This is a page of Talmud in the traditional printing (from the late 19th century by a publishing house in Vilna, named the Widows and Brothers Romm).
In the center is the Mishnah and Talmud, and around the sides are a variety of commentaries from the tenth century to the 19th century.

For information on each block of the page, see Eliezer Segal's Image Map of the Talmud.