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| Silvarolla MB, Mazzafera P, Fazuoli LC. | A naturally decaffeinated arabica coffee. | Nature | 429 | 826 | 2004 | 交配による品種改良：カフェインレスのコーヒーノキ（アラビカ種）の作出 | Silvarolla2004 | | ★★★★★ |  |
| Kondamudi N, Mohapatra SK, Misra M. | Spent Coffee Grounds as a Versatile Source of Green Energy. | J. Agric Food Chem. | 56 | 11757-60 | 2008 | コーヒー滓からバイオディーゼルを生産 | Kondamudi2008 | | ★★★★ | |
| Gniechwitz D, Reichardt N, Blaut M, Steinhart H, Bunzel M. | Dietary Fiber from Coffee Beverage: Degradation by Human Fecal Microbiota. | J. Agric. Food Chem. | 55 | 6989-96 | 2007 | コーヒーの食物繊維は一部のヒト腸内細菌の増殖を促進する | Gniechwitz2007 | | ★★★ | |
| Atanasov AG, Dzyakanchuk AA, Schweizer RA, Nashev LG, Maurer EM, Odermatt A. | Coffee inhibits the reactivation of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: A glucocorticoid connection in the anti-diabetic action of coffee? | FEBS Lett. | 580 | 4081-5. | 2006 | コーヒー抽出物に11βHSD1阻害活性 | Atanasov2006 | | ★★ | |
| Galindo-Cuspinera V, Winnig M, Bufe B, Meyerhof W, Breslin PA. | A TAS1R receptor-based explanation of sweet 'water-taste' | Nature | 441 | 354-7 | 2006 | 水を甘く感じるのは甘味受容体結合性阻害物質の解離による | Galindo2006 | | ★★★ | |
| Farah A, de Paulis T, Moreira DP, Trugo LC, Martin PR. | Chlorogenic Acids and Lactones in Regular and Water-Decaffeinated Arabica Coffees. | J Agric Food Chem. | 54 | 374-381 | 2006 | 水抽出のデカフェ処理過程ではクロロゲン酸類の減少はほとんど無視できる | farah2006 | | ★★★ | |
| Uefuji H, Tatsumi Y, Morimoto M, Kaothien-Nakayama P, Ogita S, Sano H. | Caffeine Production in Tobacco Plants by Simultaneous Expression of Three Coffee N-methyltrasferases and Its Potential as a Pest Repellant. | Plant Mol Biol. | 59 | 221-7 | 2005 | カフェインを作るタバコの作製。カフェインの昆虫忌避作用の可能性 | Uefuji2005 | | ★★ | |
| Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O. | Adenosine A(2A), but not A(1), receptors mediate the arousal effect of caffeine. | Nat Neurosci | 8 | 858-9. | 2005 | カフェインの覚醒作用は中枢A2A受容体阻害による | Huang2005 | | ★★★★★ | |
| D'Agostina A, Boschin G, Bacchini F, Arnoldi A. | Investigations on the high molecular weight foaming fractions of espresso coffee. | J Agric Food Chem. | 52 | 7118-25 | 2004 | エスプレッソコーヒーの泡の成分を分析 | D'Agostina2004 | | ★★★ | |
| Massimo F Marcone | Composition and properties of Indonesian palm civet coffee (Kopi Luwak) and Ethiopian civet coffee. | Food Research International | 37 | 901-12 | 2004 | コピ・ルアクの性状解析 | Massimo2004 | | ★ | |
| Kurahashi N, Inoue M, Iwasaki M, Sasazuki S, Tsugane S; for JPHC Study Group. | Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan. | Cancer Sci. | (Epub) | | 2008 | コーヒー・カフェインの摂取は膀胱がんのリスクを上げる可能性がある | Kurahashi2008 | コホート | ★★★★★ | |
| Shimazu T, Inoue M, Sasazuki S et al. | Coffee consumption and risk of endometrial cancer: A prospective study in Japan. | Int J Cancer | 123 | 2406-10 | 2008 | コーヒー飲用する女性では子宮体がんの発症リスクが低下 | Shimazu2008 | コホート | ★★★★ | |
| Wu JN, Ho SC, Zhou C, Ling WH, Chen WQ, Wang CL, Chen YM. | Coffee consumption and risk of coronary heart diseases: A meta-analysis of 21 prospective cohort studies. | Int. J Cardiol. | (Epub) | | 2008 | コーヒー飲用は心疾患のリスクファクターにはならない | Wu2008 | メタアナリシス | ★★★ | |
