispe, J.R. and Elsayed, N.
First International Conference on Oxidative Stress and Aging, 22-26 March 1994
SFRR Newsletter 4: 1994.