One of the body’s obesity-associated hormones, adiponectin may lead to osteoporosis, which causes an increase in the risk of fracture, the Science Daily website says, based on the discovery of a research group from Sahlgrenska Academy at the University of Gothenburg in Sweden. However, "the detection of graphite in metal-on-metal hips might lead to more durable devices". Mostly a protein hormone, adiponectin is produced and secreted exclusively by adipocytes (fat cells) that control the metabolism of lipids and glucose. It influences the body's response to insulin.The hormone also has anti-inflammatory effects on the cells lining the walls of blood vessels, according to MedicineNet.com. High blood levels of adiponectin are linked with an abridged risk of heart attack, according to a medical research. Low levels of adiponectin are found in people who are obese and who are at increased risk of a heart attack, MedicineNet.com reports. The human skeletal system is more than just bones, vertebrae and joints. It is an active organ that is constantly linked to the brain, muscles and fatty tissue. Stem cells -- the body's most important cells -- are formed in the skeleton, which is also home to hormones that control the body's blood sugar and obesity by sending signals to other organs, reports the Science Daily website. New research has now revealed that raised levels of obesity hormone in the blood could be connected to osteoporosis. Dan Mellström, a researcher at the Sahlgrenska Academy and consultant at the Sahlgrenska University Hospital, both in Sweden, is a leading expert in osteoporosis. Being a part of an intercontinental research project studying the danger issues allied with osteoporosis in elderly men, he and his colleagues have been looking into the obesity hormone adiponectin. This research has now shown that men and women with raised levels of this hormone also have more fragile skeletons and more fractures, as well as reduced muscle strength and lower muscle mass, thereby increasing the risk of fractures. High adiponectin presence also appears to be associated to better useful aging, according to the Science Daily website. High levels of adiponectin among the elderly seem to be related with both abridged operational of the musculature and a more fragile skeleton, Mellstrom says. This means an advanced danger of fractures and falls, and also augment mortality, says the Science Daily online resource. The results are based on the Mr OS study, led from the Sahlgrenska Academy, which had watched into the risk factors for osteoporosis in elderly men. The study includes around 11,000 men in Sweden, the USA and Hong Kong. This fracture may trigger hip pains that provokes patients to go through with hip replacement and falling defective implants, against which patients filed Pinnacle Lawsuit. URL REFERENCES: http://www.medterms.com/script/main/art.asp?articlekey=17982 http://www.sciencedaily.com/releases/2011/11/111101171036.htm |