| Larsson SC, Wolk A | Coffee consumption and risk of liver cancer: a meta-analysis. | Gastroenterology | 132 | 1740-5 | 2007 | コーヒー飲用者では肝がん発生リスクが減少する | Larsson2007 | メタアナリシス | ★★★★★ | |
| Sofi F, Conti AA, Gori AM, Eliana Luisi ML, Casini A, Abbate R, Gensini GF. | Coffee consumption and risk of coronary heart disease: A meta-analysis. | Nutr. Metab. Cardiovasc. Dis. | 17 | 209-23 | 2007 | コーヒー飲用と心疾患の発生リスク上昇には有意な関連なし | Sofi2007 | メタアナリシス | ★★★★★ | |
| Lopez-Garcia E, van Dam RM, Rajpathak S, Willett WC, Manson JE, Hu FB. | Changes in caffeine intake and long-term weight change in men and women. | Am J Clin Nutr. | 83 | 674-80 | 2006 | カフェイン摂取者の長期間における体重変化は非摂取者と比べわずかに減少方向を示す。 | Lopez2006 | コホート | ★★★ | |
| Cornelis MC, El-Sohemy A, Kabagambe EK, Campos H. | Coffee, CYP1A2 genotype, and risk of myocardial infarction | JAMA | 295 | 1135-41 | 2006 | カフェイン代謝能力が低い人でコーヒー飲用により心疾患リスクが上昇 | Cornelis2006 | 症例対照研究 | ★★★★ | |
| Murakami K, Okubo H, Sasaki S. | Dietary intake in relation to self-reported constipation among Japanese women aged 18-20 years. | Eur J Clin Nutr | 60 | 650-7 | 2006 | コーヒー飲用している日本人女性では便秘が少ない | Murakami2006 | 横断調査 | ★★★ | |
| Brown SR, Cann PA, Read NW. | Effect of coffee on distal colon function. | Gut | 31 | 450-3. | 1990 | コーヒーには緩下作用がみられる（飲用者の約3割） | Brown1990 | 横断調査、介入実験 | ★★★★★ | |
| van Dam RM, Hu FB. | Coffee consumption and risk of type 2 diabetes: a systematic review. | JAMA | 294 | 97-104 | 2005 | コーヒー飲用によって2型糖尿病の発症リスクが低下 | vanDam2005 | 総説 | ★★★★★ | |
| Signorello LB, McLaughlin JK. | Maternal caffeine consumption and spontaneous abortion: a review of the epidemiologic evidence. | Epidemiology. | 15 | 229-39. | 2004 | 1980-2001までの15の疫学調査から高用量のカフェイン摂取が流産リスクを上昇させることを示した | PMID15127917 | 総説 | ★★★★★ | |
| Tuomilehto J, Hu G, Bidel S, Lindström J, Jousilahti P. | Coffee Consumption and Risk of Type 2 Diabetes Mellitus Among Middle-aged | JAMA | 291 | 1213-1219 | 2004 | コーヒー飲用者で２型糖尿病の発症リスク低下 | Tuomilehto2004 | コホート | ★★★★ | |
| van Dam RM, Feskens EJ. | Coffee consumption and risk of type 2 diabetes mellitus. | Lancet | 360 | 1477-8 | 2002 | コーヒー飲用で２型糖尿病のリスク低下？ | vanDam2002 | コホート | ★★★★★ | |
| Ogita S, Uefuji H, Yamaguchi Y, Koizumi N, Sano H. | Producing decaffeinated coffee plants | Nature | 423 | 823 | 2003 | 世界初の遺伝子組換えによるカフェインの少ないコーヒーノキの作出 | Ogita2003 | | ★★★★★ | |
| Isogawa A, Noda M, Takahashi Y, Kadowaki T, Tsugane S. | Coffee consumption and risk of type 2 diabetes mellitus. | Lancet. | 361 | 703-4. | 2003 | 日本でもコーヒー飲用者で2型糖尿病発症リスクが低下 | Isogawa2003 | 横断研究（コホート内） | ★★★ | |
| Corti R, Binggeli C, Sudano I, Spieker L, Hanseler E, Ruschitzka F, Chaplin WF, Luscher TF, Noll G | Coffee Acutely Increases Sympathetic Nerve Activity and Blood Pressure Independently of Caffeine Content. Role of Habitual Versus Nonhabitual Drinking | Circulation | 106 | 2935-40 | 2002 | 常用／非常用者で血圧上昇活性に差 | Corti2002 | | ★★★★ | |
