Gitler Lab

Lab News

May 14, 2012: Teresa Lee is selected to participate in the HHMI Medical Research Fellows Program.

April 21, 2012: Mike's paper on distinct TDP-43 pathological features in ALS cases with ataxin 2 intermediate-length polyQ expansions is published in Acta Neuropathologica. Click here to read the paper.

March 27, 2012: Julien's paper on evaluating a role for the EWSR1 gene in ALS is published in Human Molecular Genetics. Click here to read the paper.

March 23, 2012: Alessandra's paper on Ypk9 and manganese toxicity in yeast published in PLoS One. Click here to read the paper.

January 21, 2012: Review article with Oliver King and Jim Shorter on the expanding role of  RNA-binding proteins with prion-like domains in neurodegenerative diseases is published in Brain Research. Click here to read the paper.

January 1, 2012: Gitler Lab moves to Stanford!

December 27, 2011: Paper on yeast screen for new ALS disease genes featured on the cover of PNAS (Volume 108, issue 52). Click here to see the cover photo in the PNAS cover archive and here to see our lab cover gallery. Paper also featured in a Research Highlight in Disease Models and Mechanisms. Click here to read the highlight. 

December 6, 2011: Nature Reviews Neurology highlights Julien's paper on yeast screen for new candidate ALS disease genes. Click here to read the article.

November 9, 2011: Mini-symposium article with Benjamin Wolozin on local RNA translation at the synapse published in the Journal of Neuroscience. Click here to read the article.

November 7, 2011: Julien's paper (with the Summer high school students) on yeast screen to predict new candidate ALS disease genes published in PNAS. Click here to read the article. Click here to read a highlight of the work on the PNAS website and here to read a story about this work on the Packard Center for ALS Research website. Click here to read a press release from PENN. Click here to read a feature on this work by Alzforum.

November 3, 2011Aaron's Perspectives article published in Science. Click here to read the article. 

November 3, 2011Aaron is selected as a Finalist in the 2011 Eppendorf and Science Prize for Neurobiology. Click here to see the announcement on the Science website and here to read Aaron's essay, "A Simple Yeast Model Provides New Insight into a Complicated Human Neurodegenerative Disease." 

August 17, 2011Aaron wins the 2011 International Paulo Contijo Young Investigator Award from the Instituto Paulo Gontijo. Click here to see the announcement from the IPG and here to see a press release from PENN. 

August 1, 2011: Julien Couthouis awarded a postdoctoral fellowship from the Ellison Medical Foundation/American Federation for Aging Research.

July 27, 2011: Mike Fleming's yeast high-throughput plasmid overexpression screen video protocol published in Journal of Visualized Experiments. Click here to watch the video.

July 19, 2011: Extra-Views article with Jim Shorter on RNA-binding proteins in ALS and FTLD-U accepted in Prion and featured on the cover. Click here to read the article and here to see the cover design in our cover gallery

May 11, 2011: Teresa's paper (with the Summer high school students) on polyQ disease genes in ALS published in Neurology. Click here to read the paper and here to read an accompanying editorial by Kenneth Fischbeck and Stefan Pulst. 

May 10, 2011: Alzforum covers our recent PLoS Biology paper on FUS. Click here to read the story. 

April 26, 2011: Zhihui's paper with Zamia from the Shorter lab on the ALS disease protein FUS/TLS published in PLoS Biology. Click here to read the article, here for a related article by Greg Petsko and colleagues, here for a synopsis of the work by PLoS Biology and here for a press release of the work from PENN.

April 5, 2011: Mike Hart is awarded a National Research Service Award (NRSA) from the National Institute of Neurological Disorders and Stroke (NINDS).

March 29, 2011: Ataxin-2 CAG vs. CAA repeat paper with Nancy Bonini's group published in PLoS One. Click here to read the paper.

February 4, 2011: Gitler lab collaborative project with Nancy Bonini's group to use yeast and fly models to study ALS featured in the February issue of HHMI Bulletin. Click here to read the story.

February 3, 2011: Teresa and Rose's paper on Ataxin-2 polyQ expansions in ALS published in Human Molecular Genetics and featured on the cover!. Click here to see the cover design in our cover gallery and here to read the article.

January 3, 2011: Teresa's paper (with the Summer high school students) on polyQ disease genes in ALS accepted in Neurology.

December 11, 2010: Gitler Lab awarded an Addgene Challenge Award as part of the Addgene Innovation Awards Program.

