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Drug Treatments for Abasiophilia?

If one considers abasiophilia as a form of Body Integrity Identity Disorder (BIID), then treatments for that condition may be of some help in removing the obsessive compulsive (OCD) nature of abasiophilia in some people. As will be seen, there is some doubt that these treatments are effective.

It would be interesting to know if anyone with abasiophilia has approached their physician for treatment and whether SSRIs or similar have been offered. If so, what difference did it make to the obsessional feelings regarding leg-braces?

Medications should only be used with medical supervision.
Treatments which are being discussed for BIID are mentioned on the official BIID.org website and are quoted below, which is reproduced verbatim from that site.
  • Treatment of Primary Symptoms: There have been no systematic trials of medication to treat BIID. Anecdotally, a number of medications have been tried, including medications for depression, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, and psychosis.
  • SSRIs: Because of some of the similarities between BIID and obsessive-compulsive disorder (i.e., repetitive intrusive thoughts), treatment with medications used to alleviate symptoms of OCD, namely selective serotonin reuptake inhibitors such as prozac, paxil, zoloft, luvox, celexa, and lexapro, and combined SSRI/SNRIs (e.g., anafranil) would make sense. The effectiveness of such medications to treat BIID is unknown. In Dr. First's survey of 52 patients with a desire for amputation, 16 (out of 52) reported having taken one of these medications and none reported any decrease in their desire for amputation. It is important to note, however, that successful treatment of OCD often requires doses at the high end of the dose range for each of these medications (80 mg. for prozac, 200 mg. for zoloft, 50 mg. for paxil, 60 mg. for celexa, 40 mg of lexapro, 250 mg of anafranil) and most of these individuals were treated with much lower doses. Thus, we would recommend considering a trial of at least one of these medications at the top end of the dose range. Since individuals sometimes respond to one medication in this class and not to the others, we would also suggest trying several different medications. Finally, because patients with OCD sometimes respond only to anafranil, we would suggest trying this medication before concluding that this class of medication would not be helpful. (Anafranil is typically not the first choice because of its more troublesome side effect profile, including dry mouth, dizziness, sedation, etc.).
  • Stimulants: According to some BIID sufferers, there is a psychiatrist in the UK who claims success in treating the symptoms of BIID with stimulants. This physician reports of very high co-occurrence between BIID and ADHD and notes that treating the ADHD symptoms result in a secondary improvement in BIID symptoms. While ADHD did not appear to be common in Dr. First's sample of 52, the interview used by Dr. First did not systematically assess for ADHD symptoms.
  • 2nd Generation antipsychotics: (risperidal, olanzapine, seroquel, geodon, abilify). Although individuals withy BIID are not psychotic, these medications appear to be helpful in treating a number of conditions such as bipolar disorder, treatment-resistant depression, OCD, and symptoms such as agitation, anxiety, and disorganization. Anecdotally, at least one individual taking risperidal has reported a significant decrease in his desire for amputation. It probably makes sense to give at least one (if not several) medications from this class a try.
  • Treatment of Secondary Symptoms (e.g., depression). Depression is a common co-occurring symptom of BIID and several individuals in Dr. First's sample reported that while their antidepressant regimen did not diminish their desire for amputation, their depressive symptoms did respond. Thus, we recommend treatment of any additional symptoms with the appropriate medications (e.g. treating depression with antidepressants).