November 2009 New paper in Methods in Enzymology outlining methods for quantifying the interactions between T cell receptors and their ligands October 2009 New paper in Biochemistry describing a method for generating and collecting high resolution NMR data to study the dynamics of antigenic peptides bound to class I MHC proteins New paper in Biochemical Journal revealing how addition of fluorine atoms to antigenic peptides can selectively modulate T cell receptor recognition September 2009 New grant from the National Institutes of Health to study the role of molecular flexibility in T cell signal transduction. Yahoo -- more work! Time magazine has a story describing the work of our collaborators at the National Cancer Institute and outlines the promise of cancer vaccines and genetic engineering of T cells August 2009 New paper in Molecular Immunology on engineering with TCR-peptide/MHC interface. A collaborative work between our laboratory and that of David Kranz at the University of Illinois Urbana-Champaign April 2009 Grant renewal from the National Institutes of Health. Students and postdocs rejoice! New grant from the Indiana Clinical Sciences and Translational Initiative. Go translational medicine!! December 2008 Kathryn Armstrong defends PhD thesis. Congrats Kathryn!!!! September 2008 New review on the role of conformational changes and molecular flexibility in TCR recognition of peptide/MHC published in Biochemical Journal July 2008 New review on the thermodynamics of TCR-peptide/MHC interactions published in the Journal of Molecular Recognition June 2008 Kurt Piepenbrink receives NIH CBBI fellowship |
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