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Publications

2012
Romanel A, Cardelli L, Jensen LJ, Csikász-Nagy A: Transcriptional regulation is a major controller of cell cycle transition dynamics. PLoS One 2012 7(1): e29716 PDF
Cavaliere M, Sedwards, S, Tarnita CE, Nowak MA, Csikász-Nagy A: Prosperity is associated with instability in dynamical networks. J Theor Biol 2012, 299:126-138 PDF Website

2011
Moriya H, Chino A, Kapuy O, Csikasz-Nagy A, Novak B: Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico, Molecular Systems Biology 2011, 7:556 PDF

Csikász-Nagy A, Palmisano A,  Zámborszky J: Molecular network dynamics of cell cycle control: transitions to start and finish. Methods Mol Biol 2011, 761:277-91 PDF

Csikász-Nagy A, Cardelli L, Soyer OS: Response dynamics of phosphorelays suggest their potential utility in cell signaling. J R Soc Interface 2011, 8(57):480-8. PDF


2010
 
Conradie R, Bruggeman FJ, Ciliberto A, Csikász-Nagy A, Novák B, Westerhoff HV, Snoep JL.Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex. FEBS J. 2010 277(2):357-67PDF
 

Csikász-Nagy A, Mura I.Role of mRNA gestation and senescence in noise reduction during the cell cycle. In Silico Biol. 2010 10:0006.PDF


2009

Soyer OS, Kuwahara H, Csikász-Nagy A.Regulating the total level of a signaling protein can vary its dynamics in a range from switch like ultrasensitivity to adaptive responses. FEBS J. 2009 276(12):3290-8.PDF

Hong CI, Zámborszky J, Csikász-Nagy A.Minimum criteria for DNA damage-induced phase advances in circadian rhythms. PLoS Comput Biol. 2009 5(5):e1000384.PDF

Csikász-Nagy A.Computational systems biology of the cell cycle. Brief Bioinform. 2009 10(4):424-34PDF

Csikász-Nagy A, Kapuy O, Tóth A, Pál C, Jensen LJ, Uhlmann F, Tyson JJ, Novák B.Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation. Mol Syst Biol. 2009;5:236.PDF

Ballarini P, Mazza T, Palmisano A, Csikász-Nagy A.Studying irreversible transitions in a model of cell cycle regulation. ENTCS. 2009 232:39-53.PDF


2008

Csikász-Nagy A, Novák B, Tyson JJ.Reverse engineering models of cell cycle regulation. Adv Exp Med Biol. 2008;641:88-97.PDF

Mura I, Csikász-Nagy A.Stochastic Petri Net extension of a yeast cell cycle model. J Theor Biol. 2008 254(4):850-60.PDF

Csikász-Nagy A, Soyer OS.Adaptive dynamics with a single two-state protein. J R Soc Interface. 2008 5 Suppl 1:S41-7.PDF

Lovrics A, Csikász-Nagy A, Zsély IG, Zádor J, Turányi T, Novák B.Analysis of a budding yeast cell cycle model using the shapes of local sensitivity functions. Int J Chem Kinet. 2008 40(11):710-20.PDF
Csikász-Nagy A, Gyorffy B, Alt W, Tyson JJ, Novák B.Spatial controls for growth zone formation during the fission yeast cell cycle.Yeast. 2008 25(1):59-69.PDF

2007

Zámborszky J, Hong CI, Csikász Nagy A.Computational analysis of mammalian cell division gated by a circadian clock: quantized cell cycles and cell size control. J Biol Rhythms. 2007 22(6):542-53.PDF

Novak B, Tyson JJ, Gyorffy B, Csikasz-Nagy A.Irreversible cell-cycle transitions are due to systems-level feedback.Nat Cell Biol. 2007 9(7):724-8.PDF

Csikász-Nagy A, Kapuy O, Gyorffy B, Tyson JJ, Novák B.Modeling the septation initiation network (SIN) in fission yeast cells.Curr Genet. 2007 51(4):245-55.PDF


2006

Lovrics A, Csikász-Nagy A, Zsély IG, Zádor J, Turányi T, Novák B. Time scale and dimension analysis of a budding yeast cell cycle model.BMC Bioinformatics. 2006 7:494.PDF

Csikász-Nagy A, Battogtokh D, Chen KC, Novák B, Tyson JJ.Analysis of a generic model of eukaryotic cell-cycle regulation.Biophys J. 2006 90(12):4361-79.PDF Website


2004

Chen KC, Calzone L, Csikasz-Nagy A, Cross FR, Novak B, Tyson JJ.Integrative analysis of cell cycle control in budding yeast.Mol Biol Cell. 2004 15(8):3841-62.PDF Website


2002

Tyson JJ, Csikasz-Nagy A, Novak B.The dynamics of cell cycle regulation.Bioessays. 2002 24(12):1095-109.PDF

Sveiczer A, Csikasz-Nagy A, Novak B.Morphogenetic checkpoint in fission yeast? Yes!Microbiology. 2002 148(Pt 8):2270-1.PDF


2000

Sveiczer A, Csikasz-Nagy A, Gyorffy B, Tyson JJ, Novak B.Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Delta mutant cells.Proc Natl Acad Sci U S A. 2000 97(14):7865-70.PDF

Chen KC, Csikasz-Nagy A, Gyorffy B, Val J, Novak B, Tyson JJ.Kinetic analysis of a molecular model of the budding yeast cell cycle.Mol Biol Cell. 2000 11(1):369-91.PDF


1999

Novák B, Tóth A, Csikász-Nagy A, Györffy B, Tyson JJ, Nasmyth K.Finishing the cell cycle.J Theor Biol. 1999 199(2):223-33. PDF


1998

Novak B, Csikasz-Nagy A, Gyorffy B, Nasmyth K, Tyson JJ.Model scenarios for evolution of the eukaryotic cell cycle.Philos Trans R Soc Lond B Biol Sci. 1998 353(1378):2063-76.PDF

Novak B, Csikasz-Nagy A, Gyorffy B, Chen K, Tyson JJ.Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions.Biophys Chem. 1998 72(1-2):185-200.PDF