November 27, 2010: Maria and Mike's paper on TDP-43 toxicity in yeast published in Methods. Click here to read the article.

November 2, 2010: Rose Li awarded scholarship to attend Keystone Symposium on Neurodegenerative Diseases: The Molecular Basis for Neurodegeneration in Taos, NM.

October 8, 2010: The Packard Center for ALS Research at Johns Hopkins funds our collaboration with Jim Shorter's group to study the ALS disease protein FUS/TLS.

September 23, 2010: Gitler lab research mentioned by PENN president Dr. Amy Gutmann during her White House meeting with Vice President Joe Biden. Click here to watch the video clip (video is ~25 minutes and lab mention is at 24m04s). 

August 25, 2010: Our paper on TDP-43 and Ataxin-2 published in Nature. Click here to read the article, here to read the accompanying News & Views article by Clotilde Lagier-Tourenne and Don Cleveland. Click here for a press release of the work from PENN and here for a press release from the Packard Center for ALS Research at Johns Hopkins.

August 1, 2010: Aaron selected as Scientist to Watch by The Scientist Magazine. Click here to link to the article (subscription required). Click here to watch the YouTube video associated with the article.

June 1, 2010: Maria passes her prelim exam!

May 18, 2010: Mike passes his prelim exam!

April 23, 2010: Mike selected as a 2010 predoctoral trainee for Dr. Meera Sundaram's T32 Predoctoral Training Grant: Genetics Training Program

April 15, 2010: Brian's review with Mimi from Jim Shorter's lab on prion-like properties of neurodegenerative disease proteins published in The Journal of Cell Science. Click here to read the article.

October 16, 2009: Mike Hart wins 1st prize in the Center for Neurodegenerative Disease Research Retreat Poster Contest.

May 22, 2009: Brian and Jon's paper with David and Jim in the Shorter lab on ALS-linked TDP-43 mutations published in JBC. Click here to read the paper and here for a story on the paper featured on Alzforum.

May 4, 2009:  Alessandra Chesi awarded another year of postdoctoral fellowship funding from the Parkinson's Disease Foundation to continue investigating the PARK9/ATP13A2 gene.

February 1, 2009: Alessandra and Aaron's paper on a connection between genetic and environmental causes of Parkinson's disease published in Nature Genetics. Click here to read the paper and here for press release on the work.

November 20, 2008: Alessandra Chesi wins 2nd prize in the Center for Neurodegenerative Disease Research Retreat Poster Contest for her poster entitled, "Investigating the function of YPK9, the yeast orthologue of the human Parkinson's disease gene PARK9 / ATP13A2".

September 22, 2008:  Aaron is awarded 2008 NIH Director's New Innovator Award. Click here to see the NIH announcement and here for press release from Penn.

July 17, 2008: Aaron selected as a 2008 Rita Allen Foundation Scholar. Click here for press release from Penn.

July 1, 2008: Aaron selected as a 2008 Pew Scholar in the Biomedical Sciences. Click here to see the Pew announcement and here for press release from Penn. 

June 15, 2008: Zhihui Sun awarded postdoctoral fellowship from the American Parkinson's Disease Association. Click here to see APDA fellowship announcement online.

June 3, 2008: Zhihui Sun's paper on zebrafish synuclein genes is published in Developmental Dynamics. Click here to read the paper online.

April 29, 2008: Brian Johnson's paper on yeast TDP-43 model is published in PNAS. Click here to read the paper and here for press release on Brian's work.

April 16, 2008: Alessandra Chesi awarded postdoctoral fellowship from the Parkinson's Disease Foundation.

November 12, 2007: Zhihui Sun wins 1st prize in the Center for Neurodegenerative Disease Research Retreat Poster Contest for her poster entitled, "Discovery and Characterization of Three Novel Synuclein Genes in Zebrafish".

July 1, 2007: The Gitler Lab officially opens!


Gitler Lab in the news

Philadelphia Inquirer
Daily Intelligencer
http://www.sciencedaily.com/releases/2009/02/090201141559.htm
http://www.the-scientist.com/2008/11/1/59/1/
http://www.upenn.edu/pennnews/current/research/050808.html

Popular Science 
http://www.sciencedaily.com/releases/2008/04/080417163854.htm
http://www.genengnews.com/news/bnitem.aspx?name=33975594
http://www.cba-news.com/issues/5_17/features/146541-1.html
http://www.alzforum.org/new/detail.asp?id=1804