2009

30. Piepenbrink KH, Gloor BE, Armstrong KM, & Baker BM (2009) Methods for Quantifying T cell Receptor Binding Affinities and Thermodynamics. Methods in Enzymology 466, 359. [link]

29. Insaidoo FK, Zajicek J, & Baker BM (2009) A general and efficient approach for NMR studies of peptide dynamics in class I MHC peptide binding grooves. Biochemistry 48, 9708. [link]

28. Piepenbrink KH, Borbulevych OY, Sommese RF, Clemens J, Armstrong KM, Desmond C, & Baker BM (2009) Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner. Biochemical Journal 423, 353. [link]

27. Bowerman NA, Crofts TS, Chlewicki L, Do, P, Baker BM, Garcia KC, & Kranz DM (2009) Engineering the binding properties of the T cell receptor:peptide:MHC ternary complex that governs T cell activity. Molecular Immunology 46, 3000. [link]

2008

26. Armstrong KM, Piepenbrink KH, & Baker BM (2008) Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes. Biochemical Journal 415, 183. [link]

25. Armstrong KM, Insaidoo FK, & Baker BM (2008) Thermodynamics of T cell receptor - peptide/MHC interactions: progress and opportunities. Journal of Molecular Recognition 21, 275. [link]

24. Loaiza A, Armstrong KM, Baker BM, & Abu-Omar MM (2008) Kinetics of thermal unfolding of phenylalanine hydroxylase variants containing different metal cofactors (FeII, CoII, and ZnII) and their isokinetic relationship. Inorganic Chemistry 47, 4877. [link]

2007

23. Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, & Baker BM (2007) Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. Journal of Molecular Biology 372, 1123. [link]

22. Armstrong KM & Baker BM (2007) A comprehensive calorimetric investigation of an entropically driven T cell receptor - peptide/major histocompatibility complex interaction. Biophysical Journal 93, 597. [link]

21. Davis-Harrison RL, Insaidoo FK, & Baker BM (2007) T cell receptor binding transition states and recognition of peptide/MHC. Biochemistry 46, 1840. [link]

2006

20. Gagnon SJ, Borbulevych OY, Davis-Harrison RL, Baxter TK, Turner RV, Damirjian M, Wojnarowicz A, Biddison WE, & Baker BM (2006) T cell receptor recognition via cooperative conformational plasticity. Journal of Molecular Biology 363, 228. [link]

2005

19. Borbulevych O, Baxter TK, Yu Z, Restifo NP, & Baker BM (2005) Increased immunogenicity of an anchor-modified tumor associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design. Journal of Immunology 174, 4812. [link]

18. Gagnon SJ, Borbulevych OY, Davis-Harrison RL, Baxter TK, Clemens JR, Armstrong KM, Turner RV, Damirjian M, Biddison WE, & Baker BM (2005) Unraveling a hotspot for TCR recognition on HLA-A2: Evidence against the existence of peptide-independent TCR binding determinants. Journal of Molecular Biology 353, 556. [link]

17. Davis-Harrison RL, Armstrong KM, & Baker BM (2005) Two different T cell receptors use different thermodynamic strategies to recognize the same ligand. Journal of Molecular Biology 346, 533. [link]

16. Folker ES, Baker BM, & Goodson HV (2005) Interactions between CLIP-170, tubulin, and microtubules: Implications for the mechanism of CLIP-170 plus-end tracking behavior. Molecular Biology of the Cell 16, 5373. [link]

2004

15. Yu Z, Theoret MR, Touloukian CE, Surman DR, Garman G, Baxter TK, Baker BM, & Restifo NP (2004) Poor immunogenicity of a self/tumor antigen derives from peptide/MHC-I instability and is independent of tolerance. Journal of Clinical Investigation 114, 551. [link]

14. Baxter TK, Gagnon SJ, Davis-Harrison RL, Turner RV, Biddison WE, & Baker BM (2004) Strategic mutations in the class I MHC HLA-A2 independently affect both peptide binding and T cell receptor recognition. Journal of Biological Chemistry 279, 29175. [link]

13. Swalley SE, Baker BM, Calder LJ, Harrison SC, Skehel JJ, & Wiley DC (2004) Full-length influenza hemagglutinin HA2 refolds into the trimeric low-pH-induced conformation. Biochemistry 43, 5902. [link]

2003

12. Binz AK, Rodriguez RC, Biddison WE, & Baker BM (2003) Thermodynamic and kinetic analysis of a peptide-class I MHC interaction highlights the noncovalent nature and conformational dynamics of the class I heterotrimer. Biochemistry 42, 4954. [link]

2002

11. Wang Z, Turner RV, Baker BM, & Biddison WE (2002) MHC allele-specific molecular features determine peptide/HLA-A2 conformations that are recognized by HLA-A2-restricted T cell receptors. Journal of Immunology 169, 3146. [link]

 

For earlier publications, see the full list at PubMed