| Gallus S, Bertuzzi M, Tavani A, Bosetti C, Negri E, La Vecchia C, Lagiou P, Trichopoulos D. | Does coffee protect against hepatocellular carcinoma? | Br J Cancer | 87 | 956-9 | 2002 | コーヒー飲用で肝細胞がん発生リスク低下？ | Gallus2002 | 症例対照研究 | ★★★★ | |
| Borrelli RC, Visconti A, Mennella C, Anese M, Fogliano V. | Chemical characterization and antioxidant properties of coffee melanoidins. | J Agric Food Chem | 50 | 6527-33 | 2002 | コーヒーメラノイジンは焙煎進行により化学的特性や生理的活性が変化する | Borrelli2002 | | ★★ | |
| Foukas LC, Daniele N, Ktori C, Anderson KE, Jensen J, Shepherd PR. | Direct Effects of Caffeine and Theophylline on p110delta and Other Phosphoinositide 3-Kinases. DIFFERENTIAL EFFECTS ON LIPID KINASE AND PROTEIN KINASE ACTIVITIES. | J Biol Chem | 277 | 37124-30 | 2002 | カフェイン／テオフィリンの新しい作用メカニズムの発見 | Foukas2002 | | ★★★★★ | |
| Hernan MA, Takkouche B, Caamano-Isorna F, Gestal-Otero JJ. | A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease. | Ann Neurol. | 52 | 276-284 | 2002 | コーヒー飲用者でパーキンソン病発症リスク低下 | Hernan2002 | メタアナリシス | ★★★★ | |
| Lindskog M, Svenningsson P, Pozzi L, Kim Y, Fienberg AA, Bibb JA, Fredholm BB, Nairn AC, Greengard P, Fisone G. | Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. | Nature | 418 | 774-8 | 2002 | カフェインの中枢作用メカニズム解明の大きな進展 | Lindskog2002 | | ★★★★★ | |
| Maia L, De Mendonca A. | Does caffeine intake protect from Alzheimer's disease? | Eur J Neurol | 9 | 377-382 | 2002 | カフェインがアルツハイマーを予防？ | Maia2002 | 症例対照研究 | ★★★★★ | |
| Lin Y, Tamakoshi A, Kawamura T, Inaba Y, Kikuchi S, Motohashi Y, Kurosawa M, Ohno Y. | Risk of pancreatic cancer in relation to alcohol drinking, coffee consumption and medical history: Findings from the Japan collaborative cohort study for evaluation of cancer risk. | Int J Cancer | 99 | 742-6 | 2002 | コーヒーの大量飲用者で膵臓ガンによる死亡リスク増加 | Lin2002 | コホート | ★★★ | |
| Hollingsworth RG, Armstrong JW, Campbell E. | Pest Control: Caffeine as a repellent for slugs and snails. | Nature | 417 | 915-6 | 2002 | カフェインにカタツムリへの忌避および致死活性 | Hollingsworth2002 | | ★★★★ | |
| Ogawa M, Herai Y, Koizumi N, Kusano T, Sano H. | 7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties. | J Biol Chem | 276 | 8213-8 | 2001 | カフェイン生合成経路の解明 | Ogawa2001 | | ★★★★★ | |
| Ross GW, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR. | Association of coffee and caffeine intake with the risk of Parkinson disease. | JAMA | 283 | 2674-9 | 2000 | コーヒーにパーキンソン病予防の可能性 | Ross2000 | コホート | ★★★★★ | |
| de Paulis T, Schmidt DE, Bruchey AK, Kirby MT, McDonald MP, Commers P, Lovinger DM, Martin PR. | Dicinnamoylquinides in roasted coffee inhibit the human adenosine transporter. | Eur J Pharmacol | 442 | 215-223 | 2002 | フェルロイルキナ酸ラクトンの中枢性鎮静作用 | dePaulis2002 | | ★★★ | |
| Boublik JH, Quinn MJ, Clements JA, Herington AC, Wynne KN, Funder JW. | Coffee contains potent opiate receptor binding activity. | Nature | 301 | 246-8 | 1983 | コーヒーに麻薬様成分？？ | Boublik1983 | | ★★★ | |
| Wynne KN, Familari M, Boublik JH, Drummer OH, Rae ID, Funder JW. | Isolation of opiate receptor ligands in coffee. | Clin Exp Pharmacol Physiol | 14 | 785-90 | 1987 | コーヒーの麻薬様成分はイソフェルロイルキナ酸ラクトン？ | Wynne1987 | | ★★ | |
