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Signaling

Dynamics of phosphorelays
Collaborators: Orkun S. Soyer (Exeter) and Luca Cardelli (Microsoft Research Cambridge)
Related papers:

Csikász-Nagy A, Cardelli L, Soyer OS: Response dynamics of phosphorelays suggest their potential utility in cell signaling. J R Soc Interface 2011, 8(57):480-8. PDF

DNA damage response
Models and experiments to understand the Post Replication Repair pathway
Collaborators: Flavio Amara, Paolo Plevani, Marco Muzzi-Falconi, Daniela Besozzi (all Milan)

p53 driven transcription dynamics
We try to determine the crucial steps in p53 transcriptional target site recognition
Collaborators: Sree Harish Muppirisetty (CoSBi), Federico Vaggi (CoSBi), Alberto Inga (CIBIO)