| Roubik DW | Tropical agriculture: The value of bees to the coffee harvest | Nature | 417 | 708 | 2002 | アフリカミツバチがアラビカ種の受粉に関与 | Roubik2002 | | ★★ | |
| Frank O, Blumberg S, Kunert C, Zehentbauer G, Hofmann T. | Structure determination and sensory analysis of bitter-tasting 4-vinylcatechol oligomers and their identification in roasted coffee by means of LC-MS/MS. | J Agric Food Chem | 55 | 1945-1954 | 2007 | ビニルカテコールオリゴマーがコーヒーの苦味成分であることを発見 | Frank2007 | | ★★★★★ | |
| Frank O, Zehentbauer G, Hofmann T | Bioresponse-guided decomposition of roast coffee beverage and identification of key bitter taste compounds | Eur Food Res Technol | 222 | 492-508 | 2006 | コーヒーの苦味成分としてクロロゲン酸ラクトン類を同定 | Frank2006 | | ★★★★★ | |
| Kato M, Noda M, Inoue M, Kadowaki T, Tsugane S. | Psychological Factors, Coffee and Risk of Diabetes Mellitus among Middle-Aged Japanese: a Population-Based Prospective Study in the JPHC Study Cohort. | Endocr. J. | | | 2009 | 日本人コーヒー飲用者で糖尿病発症リスクが低下 | Kato2009 | コホート | ★★★ | |
| Cubry P, Musoli P, Legnaté H, Pot D, de Bellis F, Poncet V, Anthony F, Dufour M, Leroy T. | Diversity in coffee assessed with SSR markers: structure of the genus Coffea and perspectives for breeding. | Genome | 51 | 50-63 | 2008 | SSR法を用いてCoffea属の近縁関係を解析 | Cubry2008 | | ★★★ | |
| Lashermes P, Combes MC, Robert J, Trouslot P, D'Hont A, Anthony F, Charrier A. | Molecular characterisation and origin of the Coffea arabica L. genome. | Mol Gen Genet | 261 | 259-266 | 1999 | アラビカ種はカネフォーラ種とC.eugenioides由来の複二倍体に由来する | Lashermes1999 | | ★★★★★ | |
| Davis AP, Govaerts R, Bridson DM, Stoffelen P | An annotated taxonomic conspectus of the genus Coffea (Rubiaceae) | Bot J Linn Soc | 152 | 465-512 | 2006 | コーヒーノキ属の植物学的分類の最新版 | Davis2006 | | ★★★★★ | |
| Ashihara H, Crozier A | Biosynthesis and catabolism of caffeine in low-caffeine-containing species of Coffea. | J Agric Food Chem | 47 | 3425-3431 | 1999 | カフェイン含量の少ないコーヒーノキ属植物の解析 | Ashihara1999 | | ★★★ | |
| Farah A, Monteiro MC, Calado V, Franca AS, Trugo LC | Correlation between cup quality and chemical attributes of Brazilian coffee | Food Chem. | 98 | 373-380 | 2006 | ブラジルコーヒーの品質と含有成分濃度の相関 | Farah2006 | | ★★★ | |
| Koshiro Y, Jackson MC, Katahira R, Wang ML, Nagai C, Ashihara H | Biosynthesis of chlorogenic acids in growing and ripening fruits of Coffea arabica and Coffea canephora plants | Z Naturforsch [C] | 62 | 731-742 | 2007 | コーヒーノキのクロロゲン酸類代謝経路の解析 | Koshiro2007 | | ★★★ | |
| Lepelley M, Cheminade G, Tremillon N, Simkin A, Caillet V, McCarthy J | Chlorogenic acid synthesis in coffee: An anlysis of CGA content and real-time RT-PCR expression of HCT, HQT, C3H1, and CCoAOMT1 genes during grain development in C. canephora | Plant Sci | 172 | 978-996 | 2007 | クロロゲン酸合成酵素のクローニングと生合成経路解析 | Lepelley2007 | | ★★★★ | |
| Maurin O, Davis AP, Chester M, Mvungi EF, Jaufeerally-Fakim Y, Fay MF | Towards a phylogeny for Coffea (Rubiaceae): Identifying well-supported lineages based on nuclear and plastid DNA sequences | Ann Bot | 100 | 1565-1583 | 2007 | コーヒーノキ属の系統分類 | Maurin2007 | | ★★★★ | |